Peptide sequences for beta-crystallins of a teleost fish.
Published in Molecular vision
Fine mapping of the usher syndrome type IC to chromosome 11p14 and identification of flanking markers by haplotype analy...
Published in Molecular vision
The Usher Syndrome type 1C gene has been localized to a 1 cM interval between the markers D11S1397 and D11S1888 on chromosome 11p14.
A polymorphic trinucleotide repeat at DXS8170 in the critical region of X-linked retinitis pigmentosa locus RP3 at Xp21....
Published in Molecular vision
Isolation of differentially expressed human fovea genes: candidates for macular disease.
Published in Molecular vision
Genes that are more highly expressed in the fovea as opposed to the midperipheral retina are likely to represent essential genes for fovea function. Using our fovea cDNA library, we are able to isolate differential human fovea clones at an incidence of 41/10,000 clones screened. We demonstrate that there is a high level of differential gene express...
Expression of glial markers in a retinal precursor cell line.
Published in Molecular vision
There is a very strong glial component to the R28 retinal precursor cell line, as evidenced by the expression of proteins immunoreactive to GFAP, S-100 and vimentin. However, even the most strongly immunoreactive marker vimentin was compatible with co-expression of the photoreceptor marker IRBP as evidence of the "multi-phenotypic" nature of the pr...
Cloning and characterization of the cDNA encoding the alpha-subunit of cGMP-phosphodiesterase in canine retinal rod phot...
Published in Molecular vision
RPGR: part one of the X-linked retinitis pigmentosa story.
Published in Molecular vision
The gene for PEDF, a retinal growth factor is a prime candidate for retinitis pigmentosa and is tightly linked to the RP...
Published in Molecular vision
Genetic heterogeneity in autosomal dominant pattern dystrophy of the retina.
Published in Molecular vision
Mutations in the retinal degeneration slow (RDS)/peripherin gene have been shown to be associated with pattern dystrophy of the retina (PDR) and other retinal dystrophies. The aim of our study was to confirm or exclude the RDS locus and the rhodopsin (RHO) locus as the disease causing locus in a large Swiss family affected with pattern dystrophy of...
Long term light-induced retinal degeneration in the miniature pig.
Published in Molecular vision
In developing a model of slow light-induced retinal degeneration, ten miniature pigs were submitted to constant lighting for a period ranging from one to three months. Post-lighting survival time ranged from zero to two months. Control and illuminated animals were examined for pupillary reflex, underwent fundus examination and an electroretinogram....
