Dick, Katherine Briggs, Andrew Ohsfeldt, Robert Sydendal Grand, Tobias Buchs, Sarah
Published in
Journal of medical economics
Aims: Allergic rhinitis is caused by sensitivity to environmental allergens that can significantly impact quality-of-life. The objective of this analysis was to estimate health state utilities and quality-adjusted life days (QALDs) for a tree allergy immunotherapy trial, TT-04 (EudraCT No.2015-004821-15). Health-state utilities are a measure of pat...
Ueno, Fumiaki Doi, Michio Kawai, Yumi Ukawa, Naoto Cammarota, Jordan Betts, Keith A
Published in
Journal of medical economics
Aims: Adalimumab, infliximab, and ustekinumab have been approved for patients with moderate-to-severe Crohn's disease in Japan. This study compared the relative efficacy and cost-effectiveness of adalimumab, infliximab, and ustekinumab in patients with Crohn's disease based on data from randomized controlled trials.Methods: Data were extracted from...
Floros, Lefteris Pagliuca, Antonio Taie, Amer Al Weidlich, Diana Rita Capparella, Maria Georgallis, Mihalina Sung, Anita Hor-Yun
Published in
Journal of medical economics
Aims: To estimate the cost-effectiveness of isavuconazole compared with the standard of care, voriconazole, for the treatment of patients with invasive fungal infection disease when differential diagnosis of the causative pathogen has not yet been achieved at treatment initiation.Materials and methods: The economic model was developed from the pers...
Cai, Qian Teeple, Amanda Wu, Bingcao Muser, Erik
Published in
Journal of medical economics
Objective: To describe the prevalence and costs of anxiety and depression among moderate-to-severe psoriasis (PsO) patients in a commercially-insured US population.Methods: The IBM MarketScan Commercial database was used to select adults with moderate-to-severe PsO (≥1 PsO diagnosis and ≥1 systemic or biologic medication) within each calendar year ...
Berdugo, Mauricio A Kirson, Noam Y Zimmer, Louise Beyhaghi, Hadi Toback, Seth Scarpati, Lauren M Stone, Michael N Dember, Ross Tseng-Tham, Joshua Wen, Jody
...
Published in
Journal of medical economics
Purpose: To evaluate the budget impact of adding a diagnostic test of tissue inhibitor of metalloproteinase 2 and insulin-like growth factor binding protein 7 ([TIMP-2]·[IGFBP7]), which identifies patients at risk of moderate-to-severe acute kidney injury (AKI), to the current standard of care (SOC) in a hospital setting.Materials and methods: A bu...
Teeple, Amanda Muser, Erik
Published in
Journal of medical economics
Aims: To estimate annual cost per response (CPR) in the US and number needed to treat (NNT) among patients receiving guselkumab or adalimumab treatment for moderate-to-severe plaque psoriasis (PsO).Materials and methods: Results from VOYAGE 1, a double-blind, placebo-controlled, head-to-head, 48-week study of guselkumab compared with adalimumab in ...
Shih, Tiffany M Sail, Kavita R Jalundhwala, Yash J Sullivan, Jeffrey van Eijndhoven, Emma Zadikoff, Cindy Marshall, Thomas S Lakdawalla, Darius N
Published in
Journal of medical economics
Aims: To estimate the relationship between functional status (FS) impairment and nursing home admission (NHA) risk in Parkinson's disease (PD) patients, and quantify the effect of advanced PD (APD) treatment on NHA risk relative to standard of care (SoC).Materials and methods: PD patients were identified in the Medicare Current Beneficiary Survey (...
Amin, Alpesh Deitelzweig, Steven Bucior, Iwona Lin, Jay Lingohr-Smith, Melissa Menges, Brandy Neuman, W Richey
Published in
Journal of medical economics
Objectives: This study evaluated the frequency of hospital readmissions for venous thromboembolism (VTE) and the associated costs and length of stay (LOS) among acute medically ill patients in the US using a real-world claims database analysis. Methods: Patients (≥40 years of age) at risk of VTE due to hospitalization for acute medical illnesses, b...
Zhao, Xiaohui Shah, Drishti Gandhi, Kavita Wei, Wenhui Dwibedi, Nilanjana Webster, Lynn Sambamoorthi, Usha
Published in
Journal of medical economics
Aim: To examine associations of opioid use and pain interference with activities (PIA), healthcare resource utilization (HRU) and costs, and wage loss in noninstitutionalized adults with osteoarthritis in the United States (US). Methods: Adults with osteoarthritis identified from the Medical Expenditure Panel Survey for 2011/2013/2015 were stratifi...
Barqawi, Yazan K Borrego, Matthew E Roberts, Melissa H Abraham, Ivo
Published in
Journal of medical economics
Aims: Among patients diagnosed with prostate cancer, 10-20% will develop castration-resistant prostate cancer (CRPC) within 5 years; for 70%, CRPC will metastasize, mostly to the lungs and/or liver. We performed a cost-effectiveness model comparing abiraterone plus prednisone (ABI + PRD), cabazitaxel plus prednisone (CAB + PRD) and enzalutamide (EN...
