Published in Lab on a chip
Interspecies interactions inside microbial communities bear a tremendous diversity of complex chemical processes that are by far not understood. Even for simplified, often synthetic systems, the interactions between two microbes are barely revealed in detail. Here, we present a microfluidic co-cultivation platform for the analysis of growth and int...
Published in Lab on a chip
A wide range of microfluidic devices for single stream focusing of cells and particles has emerged in recent years, based on both passive and active methods. Inertial microfluidics offers an attractive alternative to these methods, providing efficient and sheathless passive focusing of cells and beads. Nevertheless, in rectangular microchannels, th...
Published in Lab on a chip
Wearable technologies have potential to transform healthcare by providing continuous measurements of physiological parameters. Sensors that passively monitor physiological pressure without using electronic components are ideal for wearable contact lenses because they are easy to interface with the cornea and the external environment. Here, we repor...
Published in Lab on a chip
Sensitive and accurate quantification of HIV RNA could be achieved using digital NASBA in an SD-chip
Published in Lab on a chip
Droplet microfluidics enables cellular encapsulation for biomedical applications such as single-cell analysis, which is an important tool used by biologists to study cells on a single-cell level, and understand cellular heterogeneity in cell populations. However, most cell encapsulation strategies in microfluidics rely on random encapsulation proce...
Published in Lab on a chip
Rare cell populations provide a patient-centric tool to monitor disease treatment, response, and resistance. However, understanding rare cells is a complex problem, which requires cell isolation/purification and downstream molecular interrogation - processes challenged by non-target populations, which vary patient-to-patient and change with disease...
Published in Lab on a chip
Cell-free DNA (cfDNA) is a liquid biopsy marker that can carry signatures ( i.e ., mutations) associated with certain pathological conditions. Therefore, the extraction of cfDNA from a variety of clinical samples can be an effective and minimally invasive source of markers for disease detection and subsequent management. In the oncological diseases...
Published in Lab on a chip
Microfluidic gradient generators are used to study the movement of living cells, lipid vesicles, and colloidal particles in response to spatial variations in their local chemical environment. Such gradient driven motions are often slow (less than 1 μm s-1) and therefore influenced or disrupted by fluid flows accompanying the formation and maintenan...
Published in Lab on a chip
Biological studies on in vitro cell cultures are of fundamental importance to investigate cell response to external stimuli, such as new drugs for the treatment of specific pathologies, or to study communication between electrogenic cells. Although three-dimensional (3D) nanostructures brought tremendous improvements on biosensors used for various ...
Published in Lab on a chip
The global healthcare landscape is experiencing increasing demand for CLIA-waived testing facilities that offer diagnostic capabilities at lower costs and greater convenience than traditional laboratory testing. While several new diagnostic tools have emerged to fulfill testing requirements in these environments, centrifuges have been stymied from ...
