Molecular Bases of Endocrinopathies
Published in Molecular Endocrinology
Published in Molecular Endocrinology
Published in Molecular Endocrinology
Published in Molecular endocrinology (Baltimore, Md.)
Somatostatin (SRIF) is a 14-amino acid peptide hormone that is synthesized as part of a larger precursor, prepro-SRIF, consisting of a signal peptide and a proregion of 80-90 amino acids; mature SRIF is located at the carboxyl-terminus of the precursor. We have used a recombinant retroviral expression vector encoding anglerfish prepor-SRIF-I to inf...
Published in Molecular endocrinology (Baltimore, Md.)
These studies were designed to further elucidate the relative contributions of transcriptional and posttranscriptional mechanisms involved in beta-casein gene regulation in the mammary epithelial cell line designated COMMA-D and a clonal subline desginated HC-11. Primary transcripts were mapped under various hormonal and substratum conditions using...
Published in Molecular endocrinology (Baltimore, Md.)
Estrogens play an important role in normal physiology and in a variety of pathological states involving diverse tissues including breast and bone. The mechanism by which estrogens exert cell type- and disease-specific effects, however, remains to be explained. We have compared the gene expression profile of the MCF7 breast cancer cell line with tha...
Published in Molecular Endocrinology
Published in Molecular Endocrinology
Published in Molecular Endocrinology
Published in Molecular Endocrinology
Published in Molecular Endocrinology