CAR T-cells: costs, comparisons, and commentary.
Published in Journal of medical economics
Modeling operational quality metrics and costs of long-acting antibiotics for acute bacterial skin and skin structure in...
Published in Journal of medical economics
Aims: To model implementation of a new treatment pathway leveraging long-acting antibiotics (LAs) for treatment of acute bacterial skin and skin structure infections (ABSSSIs) in a hospital emergency department (ED) with an observation unit, and to quantify health resource utilization and economic outcomes versus standard care (intravenous vancomyc...
Overall survival, costs, and healthcare resource use by line of therapy in Medicare patients with newly diagnosed metast...
Published in Journal of medical economics
Aims: Medicare patients with metastatic or surgically unresectable urothelial carcinoma (mUC) often receive platinum-based chemotherapy as first line of therapy (LOT), but invariably progress, requiring additional LOTs and healthcare resource use (HCRU). To better understand the evolving mUC treatment landscape, the economic burden of chemotherapy-...
Bias-corrected estimates of reduction of post-surgery length of stay and corresponding cost savings through the widespre...
Published in Journal of medical economics
Background: Fast-tracking is an approach adopted by Mayo Clinic in Florida's (MCF) liver transplant (LT) program, which consists of early tracheal extubation and transfer of patients to surgical ward, eliminating a stay in the intensive care unit in select patients. Since adopting this approach in 2002, MCF has successfully fast-tracked 54.3% of pa...
Cost-effectiveness of second-line atezolizumab in Canada for advanced non-small cell lung cancer (NSCLC).
...Published in Journal of medical economics
Aim: To assess the cost-effectiveness in Canada of atezolizumab compared with docetaxel or nivolumab for the treatment of advanced NSCLC after first-line platinum-doublet chemotherapy. Materials and methods: A three-state partitioned-survival model was developed. Clinical inputs were obtained from the phase III OAK trial comparing atezolizumab with...
Migraine burden and costs in France: a nationwide claims database analysis of triptan users.
Published in Journal of medical economics
Objectives: To estimate the burden of migraine in the population of French patients identified as specific migraine acute treatment users compared to a control group. Methods: A cross-sectional retrospective analysis was performed on the Echantillon Généraliste des Bénéficiaires claims database, a 1/97 random sample of the French public insurance d...
Hospital costs associated with intraoperative hypotension among non-cardiac surgical patients in the US: a simulation mo...
Published in Journal of medical economics
Objective: Recent studies indicate intraoperative hypotension, common in non-cardiac surgical patients, is associated with myocardial injury, acute kidney injury, and mortality. This study extends on these findings by quantifying the association between intraoperative hypotension and hospital expenditures in the US. Methods: Monte Carlo simulations...
Cervical cancer prevention in Morocco: a model-based cost-effectiveness analysis.
Published in Journal of medical economics
Objective: Cervical cancer is a huge public health issue in Morocco which represents the second most frequent and fatal cancer among women. Countries that have not yet introduced the HPV vaccine could benefit greatly, but before implementation it is necessary to perform country-specific economic assessments that include current screening practices....
Guidelines-based treatment associated with improved economic outcomes in nontuberculous mycobacterial lung disease.
Published in Journal of medical economics
Background: The prevalence of nontuberculous mycobacterial lung disease (NTMLD) in the US has increased; however, data characterizing the associated healthcare utilization and expenditure at the national level are limited. Objective: To examine associations between economic outcomes and the use of anti-Mycobacterium avium complex (MAC) guidelines-b...
Estimated annual and lifetime labor productivity in the United States, 2016: implications for economic evaluations.
Published in Journal of medical economics
Background: Human-capital based lifetime productivity estimates are frequently used in cost-of-illness (COI) analyses and, less commonly, in cost-effectiveness analyses (CEAs). Previous US estimates assumed that labor productivity and real earnings both grow by 1% per year. Objectives: This study presents estimates of annual and lifetime productivi...
