Chiu, Hsien-Yi Wang, Wei-Hung Kuan, Chen-Hsiang Wu, Yueh-Feng Tseng, Chung-Jen Huang, Wen-Yen Wang, Shiou-Han Lin, Sung-Jan
Published in
Lasers in surgery and medicine
Depilatory laser targeting melanin has been widely applied for the treatment of hypertrichosis. Both selective photothermolysis and thermal diffusion have been proposed for its effect, but the exact mechanism of permanent hair reduction remains unclear. In this study, we explore the role of thermal diffusion in depilatory laser-induced permanent ha...
Erlendsson, Andrés M Rosenberg, Lukas K Lerche, Catharina M Togsverd-Bo, Katrine Wiegell, Stine R Karmisholt, Katrine Philipsen, Peter A Hansen, Anders C N Janfelt, Christian Holmes, Jon
...
Published in
Lasers in surgery and medicine
Patients with hypertrophic scars (HTS) risk reduced quality of life due to itching, pain, poor cosmesis, and restriction of movement. Despite good clinical efficacy, patients are often reluctant to undergo repeated needle injections due to pain or needle phobia. To evaluate the applicability of needle-free pneumatic jet injection (PJI) and assess c...
Fiala, Thomas Lavin, Philip
Published in
Lasers in surgery and medicine
The primary objective of this pilot study was to confirm the safety of a 1064-nm laser device with a novel robotic arm for noninvasive subcutaneous fat reduction in the flank area. Secondary objectives included: assessing the extent of subject discomfort during treatment, overall subject satisfaction with the results of the procedure, and a determi...
Bekmukhametova, Alina Uddin, Mir Muhammad Nasir Houang, Jessica Malladi, Chandra George, Laurel Wuhrer, Richard Barman, Shital K Wu, Ming J Mawad, Damia Lauto, Antonio
...
Published in
Lasers in surgery and medicine
Biocompatible nanoparticles have been increasingly used in a variety of medical applications, including photodynamic therapy. Although the impact of synthesis parameters and purification methods is reported in previous studies, it is still challenging to produce a reliable protocol for the fabrication, purification, and characterization of nanopart...
Zheng, Wenyue Zhu, Zhenlai Shi, Yanqiang Wen, Si Ye, Li Man, Maoqiang Yang, Bin Liu, Zhenfeng
Published in
Lasers in surgery and medicine
Ablative fractional CO2 laser (AFL) therapy is an effective intervention to induce dermal remodeling. AFL treatment of the skin triggers the recruitment of immune cells, with neutrophils dominating the early phase. However, the role of recruited neutrophils in AFL-induced microinjuries and their subsequent dermal remodeling capacity remains elusive...
Yao, Yi-Lin Wang, Yu-Feng Li, Chen-Xi Wu, Lan Tang, Guo-Yao
Published in
Lasers in surgery and medicine
This study aimed to review the results of oral leucoplakia (OL) using ablative fractional laser-assisted photodynamic therapy (AFL-PDT) and to further evaluate the risk factors for recurrence and malignant transformation. Forty-eight patients diagnosed with OL using histopathology were enrolled in this study. All patients received one session of AF...
Bik, Liora van Doorn, Martijn B A Boeijink, Neill Wennekers, Medelyn Meesters, Arne A Bloemen, Peter Haedersdal, Merete Wolkerstorfer, Albert
Published in
Lasers in surgery and medicine
Needle-free jet injectors have been used in dermatological practice for many years. However, predefined clinical endpoints that guide physicians to choose optimal device settings have not been clearly defined. Here, we evaluate immediate skin responses as clinical endpoints for needle-free jet injector treatments. We injected methylene blue in ex v...
Roter, Gustaw Szczerkowska-Dobosz, Aneta Nowicki, Roman J
Published in
Lasers in surgery and medicine
There are limited treatment options for nail psoriasis. It is important to find new therapies and improve existing ones. The aim of this study was to compare the effectiveness of pulsed dye laser (PDL) versus combined PDL and Nd:YAG lasers in patients with nail psoriasis. Fourteen patients (with a total of 126 nails affected by nail psoriasis) were...
Lim, Seonghee Truong, Van Gia Kang, Hyun Wook
Published in
Lasers in surgery and medicine
Tubular tissue, such as the bile duct and esophagus, often suffers from stenosis due to chronic inflammation or excessive contraction of smooth muscle. Laser treatment using a balloon catheter has been used to treat tubular tissue stenosis by mechanically expanding the tissue and irradiating laser light circumferentially on the tissue lumen. As the...
Akhter, Forhad Manrique-Bedoya, Santiago Moreau, Chris Smith, Andrea Lynn Feng, Yusheng Mayer, Kathryn M Hood, R Lyle
Published in
Lasers in surgery and medicine
Photothermal therapies have shown promise for treating pancreatic ductal adenocarcinoma when they can be applied selectively, but off-target heating can frustrate treatment outcomes. Improved strategies leveraging selective binding and localized heating are possible with precision medical approaches such as functionalized gold nanoparticles, but ca...
