Belikov, Andrey V Tavalinskaya, Anastasia D Smirnov, Sergey N
Published in
Lasers in surgery and medicine
A novel dual-stage method for active laser drug delivery (DSLADD) in the treatment of nail diseases is being presented. This method includes sequentially performed microporation of the nail with submillisecond pulses of Er:YLF laser radiation through a layer of an aqueous solution of drug deposited on the nail surface (Stage 1) and exposure this la...
Mehrabi, Joseph N Baugh, Erica G Fast, Alexander Lentsch, Griffin Balu, Mihaela Lee, Bonnie A Kelly, Kristen M
Published in
Lasers in surgery and medicine
Non-invasive optical imaging has the potential to provide a diagnosis without the need for biopsy. One such technology is reflectance confocal microscopy (RCM), which uses low power, near-infrared laser light to enable real-time in vivo visualization of superficial human skin from the epidermis down to the papillary dermis. Although RCM has great p...
O Connor, Kelly Cho, Sung Bin Chung, Hye Jin
Published in
Lasers in surgery and medicine
The aim of this study is to histologically characterize the wound healing process of in vivo human skin treated with 1064- and 532-nm microlens array (MLA)-type picosecond lasers. Three patients (Fitzpatrick skin types II-IV), who were undergoing future cosmetic abdominoplasties, were treated with 1064- and 532-nm MLA-type lasers under different fl...
Ross, Edward V Domankevitz, Yacov
Published in
Lasers in surgery and medicine
The 1064 nm wavelength is optimized for dark skin, but within the range of available fluences for commercially available 1064 nm devices, may not provide effective treatment for lighter hair. The 755 nm alexandrite wavelength can treat a full range of hair colors but is not ideal for darker skin. The hypothesis is that a new laser system capable of...
Wong, Christina S M Chan, Mandy W M Shek, Samantha Y N Yeung, Chi Keung Chan, Henry H L
Published in
Lasers in surgery and medicine
Facial melasma is a disfiguring pigmentation and occurs frequently with aging skin. Topical treatment alone was often suboptimal. A recent study showed that fractional picosecond laser has promising result in benign pigmentary lesions. This study aims to investigate the efficacy and safety of 1064 nm picosecond laser in treatment of facial melasma ...
Shimojo, Yu Nishimura, Takahiro Hazama, Hisanao Ito, Nobuhisa Awazu, Kunio
Published in
Lasers in surgery and medicine
In this study, the threshold fluences for disrupting the melanosomes for pigmented skin lesion treatment were determined using a 755-nm picosecond laser for clinical use. Based on the melanosome disruption thresholds, incident fluences corresponding to the target lesion depths were evaluated in silico for different laser spot sizes. Melanosome samp...
Nitayavardhana, Sunatra Manuskiatti, Woraphong Cembrano, Kathryn Anne G Wanitphadeedecha, Rungsima
Published in
Lasers in surgery and medicine
Phototherapy for acne with a combination of blue and red light-emitting diodes (LEDs) appears to have excellent potential in treating inflammatory acne. However, a standard twice-weekly protocol administered 3 days apart may not be practical for patients. This study aims to seek the efficacy of LED treatment in moderate to severe acne, comparing be...
Yu, Wenyou Zhu, Jiafang Yu, Wenxin Shang, Ying Lyu, Dongze Lin, Xiaoxi Xu, Hui Zhang, Zhen
Published in
Lasers in surgery and medicine
The long-term efficacy of a picosecond alexandrite laser (PSAL) with a diffractive lens array (DLA) for the treatment of photoaging is absent. To observe the long-term efficacy of PSAL for the treatment of photoaging. Each patient (n = 10) received 10 treatments at 2-week intervals. One side of the face was randomly selected for treatment. At 1, 3,...
Hendel, Kristoffer Ortner, Vinzent K Fuchs, Christine S K Eckhouse, Vardit Haedersdal, Merete
Published in
Lasers in surgery and medicine
We evaluated a new handheld stereoscopic imaging system capable of visualizing scars with digital three-dimensional (3D) models and providing automated morphometric estimates. The objective was to validate the repeatability and accuracy of intra- and inter-investigator scan results. Engineered metal plates with depressed and elevated model scars (n...
Yuan, Chao Wang, Xue Shang, Ying Chen, Xiangdong Xu, Hui Zhang, Zhen
Published in
Lasers in surgery and medicine
To compare changes in skin sensitivity before and after treatment with a 1064-nm Q-switched Nd:YAG laser in healthy individuals, and to provide a reference for clinicians to use this laser reasonably. Nineteen healthy female volunteers underwent 10 random unilateral 1064-nm Q-switched Nd:YAG laser treatments. The skin transepidermal water loss rate...
