Sistrunk, J Woody Shifrin, Alexander Frager, Marc Bardales, Ricardo H Thomas, Johnson Fishman, Norman Goldberg, Philip Guttler, Richard Grant, Edward
Published in
Journal of the American Society of Cytopathology
We evaluated the clinical performance of an expanded mutation panel in combination with microRNA classification (MPTX) for the management of indeterminate thyroid nodules. MPTX included testing of fine-needle aspirates from multiple centers with a combination of ThyGeNEXT mutation panel for strong and weak driver oncogenic changes and ThyraMIR micr...
Jug, Rachel Giovacchini, Coral X Liu, Beiyu Green, Cynthia L Clarke, Jeffrey M Mahmood, Kamran Pavlisko, Elizabeth N
Published in
Journal of the American Society of Cytopathology
Immune checkpoint pathway markers induce immune tolerance to non-small cell lung cancer (NSCLC). Therapeutic antibodies targeting the programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway have demonstrated efficacy in tumors expressing relatively high PD-L1 levels. Minimally invasive endobronchial ultrasound-guided fine need...
Mustafa, Sara VandenBussche, Christopher J Ali, Syed Z Siddiqui, Momin T Wakely, Paul E Jr
Published in
Journal of the American Society of Cytopathology
Low-grade fibromyxoid sarcoma (LGFMS) is a rare fibroblastic tumor characterized by a prolonged clinical course and malignant biological behavior. Given its deceptively bland cytomorphology, a diagnosis can be quite challenging notably on fine-needle aspiration (FNA). In an attempt to shed light on some of the distinctive cytomorphologic characteri...
Coppock, Joseph D Dusenbery, Anna C Elghawy, Omar Fellenstein, Lynn A Frierson, Henry F Jr Shildkrot, Yevgeniy
Published in
Journal of the American Society of Cytopathology
Hereditary amyloidosis is a challenging but critical diagnosis, with serious implications with regard to treatment and disease surveillance for both patients and their families. Systemic symptomology is often vague. As vitreous amyloid deposition is strongly linked to the systemic, hereditary disease, its cytodiagnosis in the vitreous may be the in...
Miller, Daniel L Thompson, Lester D R Bishop, Justin A Rooper, Lisa M Ali, Syed Z
Published in
Journal of the American Society of Cytopathology
Voskuil, Ryan T Mayerson, Joel L Scharschmidt, Thomas J
Published in
Journal of the American Society of Cytopathology
Fine-needle aspiration (FNA) has been a widely accepted practice in the diagnosis of head and neck, thyroid, lung, pancreas, and many other visceral sites. This has not been the case with the diagnosis of primary bone and soft tissue lesions. FNA has been an important part of our orthopaedic oncology practice for 18 years. Our ability to efficientl...
Thrall, Michael J Vrbin, Colleen Barkan, Güliz A Monaco, Sara E Pambuccian, Stefan E Pantanowitz, Liron Pitman, Martha B Kurtycz, Daniel F I
Published in
Journal of the American Society of Cytopathology
The introduction of a new generation of core needle biopsies (CNBs) for endoscopic procedures has prompted reconsideration of the role of cytopathologists in the handling of small biopsies. The American Society of Cytopathology (ASC) has therefore conducted a survey with the intention of elucidating current practices regarding the handling of small...
Sung, Simon Heymann, Jonas J Crapanzano, John P Moreira, Andre L Shu, Catherine Bulman, William A Saqi, Anjali
Published in
Journal of the American Society of Cytopathology
In the 21st century, there has been a dramatic shift in the management of advanced-stage lung carcinoma, and this has coincided with an increasing use of minimally invasive tissue acquisition methods. Both have had significant downstream effects on cytology and small biopsy specimens. Current treatments require morphologic, immunohistochemical, and...
Manucha, Varsha Patel, Tejal Grunes, Dianne Akhtar, Israh
Published in
Journal of the American Society of Cytopathology
Human papilloma virus (HPV)-associated oropharyngeal squamous cell carcinoma (HPV-OPSCC) has been recognized to have an excellent response to treatment and has a distinct pathologic staging. For this reason, HPV testing is recommended in cytology specimens of metastatic OPSCC, although the guidelines for testing are not clearly defined. The aim of ...
Kurtycz, Daniel F I Rossi, Ester Diana Baloch, Zubair Pavelec, Derek Madrigal, Emilio Vielh, Philippe Faquin, William
Published in
Journal of the American Society of Cytopathology
Prior to the 2018 publication of the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC), a Web-based interobserver study was performed to evaluate MSRSGC reporting categories, identify cytomorphologic features that represent poor sources of agreement, and establish a baseline for future studies. Study participants evaluated 75 images ...
