Published in Molecular Psychiatry
Correction to: Molecular Psychiatry (2015); advance online publication 22 September 2015; doi:10.1038/mp.2015.143 The first author in Reference 33 was listed incorrectly in the reference list and in the last paragraph of the Discussion section. The author’s last name should have been listed as Gottesman.
Published in Molecular psychiatry
Previous studies on schizophrenia have detected elevated cytokines in both brain and blood, suggesting neuroinflammation may contribute to the pathophysiology in some cases. We aimed to determine the extent to which elevated peripheral cytokine messenger RNA (mRNA) expression: (1) characterizes a subgroup of people with schizophrenia and (2) shows ...
Published in Molecular Psychiatry
Correction to: Molecular Psychiatry (2016); 21, 364–375; doi:10.1038/mp.2015.18 Following publication of the above article, the authors noticed that the row and column headings of Supplementary Table 1 were absent from the online version. The correct version of the table accompanies this erratum online.
Published in Molecular Psychiatry
The mechanisms responsible for fear memory formation and extinction are far from being understood. Uncovering the molecules and mechanisms regulating these processes is vital for identifying molecular targets for the development of novel therapeutic strategies for anxiety and fear disorders. Cognitive abilities require the activation of gene expres...
Published in Molecular psychiatry
Identification and characterization of molecular mechanisms that connect genetic risk factors to initiation and evolution of disease pathophysiology represent major goals and opportunities for improving therapeutic and diagnostic outcomes in Alzheimer's disease (AD). Integrative genomic analysis of the human AD brain transcriptome holds potential f...
Published in Molecular Psychiatry
Research in fear conditioning has provided a comprehensive picture of the neuronal circuit underlying the formation of fear memories. In contrast, our understanding of the retrieval of fear memories is much more limited. This disparity may stem from the fact that fear memories are not rigid, but reorganize over time. To bring some clarity and raise...
Published in Molecular Psychiatry
Antidepressants have been shown to improve longevity in C. elegans. It is plausible that orthologs of genes involved in mood regulation and stress response are involved in such an effect. We sought to understand the underlying biology. First, we analyzed the transcriptome from worms treated with the antidepressant mianserin, previously identified i...
Published in Molecular Psychiatry
The genetic basis of intellectual disability (ID) is extremely heterogeneous and relatively little is known about the role of autosomal recessive traits. In a field study performed in a highly inbred area of Northeastern Brazil, we identified and investigated a large consanguineous family with nine adult members affected by severe ID associated wit...
Published in Molecular psychiatry
Pathological expansion of a G4C2 repeat, located in the 5' regulatory region of C9orf72, is the most common genetic cause of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS). C9orf72 patients have highly variable onset ages suggesting the presence of modifying factors and/or anticipation. We studied 72 Belgian index ...
Published in Molecular Psychiatry
