David, L Betend, B Berlier, P Evrard, A Guinard, A François, R
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Vaginal bleeding in young girls without other signs of precocious sexual development is rare. We report a series of 33 cases observed during a 21 year period in the departments of pediatrics of the University of Lyon. Among the various etiologies, vaginal foreign bodies (10 cases, 30%) and vaginitis (10 cases, 30%) were the most frequent. There wer...
Fays, J Claudon, M Bernard, C Bretagne, M C Grosdidier, G
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
I.V. arterio-nephro- urotomogram turns out to be very useful in the work-up of renal traumas mainly by studying the cortical phase and the arterial phase. This technique allows to limit the indications for selective renal arteriogram.
Boyer, M Barat, M Mazaux, J M Debelleix, X Arné, L
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Three new cases of myelopathy without compression associated with paraproteinemia are reported. The neurologic picture was that of spinal muscular atrophy in one case and chronic spinal combined sclerosis in two. The nature of the paraproteinemia is discussed: all three patients seem to have had benign monoclonal dysglobulinemia. One patient died f...
Reiffers, J David, B Bernard, P Vezon, G Marit, G Moulinier, J Broustet, A
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Two patients with chronic granulocytic leukemia (C.G.L.) undergoing transformation were treated by high dose chemotherapy and total body irradiation followed by autografting of hematopoietic stem cells collected and cryo-preserved at the time of diagnosis. Recovery of hematopoiesis was characterized by disappearance of the Philadelphia chromosome i...
Dorra, M Piette, A M Dechy, H Betourne, C
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
The diagnosis of temporal arteritis is made after a mean delay of four months. This delay is explained by the absence, in 50% of cases, of any clinical sign in the temporal area, the possible presence of alterations in liver function tests, and the frequency of anemia and loss of weight. These signs often suggest a mistaken diagnosis of hepatobilia...
Vial, P Boachon, G Meilland, M Mianne, D Fontvielle, P George, M Marion, P
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
The authors report the case of a 60-year-old man presenting with an esophagobronchial fistula. The congenital origin of the lesion was demonstrated by the history of the clinical symptomatology and by radiological, endoscopic and anatomical arguments. While it is a rare complaint in adults, it is worth considering in the diagnosis of a chronic coug...
Doyard, P Mattei, J F
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
A new familial observation of Cohen syndrome in two sisters is reported. Both children exhibited the typical features of Cohen syndrome, i.e. obesity, hypotonia, mental deficiency and a dysmorphic syndrome mainly involving the facies and extremities. More accurate delineation of the nosologic limits of this syndrome is ensured by a critical review ...
Wattre, P
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Much clinical and experimental data is in support of a significant role played by viruses in the etiology of diabetes mellitus. This hypothesis is borne out by the association of diabetes mellitus with Coxsackie B, mumps, rubella and herpes simplex virus infections, the presence of high persistent titers of neutralizing antibodies in diabetic patie...
Falardeau, P Martineau, A Gagnon, D
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Prostaglandins and thromboxanes are 20-carbon-atom-chain fatty acids which contain a cyclopentane or oxane nucleus respectively. They belong to a family of icosanoids whose main intracellular precursor is arachidonic acid. These icosanoids are synthetized in all tissues (except red cells). Enzymatic hydrolysis of the arachidonic acid of lipids is t...
Adrien, A Guillet, G
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La semaine des hôpitaux : organe fondé par l'Association d'enseignement médical des hôpitaux de Paris
Porphyria cutanea tarda (PCT) is the most common porphyria. In contrast to the other porphyrias, which are undisputably hereditary, PCT was long considered to be acquired. However, the recent demonstration of a defect in uroporphyrinogen decarboxylase suggests that PCT is supported by a genetic factor. Though the hereditary or acquired nature of th...
