Gurkan, Umut A Wood, David K Carranza, Dorn Herbertson, Luke H Diamond, Scott L Du, E Guha, Suvajyoti Di Paola, Jorge Hines, Patrick C Papautsky, Ian
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Published in
Lab on a chip
Microfluidic lab-on-a-chip technologies enable the analysis and manipulation of small fluid volumes and particles at small scales and the control of fluid flow and transport processes at the microscale, leading to the development of new methods to address a broad range of scientific and medical challenges. Microfluidic and lab-on-a-chip technologie...
Lee, Chaeeun Kumar, Sumit Park, Juhee Choi, Yongjun Clarissa, Elizabeth Maria Cho, Yoon-Kyoung
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Lab on a chip
The current challenge in using extracellular vesicles (EVs) as drug delivery vehicles is to precisely control their membrane permeability, specifically in the ability to switch between permeable and impermeable states without compromising their integrity and functionality. Here, we introduce a rapid, efficient, and gentle loading method for EVs bas...
Chen, Xiaoming Shen, Mo Liu, Shun Wu, Chungang Sun, Liangliang Song, Zhipeng Shi, Jishun Yuan, Yulong Zhao, Yong
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Lab on a chip
Marine microalgae play an increasingly significant role in addressing the issues of environmental monitoring and disease treatment, making the analysis of marine microalgae at the single-cell level an essential technique. For this, we put forward accurate and fast microfluidic impedance cytometry to analyze microalgal cells by assembling two cylind...
Schlünder, Katharina Cipriano, Madalena Zbinden, Aline Fuchs, Stefanie Mayr, Torsten Schenke-Layland, Katja Loskill, Peter
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Lab on a chip
Pancreatic in vitro research is of major importance to advance mechanistic understanding and development of treatment options for diseases such as diabetes mellitus. We present a thermoplastic-based microphysiological system aiming to model the complex microphysiological structure and function of the endocrine pancreas with concurrent real-time rea...
Staskiewicz, Klaudia Dabrowska-Zawada, Maria Kozon, Lukasz Olszewska, Zofia Drewniak, Lukasz Kaminski, Tomasz S
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Lab on a chip
Traditional methods for the enrichment of microorganisms rely on growth in a selective liquid medium or on an agar plate, followed by tedious characterization. Droplet microfluidic techniques have been recently used to cultivate microorganisms and preserve enriched bacterial taxonomic diversity. However, new methods are needed to select droplets co...
Verbist, Wannes Breukers, Jolien Sharma, Sapna Rutten, Iene Gerstmans, Hans Coelmont, Lotte Dal Dosso, Francesco Dallmeier, Kai Lammertyn, Jeroen
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Lab on a chip
Fluorescence-activated droplet sorting (FADS) has emerged as a versatile high-throughput sorting tool that is, unlike most fluorescence-activated cell sorting (FACS) platforms, capable of sorting droplet-compartmentalized cells, cell secretions, entire enzymatic reactions and more. Recently, multiplex FADS platforms have been developed for the sort...
Zhao, Meiying Tao, Ye Guo, Wenshang Ge, Zhenyou Hu, Hanqing Yan, Ying Zou, Chaoxia Wang, Guiyu Ren, Yukun
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Lab on a chip
Soft actuators capable of remote-controlled guidance and manipulation within complex constrained spaces hold great promise in various fields, especially in medical fields such as minimally invasive surgery. However, most current magnetic drive soft actuators only have the functions of position control and guidance, and it is still challenging to ac...
Olaizola-Rodrigo, Claudia Palma-Florez, Sujey Ranđelović, Teodora Bayona, Clara Ashrafi, Mehran Samitier, Josep Lagunas, Anna Mir, Mònica Doblaré, Manuel Ochoa, Ignacio
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Published in
Lab on a chip
Organ-on-chip (OOC) technology has recently emerged as a powerful tool to mimic physiological or pathophysiological conditions through cell culture in microfluidic devices. One of its main goals is bypassing animal testing and encouraging more personalized medicine. The recent incorporation of hydrogels as 3D scaffolds into microfluidic devices has...
Apoorva, Sasikala Nguyen, Nam-Trung Sreejith, Kamalalayam Rajan
Published in
Lab on a chip
Wearable devices are gaining popularity in the fields of health monitoring, diagnosis, and drug delivery. Recent advances in wearable technology have enabled real-time analysis of biofluids such as sweat, interstitial fluid, tears, saliva, wound fluid, and urine. The integration of microfluidics and emerging smart technologies, such as artificial i...
Lehnert, Thomas Gijs, Martin A M
Published in
Lab on a chip
Microorganisms, encompassing both uni- and multicellular entities, exhibit remarkable diversity as omnipresent life forms in nature. They play a pivotal role by supplying essential components for sustaining biological processes across diverse ecosystems, including higher host organisms. The complex interactions within the human gut microbiota are c...