Heidegger, Isabel Fotakis, Georgios Offermann, Anne Goveia, Jermaine Daum, Sophia Salcher, Stefan Noureen, Asma Timmer-Bosscha, Hetty Schäfer, Georg Walenkamp, Annemiek
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Published in
Molecular Cancer
Background Crosstalk between neoplastic and stromal cells fosters prostate cancer (PCa) progression and dissemination. Insight in cell-to-cell communication networks provides new therapeutic avenues to mold processes that contribute to PCa tumor microenvironment (TME) alterations. Here we performed a detailed characterization of PCa tumor endotheli...
Liang, Yiran Song, Xiaojin Li, Yaming Chen, Bing Zhao, Wenjing Wang, Lijuan Zhang, Hanwen Liu, Ying Han, Dianwen Zhang, Ning
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Published in
Molecular Cancer
Jin, Dan Guo, Jiwei Wu, Yan Yang, Lijuan Wang, Xiaohong Du, Jing Dai, Juanjuan Chen, Weiwei Gong, Kaikai Miao, Shuang
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Published in
Molecular Cancer
Bao, Hua Wang, Zheng Ma, Xiaoji Guo, Wei Zhang, Xiangyu Tang, Wanxiangfu Chen, Xin Wang, Xinyu Chen, Yikuan Mo, Shaobo
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Published in
Molecular Cancer
Early detection can benefit cancer patients with more effective treatments and better prognosis, but existing early screening tests are limited, especially for multi-cancer detection. This study investigated the most prevalent and lethal cancer types, including primary liver cancer (PLC), colorectal adenocarcinoma (CRC), and lung adenocarcinoma (LU...
Berlak, Mareike Tucker, Elizabeth Dorel, Mathurin Winkler, Annika McGearey, Aleixandria Rodriguez-Fos, Elias da Costa, Barbara Martins Barker, Karen Fyle, Elicia Calton, Elizabeth
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Published in
Molecular Cancer
Background Development of resistance to targeted therapies has tempered initial optimism that precision oncology would improve poor outcomes for cancer patients. Resistance mechanisms, however, can also confer new resistance-specific vulnerabilities, termed collateral sensitivities. Here we investigated anaplastic lymphoma kinase (ALK) inhibitor re...
Ren, Xiaofan Chen, Changhao Luo, Yuming Liu, Mingyang Li, Yuting Zheng, Shangyou Ye, Huilin Fu, Zhiqiang Li, Min Li, Zhihua
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Published in
Molecular Cancer
Nicot, Christophe
Published in
Molecular Cancer
Del Gaudio, Nunzio Di Costanzo, Antonella Liu, Ning Qing Conte, Lidio Dell’Aversana, Carmela Bove, Guglielmo Benedetti, Rosaria Montella, Liliana Ciardiello, Fortunato Carafa, Vincenzo
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Published in
Molecular Cancer
Background The dynamic epigenome and proteins specialized in the interpretation of epigenetic marks critically contribute to leukemic pathogenesis but also offer alternative therapeutic avenues. Targeting newly discovered chromatin readers involved in leukemogenesis may thus provide new anticancer strategies. Accumulating evidence suggests that the...
Xia, Xin Li, Xixi Li, Fanying Wu, Xujia Zhang, Maolei Zhou, Huangkai Huang, Nunu Yang, Xuesong Xiao, Feizhe Liu, Dawei
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Published in
Molecular Cancer
Hua, Jinghan Wang, Xiaolin Ma, Liying Li, Jingxin Cao, Guozhen Zhang, Shaobo Lin, Wenchu
Published in
Molecular Cancer
Background Multiple lines of evidence have demonstrated that circular RNAs (circRNAs) play oncogenic or tumor-suppressive roles in various human cancers. Nevertheless, the biological functions of circRNAs in small cell lung cancer (SCLC) are still elusive. Methods CircVAPA (annotated as hsa_circ_0006990) was identified by mining the circRNA profili...
