Sacco, Keith A Smith, Matthew J Bahna, Sami L Buchbinder, David Burkhardt, Joshua Cooper, Megan A Hartog, Nicholas L Kobrynski, Lisa Patel, Kiran P Abraham, Roshini S
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Published in
Journal of clinical immunology
Chronic granulomatous disease (CGD) is an innate immune deficiency, primarily affecting the phagocytic compartment, and presenting with a diverse phenotypic spectrum ranging from severe childhood infections to monogenic inflammatory bowel disease. Dihydrorhodamine (DHR) flow cytometry is the standard diagnostic test for CGD, and correlates with NAD...
Gu, Wei Wen, Dalin Lu, Hongxiang Zhang, Anqiang Wang, Haiyan Du, Juan Zeng, Ling Jiang, Jianxin
Published in
Journal of clinical immunology
miR-608 has been indicated to play an important role in the pathogenesis of various inflammation-related diseases, including sepsis and several types of cancers. However, there is little information about the underlying mechanism, especially in inflammatory cells. In this study, an hsa-miR-608-inhibition cell model was constructed in U937 cells usi...
Bernatowska, Ewa Skomska-Pawliszak, Małgorzta Wolska-Kuśnierz, Beata Pac, Małgorzata Heropolitanska-Pliszka, Edyta Pietrucha, Barbara Bernat-Sitarz, Katarzyna Dąbrowska-Leonik, Nel Bohynikova, Nadia Piątosa, Barbara
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Published in
Journal of clinical immunology
The aim of the study was to estimate the rate of adverse reactions to live BCG Moreau vaccine, manufactured by Biomed in Poland, in severe combined immunodeficiency (SCID) patients. The profiles of 52 SCID patients vaccinated at birth with BCG, hospitalized in Children's Memorial Health Institute, Warsaw (CMHI), in the years 1980-2015 were compared...
Delmonte, Ottavia M Baldin, Fabian Ovchinsky, Nadia Marquardsen, Florian Recher, Mike Notarangelo, Luigi D Kosinski, Slawomir M
Published in
Journal of clinical immunology
Noguchi, Satoko Takekawa, Daiki Saito, Junichi Hashiba, Eiji Hirota, Kazuyoshi
Published in
Journal of clinical immunology
Al-Saud, Bandar Alajlan, Huda Sabar, Haneen Anwar, Siddiq Alruwaili, Hibah Al-Hussain, Turki Alamri, Nada Alazami, Anas M
Published in
Journal of clinical immunology
Marsh, Rebecca A Leiding, Jennifer W Logan, Brent R Griffith, Linda M Arnold, Danielle E Haddad, Elie Falcone, E Liana Yin, Ziyan Patel, Kadam Arbuckle, Erin
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Published in
Journal of clinical immunology
Inflammatory bowel disease (IBD) affects approximately 1/3 of patients with chronic granulomatous disease (CGD). Comprehensive investigation of the effect of allogeneic hematopoietic cell transplantation (HCT) on CGD IBD and the impact of IBD on transplant outcomes is lacking. We collected data retrospectively from 145 patients with CGD who had rec...
Georgiev, Peter Charbonnier, Louis-Marie Chatila, Talal A
Published in
Journal of clinical immunology
Regulatory T (Treg) cells expressing the transcription factor forkhead box P3 (Foxp3) play a requisite role in the maintenance of immunological homeostasis and prevention of peripheral self-tolerance breakdown. Although Foxp3 by itself is neither necessary nor sufficient to specify many aspects of the Treg cell phenotype, its sustained expression i...
Guo, Yanyang Zhu, Zhenlai Gao, Jixin Zhang, Chen Zhang, Xiujun Dang, Erle Li, Wei Qiao, Hongjiang Liao, Wenjun Wang, Gang
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Published in
Journal of clinical immunology
In the past decade, an increasing number of otherwise healthy individuals suffered from invasive fungal infections due to inherited CARD9 mutations. Herein, we present a patient with a homozygous CARD9 mutation who was suffering from localized subcutaneous phaeohyphomycosis caused by the phytopathogenic fungus Pallidocercospora crystallina which ha...
Hoyos-Bachiloglu, Rodrigo Gallo, Silvanna Vizcaya, Cecilia Zuñiga, Pamela Valbuena, José R Casanova, Jean Laurent Bustamante, Jacinta Borzutzky, Arturo
Published in
Journal of clinical immunology
