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Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis

Published in Nature

Coronavirus disease 2019 (COVID-19) is a new pandemic disease caused by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The C5a anaphylatoxin and its receptor C5aR1 (CD88) play a key role in the initiation and maintenance of several inflammatory responses, by recruiting and activating neutrophils and monocytes in the lu...

Atmospheric molecular blobs shape up circumstellar envelopes of AGB stars.

Published in Nature

During their thermally pulsing phase, asymptotic giant branch (AGB) stars eject material that forms extended dusty envelopes1. Visible polarimetric imaging found clumpy dust clouds within two stellar radii of several oxygen-rich stars2-6. Inhomogeneous molecular gas has also been observed in multiple emission lines within several stellar radii of d...

Common genetic variants contribute more to rare diseases than previously thought.

Published in Nature

Brain-penetrating molecule might offer a route to treat glioblastoma tumours.

Published in Nature

Cancer cells impair monocyte-mediated T cell stimulation to evade immunity

Published in Nature

The tumor microenvironment (TME) is programmed by cancer cells and critically influences antitumor immune responses 1 , 2 . Within the TME, CD8+ T cells undergo full effector differentiation and acquire cytotoxic antitumor functions in specialized niches 3 – 7 . While interactions with type-1 conventional dendritic cells (cDC1s) have been implicate...

'I get paid for my outputs, not because I am Māori': why Indigenous researchers often face double duty.

Published in Nature

South Korea can boost the research potential of low-income countries.

Published in Nature

The next massive volcano eruption will cause climate chaos - and we are unprepared.

Published in Nature

Global warming is on the cusp of crucial 1.5 °C threshold, suggest ice-core data.

Published in Nature

Author Correction: Tumour-selective activity of RAS-GTP inhibition in pancreatic cancer.

Published in Nature