Shii, Daisuke Oda, Tomoko Shinomiya, Katsuhiko Katsuta, Osamu Nakamura, Masatsugu
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Those results suggest that administration of cyclosporine A eye drops inhibit the early-phase reaction in type-I allergic conjunctivitis, which may be mediated by the suppression of mast cell degranulation. This action of cyclosporine A eye drops may be involved in the therapeutic effect of cyclosporine A on allergic conjunctivitis.
Proksch, Joel W Granvil, Camille P Siou-Mermet, Raphaële Comstock, Timothy L Paterno, Michael R Ward, Keith W
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Taken together, the results of the current investigation provide a PK/PD-based rationale that supports the use of besifloxacin for the safe and effective treatment of ocular infections.
Goze, Ismihan Alim, Ahmet Dag, Seker Tepe, Bektas Polat, Zubeyde Akin
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Methanolic extract of S. staminea could be considered a new natural agent against Acanthamoeba. However, further evaluation by in vivo testing is needed to confirm the efficiency of its biological effect.
Chen, Weiwei Yu, Man Wang, Yun Peng, Youwei Li, Xiaokun Lam, Dominic Man-Kit Chen, Xiaoming Liu, Xuyang
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Intravitreal delivery of nm-haFGF appears to have neuroprotective effect on retinal degeneration induced by NaIO(3).
Ebihara, Nobuyuki Ohashi, Yuichi Uchio, Eiichi Okamoto, Shigeki Kumagai, Naoki Shoji, Jun Takamura, Etsuko Nakagawa, Yayoi Nanba, Kenichi Fukushima, Atsuki
...
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Topical cyclosporine 0.1% is an effective and safe treatment for VKC and AKC.
He, Lingmin Ta, Christopher N Hu, Nan Sinnar, Shamim Miño de Kaspar, Herminia
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
In patients undergoing intraocular anterior segment surgery, 1-day and 3-day applications of topical 0.5% moxifloxacin appear to have similar efficacy in reducing perioperative conjunctival bacteria.
Dismuke, William M Ellis, Dorette Z
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
BK(Ca) channel activation increases outflow facility and decreases cell volume suggesting that K(+) efflux regulates TM cell function.
Hesje, Christine K Borsos, Shantelle D Blondeau, Joseph M
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
BAK substantially lowered the MIC and MPC of gatifloxacin and moxifloxacin against Gram-positive staphylococci compared to gatifloxacin alone, moxifloxacin alone, and/or levofloxacin. These findings suggest that the presence of BAK in the ophthalmic formulation of gatifloxacin (Zymar) may serve to enhance the potency of gatifloxacin and decrease it...
Huang, Yan Xu, Guoxing Peng, Yiru Chen, Shaoqiang Wu, Yunxia
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
The ratio of ZnPcS(4)-BSA content in RPE cells reached its peak after 4 h incubation. Intracellular ROS formation and the loss of Deltapsi(m) may play an important role in mediating the apoptotic processes of RPE cells induced by ZnPcS(4)-BSA based PDT. This study revealed that there is an important precondition to decrease the damage on RPE, that ...
Shin, Jae Pil Park, Yong Chul Oh, Ji Hae Lee, Ji Woong Kim, Yu Mi Lim, Jeong Ok Kim, Si Yeol
Published in
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
The biodegradable intrascleral TA implant was found to be effective at suppressing the inflammation induced by experimental uveitis in rabbits for at least 4 weeks.
