Sylantyev, Sergiy O Lee, Chia-Ming Shyu, Bai-Chuang
Published in
Neuroscience research
Paired-pulse facilitation (PPF) is a form of short-term plasticity that can be used qualitatively to characterize the synaptic effects of neuroactive compounds. As we have shown previously, CNQX has a marked effect on PPF which can be measured quantitatively. The aim of the present study was to examine quantitatively possible differences in the eff...
Uchida, Koichi Momiyama, Toshihiko Okano, Hideyuki Yuzaki, Michisuke Koizumi, Amane Mine, Yutaka Kawase, Takeshi
Published in
Neuroscience research
The fate of grafted neuroepithelial stem cells in the normal mature brain environment was assessed both morphologically and electrophysiologically to confirm their feasibility in the functional repair of damaged neural circuitry. The neuroepithelial stem cells were harvested from the mesencephalic neural plate of transgenic green fluorescence prote...
Koshiba, Mamiko Yohda, Masafumi Nakamura, Shun
Published in
Neuroscience research
In birds, there are two visual projections from retina to higher pallium, i.e., tectofugal and thalamofugal pathways. The latter one is lateralized in chick and suggested to be involved in visually evoked social behavior, like recognition of novelty, predator, and conspecific animals. We wanted to establish functionally relevant topological connect...
Constantinou, Caterina Bolaris, Stamatis Valcana, Theony Margarity, Marigoula
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Neuroscience research
Thyroid hormones (THs) are involved in the occurrence of anxiety and affective disorders; however, the effects following an anxiolytic benzodiazepine treatment, such as diazepam administration, on the mechanism of action of thyroid hormones has not yet been investigated. The effect of diazepam on the in vitro nuclear T3 binding, on the relative exp...
Seo, Kenji Fujiwara, Naoshi Takeuchi, Kiichi Maeda, Takeyasu Someya, Genji
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Neuroscience research
The postnatal development of nociceptive afferent activity expansion and its modulation features were examined in mice using an optical imaging technique. Developing mice (1-2 weeks old (N1-2 w), 3-4 weeks old (N3-4 w), 5-6 weeks old (N5-6 w) and 7-8 weeks old (N7-8 w)) and neonatally capsaicin-treated mice were used. The propagation of neuronal ex...
Sun, Hui Kawahara, Yukio Ito, Kyoko Kanazawa, Ichiro Kwak, Shin
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Neuroscience research
The differential expression of AMPA receptor subunit mRNA was analyzed in the adult rat brain and spinal cord using quantitative RT-PCR with laser capture microdissection. The expression of all four AMPA receptor subunits was demonstrable, with the mRNA expression level for GluR2 being the highest in all the brain areas and neuronal subsets examine...
Li, Hongbin Zhang, Jichuan Xiong, Wenyong Xu, Tianle Cao, Jun Xu, Lin
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Neuroscience research
The subiculum, which is the primary target of CA1 pyramidal neurons and sending efferent fibres to many brain regions, serves as a hippocampal interface in the neural information processes between hippocampal formation and neocortex. Long-term depression (LTD) is extensively studied in the hippocampus, but not at the CA1-subicular synaptic transmis...
Unuma, Kana Chen, Jie Saito, Shouichiro Kobayashi, Naoto Sato, Kohji Saito, Kyoko Wakisaka, Hiroyuki Mominoki, Katsumi Sano, Akira Matsuda, Seiji
...
Published in
Neuroscience research
Prosaposin is the precursor of saposins A, B, C and D, which are activators of sphingolipid hydrolases. In addition, unprocessed prosaposin functions as a neurotrophic factor in the central and peripheral nervous systems by acting to prevent neuronal apoptosis, to elongate neurites and to facilitate myelination. In this study, the expression patter...
Juh, Rahyeong Pae, Chi-Un Lee, Chang-Uk Yang, Dongwon Chung, Yongan Suh, Taesuk Choe, Boyoung
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Neuroscience research
The voxel-based analysis of 18F-FDG PET images showed detailed differences between IPD and MSA, which may be useful in differentiating the two disease entities, as evidenced by the correlation of glucose metabolism with disease severity and dopamine agonist medication. The mapping analysis of 18F-FDG PET images might be a useful adjunctive method o...
Oishi, Ayame Tobimatsu, Shozo Arakawa, Kenji Taniwaki, Takayuki Kira, Jun-ichi
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Neuroscience research
We recorded conjugate eye movements to elucidate whether ocular dominancy was present at reading distance in 21 normal volunteers with the right-handedness by using a video-oculographic (VOG) measurement. This included the velocity of smooth pursuits, and the latency and velocity of saccades. We defined the dominant eye for each subject by means of...
