Rode, Julia Yang, Lin König, Julia Hutchinson, Ashley Nicole Wall, Rebecca Venizelos, Nikolaos Brummer, Robert-Jan Rangel, Ignacio Vumma, Ravi
Published in
Neuropsychobiology
Butyrate is a short-chain fatty acid metabolite produced by microbiota in the colon. With its antioxidant properties, butyrate has also been shown to alter the neurological functions in affective disorder models, suggesting it as a key mediator in gut-brain interactions. Here, we evaluated the negative effect of oxidative stress on the transport of...
Hatzinger, Martin
Published in
Neuropsychobiology
Maramis, Margarita M Mahajudin, Marlina S Khotib, Junaidi
Published in
Neuropsychobiology
Depressive disorders are the 4th leading cause of health problems and the 2nd leading cause of burden among all diseases. Almost all depressive disorder patients have cognitive impairments to a certain extend. Studies about cognitive impairments in depression had been conducted, but whether cognitive dysfunctions are the cause or the effect is stil...
Guo, Yuan Zhang, Li Zhang, Jin Lv, Shu-Xuan Du, Cheng-Xue Wang, Tao Wang, Hui-Sheng Xie, Wen Liu, Jian
Published in
Neuropsychobiology
Background: The 5-hydroxytryptamine (5-HT) neurotransmitter system and lateral habenula (LHb) are involved in the regulation of depression, while the mechanisms remain to be clarified. Objectives: The effects and possible mecha-nism underlying activation or blockade of 5-HT4 receptors (5-HT4Rs) in the LHb in depression were investigated by behavior...
Janke, Eva Groh, Adrian Mühle, Christiane Dürsteler-MacFarland, Kenneth M. Wiesbeck, Gerhard A. Kornhuber, Johannes Jahn, Kirsten Groeschl, Michael Lichtinghagen, Ralf Frieling, Helge
...
Published in
Neuropsychobiology
Background/Aims: Opioid dependence is a severe disease which is associated with a high risk of relapse, even in cases of successful withdrawal therapy. Studies have shown alterations of the hypothalamic-pituitary-gonadal axis in opioid-dependent patients, such as decreased testosterone serum levels in affected males. Sex hormones and the steroid 5-...
Jahn, Kirsten Heese, Astrid Kebir, Oussama Groh, Adrian Bleich, Stefan Krebs, Marie Odile Frieling, Helge
Published in
Neuropsychobiology
Background: Patients suffering from schizophrenic psychosis show reduced synaptic connectivity compared to healthy individuals. Furthermore, the use of cannabis often precedes the onset of schizophrenic psychosis. Therefore, we investigated whether consumption of cannabis has an impact on the methylation pattern of schizophrenia candidate genes con...
Mahmoudi, Narges Kiasalari, Zahra Rahmani, Tayebeh Sanaierad, Ashkan Afshin-Majd, Siamak Naderi, Gholamali Baluchnejadmojarad, Tourandokht Roghani, Mehrdad
Published in
Neuropsychobiology
Objective: Prolonged diabetes mellitus causes impairments of cognition and attentional dysfunctions. Diosgenin belongs to a group of steroidal saponins with reported anti-diabetic and numerous protective properties. This research aimed to assess the effect of diosgenin on beneficially ameliorating learning and memory decline in a rat model of type ...
Mondragón-Maya, Alejandra Flores-Medina, Yvonne Silva-Pereyra, Juan Ramos-Mastache, Daniela Yáñez-Téllez, Guillermina Escamilla-Orozco, Raúl Saracco-Álvarez, Ricardo
Published in
Neuropsychobiology
Introduction: Schizoaffective disorder (SA) is classified into bipolar (bSA) and depressive (dSA) subtypes. Although clinical differences between both have been reported, there is no clear information regarding their specific cognitive profile. Objective: To compare neurocognition between SA subtypes and schizophrenia (SC). Methods: A total of 61 p...
Walther, Sebastian Morrens, Manuel
Published in
Neuropsychobiology
Kubera, Katharina M. Wolf, Nadine D. Rashidi, Mahmoud Hirjak, Dusan Northoff, Georg Schmitgen, Mike M. Romanov, Dmitry V. Sambataro, Fabio Frasch, Karel Wolf, Robert Christian
...
Published in
Neuropsychobiology
Background: Accumulating neuroimaging evidence suggests that abnormal intrinsic neural activity could underlie auditory verbal hallucinations (AVH) in patients with schizophrenia. However, little is known about the functional interplay between distinct intrinsic neural networks and their association with AVH. Methods: We investigated functional net...
