Why is the RUTH trial so important?
Published in Maturitas
The benefits of androgens combined with hormone replacement therapy regarding to patients with postmenopausal sexual sym...
Published in Maturitas
All data suggest that combined HRT-androgen therapy may be beneficial for postmenopausal women receiving HRT who continue to complain of sexual difficulties or for postmenopausal women with sexual complaints who are not undergoing estrogen therapy.
Tibolone (Livial) enhances warfarin-induced anticoagulation in postmenopausal women.
Published in Maturitas
Tibolone enhances warfarin-induced anticoagulation in postmenopausal women, as reflected by increases in INR and decreases in coagulation Factors II, VII, VIIa and X, compared to placebo. It is advisable to monitor for changes in coagulation status during (and after discontinuation of) simultaneous use of tibolone and warfarin.
Neurophysiologic changes during estrogen augmentation in perimenopausal depression.
Published in Maturitas
In women with perimenopausal depression, physiologic brain changes in the right frontal region during estrogen augmentation were associated with remission of depression.
Cognitive function in late versus early postmenopausal stage.
Published in Maturitas
Although there were no differences in attention, verbal fluency and memory, executive function was significantly poorer in the late postmenopausal stage women, suggesting that this aspect of cognition deteriorates more rapidly than other functions. This change was independent of change in age, suggesting that hormonal changes between the early and ...
The effect of tibolone versus 17beta-estradiol on climacteric symptoms in women with surgical menopause: a randomized, c...
Published in Maturitas
Our findings suggest that tibolone may improve mood, libido and somatic symptoms in surgically menopausal women to a greater extent than estrogen therapy alone.
Impact of seafood and fruit consumption on bone mineral density.
...Published in Maturitas
This study with its large population size has identified preventive measures, as well as some risk factors, involved in bone loss and osteoporosis. Our results highlight the importance of several dietary variables as significant determinants of BMD. It also emphasizes the role of dietary intake in general and shows that specific foods, such as frui...
Attitudes towards the menopause and hormone therapy over the turn of the century.
Published in Maturitas
Most Swedish women had a mainly biological view on menopause but nevertheless they thought that only women with climacteric symptoms should use HT. Women's attitudes towards HT have changed after recent reports on risks from long-term use of HT whereas the attitudes towards the menopausal transition were stable. Other factors than attitudes towards...
Raloxifene therapy interacts with serum osteoprotegerin in postmenopausal women.
Published in Maturitas
Osteoprotegerin (OPG) is a protein expressed by osteoblasts that, linking the receptor activator of nuclear factor kappaB (RANK) ligand (RANKL), produced by osteoblasts, blocks the process of osteoclastic differentiation and modulates osteoclastic apoptosis. Raloxifene (RAL) stimulates the production of OPG from osteoblasts, as demonstrated in vitr...
Knowledge of osteoporosis correlated with hormone therapy use and health status.
Published in Maturitas
Knowledge about osteoporosis among Czech women aged > or =40 years and attending outpatient centers is relatively poor. To improve it, special attention should be paid to elderly women, those who have not used HRT, poorly educated women and those treated with several drugs.
