Luedke, Catherine Zhao, Yue McCracken, Jenna Maule, Jake Yang, Lian-He Jug, Rachel Galeotti, Jonathan Siddiqi, Imran Gong, Jerald Lu, Chuanyi Mark
...
Published in
Journal of clinical pathology
Myeloid neoplasms occur in the setting of chronic lymphocytic leukaemia (CLL)/CLL-like disease. The underlying pathogenesis has not been elucidated. Retrospectively analysed 66 cases of myeloid neoplasms in patients with CLL/CLL-like disease. Of these, 33 patients (group 1) had received treatment for CLL/CLL-like disease, while the other 33 patient...
Collà Ruvolo, Claudia Würnschimmel, Christoph Wenzel, Mike Nocera, Luigi Califano, Gianluigi Tian, Zhe Shariat, Shahrokh F Saad, Fred Chun, Felix K H Briganti, Alberto
...
Published in
Journal of clinical pathology
To compare the 1973 WHO and the 2004/2016 WHO grading systems in patients with urothelial carcinoma of urinary bladder (UCUB), since no consensus has been made which classification should supersede the other and since both are recommended in clinical practice. Newly diagnosed patients with Ta UCUB treated with transurethral resection of bladder tum...
Nunnari, Josè Graziano, Paolo Muscarella, Lucia Anna Rossi, Antonio Grillo, Lucia Rosalba Montrone, Giuseppe Di Lorenzo, Angela Bronzini, Monica Leone, Alvaro
Published in
Journal of clinical pathology
Diagnostic tumour samples are mandatory for morphologic and molecular diagnosis of non-small cell lung cancer (NSCLC) to establish the best therapeutic approach. In the presence of small tumour tissue sample, the pathologist needs to make responsible choices to achieve a correct diagnosis and save material for subsequent molecular evaluations. Neve...
Ahmed, Syed Salahuddin Lim, Jeffrey Chun Tatt Thike, Aye Aye Iqbal, Jabed Tan, Puay Hoon
Published in
Journal of clinical pathology
Phyllodes tumours (PTs) categorised as benign, borderline and malignant, account for 1% of all breast tumours. Histological assessment does not always predict tumour behaviour, hindering determination of the clinical course and management.Epithelial-mesenchymal transition (EMT) is an important process during embryogenesis. Dysregulation of EMT caus...
Jhala, Hiral Harling, Leanne Rodrigo, Alberto Nonaka, Daisuke Mclean, Emma Ng, Wen Okiror, Lawrence Bille, Andrea
Published in
Journal of clinical pathology
Primary lung adenocarcinoma consists of a spectrum of clinical and pathological subtypes that may impact on overall survival (OS). Our study aims to evaluate the impact of adenocarcinoma subtype and intra-alveolar spread on survival after anatomical lung resection and identify different prognostic factors based on stage and histological subtype. Ne...
Gragnano, Gianluca Nacchio, Mariantonia Sgariglia, Roberta Conticelli, Floriana Iaccarino, Antonino De Luca, Caterina Troncone, Giancarlo Malapelle, Umberto
Published in
Journal of clinical pathology
Whenever tissue sample is not available, non-small cell lung cancer (NSCLC) biomarker testing is performed with liquid biopsy. The Kirsten rat sarcoma viral oncogene homolog (KRAS) p.G12C mutation is a novel target in patients with NSCLC. In this study, 33 NSCLC frozen plasma samples, previously characterised for KRAS mutational status by next gene...
Ericson Lindquist, Kajsa Ciornei, Cristina Westbom-Fremer, Sofia Gudinaviciene, Inga Ehinger, Anna Mylona, Nektaria Urdar, Rodrigo Lianou, Maria Svensson, Franziska Seidal, Tomas
...
Published in
Journal of clinical pathology
Accurate and reliable diagnosis is essential for lung cancer treatment. The study aim was to investigate interpathologist diagnostic concordance for pulmonary tumours according to WHO diagnostic criteria. Fifty-two unselected lung and bronchial biopsies were diagnosed by a thoracic pathologist based on a broad spectrum of immunohistochemical (IHC) ...
Mojica, Wilfrido Cwiklinski, Katherine Jin, Xiaobing Liu, Weiguo Yergeau, Donald
Published in
Journal of clinical pathology
To determine if a simple prewash step added to the processing workflow of tissue procurement by a core needle biopsy device will recover enough cells to expand the laboratory testing armamentarium. Tissue was obtained from unfixed resection specimens using a core needle device and washed in a buffered solution before fixation. This creates a liquid...
Reese, Alexander Margo, Curtis Edward
Published in
Journal of clinical pathology
Conjunctival squamous intraepithelial neoplasia (CSIN) represents the in situ precursor of squamous cell carcinoma. The graded severity of intraepithelial dysplasia is considered a measure of risk for progression to invasive carcinoma. The range of cytoarchitectural changes in CSIN overlaps those of reactive atypia, squamous epithelial papilloma an...
Dignan, Caroline Senior, Adya Gonzalez, Raul S
Published in
Journal of clinical pathology
Epiploic appendages are fatty peritoneal structures on the external surface of the colon that can infarct and become necrotic in situ or autoamputate. To describe clinicopathological features of infarcted epiploic appendages (IEAs). We reviewed 52 IEAs from 49 patients, recording numerous clinical and pathological characteristics, which were compar...
