Sengupta, Tanusree Majumder, Rinku Majumder, Samarpan
Published in
Molecular and Cellular Biochemistry
Aggressive inflammatory response leading to hypercoagulability has been found to be associated with disease severity in COVID-19 patients and portends bad treatment outcome. A state of acute disseminated intravascular coagulation (DIC), along with pulmonary embolism and/or deep vein thrombosis, has been observed in critically ill ICU patients. Auto...
Patel, Bhoomika Sharma, Supriya Nair, Nisha Majeed, Jaseela Goyal, Ramesh K. Dhobi, Mahaveer
Published in
Molecular and Cellular Biochemistry
The pandemic of Serious Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2) that produces corona virus disease (COVID-19) has challenged the entire mankind by rapidly spreading globally in 210 countries affecting over 25 million people and about 1 million deaths worldwide. It continues to spread, afflicting the health system globally. So far the...
Tarique, Mohammed Ahmad, Shaban Malik, Arshi Ahmad, Irfan Saeed, Mohd Almatroudi, Ahmad Qadah, Talal Murad, Manal Abdulaziz Mashraqi, Mutaib Alam, Qamre
...
Published in
Molecular and Cellular Biochemistry
Novel strain of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV2) causes mild to severe respiratory illness. The early symptoms may be fever, dry cough, sour throat, and difficulty in breathing which may lead to death in severe cases. Compared to previous outbreaks like SARS-CoV and Middle East Respiratory Syndrome (MERS), SARS-CoV2 disea...
Tyagi, Suresh C. Singh, Mahavir
Published in
Molecular and Cellular Biochemistry
Corona virus disease-19 (covid-19) is caused by a coronavirus that is also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), and is generally characterized by fever, respiratory inflammation, and multi-organ failure in susceptible hosts. One of the first things during inflammation is the response by acute phase proteins coupled...
Yi, Kezhen Rong, Yuan Wang, Cheng Huang, Lanxiang Wang, Fubing
Published in
Molecular and Cellular Biochemistry
Abstract SARS-CoV-2 is one of the beta-coronaviruses with the spike protein. It invades host cells by binding to angiotensin converting enzyme 2 (ACE2). This newly discovered virus can result in excessive inflammation and immune pathological damage, as shown by a decreased number of peripheral lymphocytes, increased levels of cytokines, and damages...
Acharya, Mohan Liyanage, Rohana Gupta, Anamika Arsi, Komala Donoghue, Ann M. Lay, Jackson O. Jr. Rath, Narayan C.
Published in
Molecular and Cellular Biochemistry
The sheared avian intestinal villus-crypts exhibit high tendency to self-repair and develop enteroids in culture. Presuming that this transition process involves differential biomolecular changes, we employed matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF–MS) to find whether there were differences in the spe...
Qiu, Jun Yang, Bei
Published in
Molecular and Cellular Biochemistry
Zhou, Huiling Liu, Lijun Ma, Xiaolong Wang, Jian Yang, Jinfu Zhou, Xinmin Yang, Yifeng Liu, Haidan
Published in
Molecular and Cellular Biochemistry
Vinblastine (VBL) has been considered as a first-line anti-tumor drug for many years. However, vinblastine-caused myocardial damage has been continually reported. The underlying molecular mechanism of the myocardial damage remains unknown. Here, we show that vinblastine induces myocardial damage and necroptosis is involved in the vinblastine-induce...
Wolak, Monika Bojanowska, Ewa Staszewska, Teresa Piera, Lucyna Szymański, Jacek Drobnik, Jacek
Published in
Molecular and cellular biochemistry
The inflammatory reaction influences the deposition of collagen within wound granulation tissue. The aim of the present study is to determine whether histamine acting directly on myofibroblasts derived from wound granulation tissue may influence collagen deposition. It also identifies the histamine receptor involved in this process. The experiments...
Turan, Belma Tuncay, Erkan
Published in
Molecular and Cellular Biochemistry
An important energy supplier of cardiomyocytes is mitochondria, similar to other mammalian cells. Studies have demonstrated that any defect in the normal processes controlled by mitochondria can lead to abnormal ROS production, thereby high oxidative stress as well as lack of ATP. Taken into consideration, the relationship between mitochondrial dys...