Labuz, Daniel F. Asch, Morris J. Buchmiller, Terry L.
Published in
Neonatology
Gastroschisis is a congenital abdominal wall defect that, when simple, has excellent overall outcomes. However, morbidity increases with prematurity. A staged approach to closure is often needed until the infant can tolerate definitive repair. We demonstrate the novel use of cadaveric skin allograft as a defect patch, exploiting a tolerant neonatal...
Bhatia, Ashwani Chua, Mei Chien dela Puerta, Rowena Rajadurai, Victor Samuel
Published in
Neonatology
Background: Hemolytic hyperbilirubinemia due to blood group incompatibility or glucose-6-phosphate dehydrogenase deficiency (G6PD) is a common cause of significant hyperbilirubinemia. Hemolysis in a hyperbilirubinemic infant increases the risk of bilirubin neurotoxicity. A new portable device (CoSense) can rapidly detect breath end-tidal carbon mon...
Nunes, Cristiane R. Procianoy, Renato S. Corso, Andréa L. Silveira, Rita C.
Published in
Neonatology
Introduction: Macrolides have anti-inflammatory and immunomodulatory properties that give this class of antibiotics a role that differs from its classical use as an antibiotic, which opens new therapeutic possibilities. Objective: The aim of this study was to evaluate the anti-inflammatory effect of azithromycin in preventing mechanical ventilation...
Salavati, Sahar Salavati, Masoud Coenen, Maraike A. ter Horst, Hendrik J. Bos, Arend F.
Published in
Neonatology
Parechovirus type 3 (HPeV-3) infection is an important cause of illness in neonates. We present the first case of an infant with a HPeV-3 meningoencephalitis which presumably commenced in utero. Severe developmental delay was seen. In the case of inexplicable neonatal meningoencephalitis, an intrauterine onset of HPeV-3 infection might be the cause...
Strunk, Tobias Hibbert, Julie Elizabeth Doherty, Dorota Nathan, Elizabeth Simmer, Karen Patole, Sanjay Keshav Trend, Stephanie Richmond, Peter Burgner, David Currie, Andrew
...
Published in
Neonatology
Background: Preterm infants are at a high risk of developing late-onset sepsis (LOS). Lactoferrin is one of the most abundant endogenous antimicrobial proteins expressed in breast milk, stools, and blood, and a candidate for preventive intervention. Large clinical trials have recently investigated whether enteral supplementation with bovine lactofe...
van Donge, Tamara Fuchs, Aline Leroux, Stéphanie Pfister, Marc Rodieux, Frédérique Atkinson, Andrew Giannoni, Eric van den Anker, John Bielicki, Julia
Published in
Neonatology
Introduction: Large variability in neonatal amoxicillin dosing recommendations may reflect uncertainty about appropriate efficacy and toxicity targets. Objective: The aim of this study was to model efficacious and safe exposure for current neonatal amoxicillin dosing regimens, given a range of assumptions for minimal inhibitory concentration (MIC),...
Poppe, Jarinda A. van Weteringen, Willem Völler, Swantje Willemsen, Sten P. Goos, Tom G. Reiss, Irwin K.M. Simons, Sinno H.P.
Published in
Neonatology
Introduction: Evaluation of pharmacotherapy during intensive care treatment is commonly based on subjective, intermittent interpretations of physiological parameters. Real-time visualization and analysis may improve drug effect evaluation. We aimed to evaluate the effects of the respiratory stimulant doxapram objectively in preterm infants using co...
Hermelijn, Sergei M. Zwartjes, Rutger R. Tiddens, Harm A.W.M. Cochius-den Otter, Suzan C.M. Reiss, Irwin K.M. Wijnen, René M.H. Schnater, J. Marco
Published in
Neonatology
Introduction: A congenital lung abnormality (CLA) is often found in conjunction with other abnormalities but screening guidelines for newborns with CLA have not yet been reported. We aimed to assess the incidence of associated anomalies in CLA patients born or followed up at our centre and the need for additional screening of newborns with a CLA. M...
van den Anker, John N.
Published in
Neonatology
Verhaeghe, Rebecca George, Kandie Westerman, Mark Olbina, Gordana McCann, Diane Parrow, Nermi Pincus, Elisa Havranek, Tomas Fleming, Robert E.
Published in
Neonatology
Introduction: The basis for the superior absorption of iron from breast milk compared with infant formulas is unclear. The hormone hepcidin downregulates dietary iron absorption. Hepcidin production increases with increased body iron status (reflected in serum ferritin levels). We hypothesized that serum hepcidin levels are suppressed relative to i...