Published in Kompass Pneumologie
Trotz der jüngsten bedeutenden Innovationen in der Behandlung der chronisch-obstruktiven Lungenerkrankung (chronic obstructive pulmonary disease, COPD) wurden in der patientenzentrierten Medizin keine wesentlichen Fortschritte erzielt. Die Empfehlungen der aktuellen Leitlinien basieren auf den Durchschnittsergebnissen klinischer Studien, was zur Fo...
Published in Kompass Pneumologie
Published in Kompass Pneumologie
Published in Kompass Pneumologie
Background: Patients suffering from fibrotic interstitial lung diseases (fILD) have a poor prognosis and a high symptom burden. Palliative treatment includes relief of symptoms such as breathlessness. There is no evidence-based treatment for chronic breathlessness but opioids are often used despite concerns due to the hypothetical risk of respirato...
Published in Kompass Pneumologie
Hintergrund: Über den Nutzen einer intensivierten Immunsuppression bei Patienten mit schwerer interstitieller Pneumonie, die mit Zeichen einer Autoimmunerkrankung oder neu auftretenden Bindegewebserkrankung assoziiert ist, liegen nur begrenzte klinische Daten vor. Fallbericht: In der vorliegenden Arbeit berichten wir über eine Serie von 3 aufeinand...
Published in Kompass Pneumologie
Objectives: To evaluate initial combination therapy with ambrisentan plus tadalafil (COMB) compared with monotherapy of either agent (MONO), and the utility of baseline characteristics and risk stratification in predicting outcomes, in patients with connective tissue disease-associated pulmonary arterial hypertension (CTD-PAH) and the systemic scle...
Published in Kompass Pneumologie
Nailfold videocapillaroscopy (NVC) is an easy tool used for the assessment of patients with Raynaud’s phenomenon (RP) as possibly associated with systemic sclerosis (SSc). Recent insights have also highlighted its role in the diagnostic assessment of idiopathic inflammatory myopathies (IIMs). The aim of this study is to describe the diagnostic role...
Published in Kompass Pneumologie
Objectives: To identify overall disease course, progression patterns and risk factors predictive for progressive interstitial lung disease (ILD) in patients with systemic sclerosis-associated ILD (SSc-ILD), using data from the European Scleroderma Trials And Research (EUSTAR) database over long-term follow-up. Methods: Eligible patients with SSc-IL...
Published in Kompass Pneumologie
Medication non-adherence is associated with sub-optimal asthma control. Identification of medical and psychological characteristics associated with non-adherence is important to enable a targeted and personalized approach when working with patients and for the development of interventions to improve patient outcomes by improving medication adherenc...
Published in Kompass Pneumologie
Background: Exposure to carbon monoxide (CO) remains a leading occupational hazard in firefighters, but cigarette and waterpipe smoking likely contributes to the other sources of CO in such workers. The aim of this study was to estimate the contribution of self-reported active cigarette smoking, waterpipe use, and potential job-related sources of C...
