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Not merely a protective packing organ? A review of fascia and its force transmission capacity.

Published in Journal of applied physiology (Bethesda, Md. : 1985)

Recent research indicates that fascia is capable of changing its biomechanical properties. Moreover, as it links the skeletal muscles, forming a body-wide network of multidirectional myofascial continuity, the classical conception of muscles as independent actuators has been challenged. Hence, the present synthesis review aims to characterize the m...

Enhanced cerebral perfusion during brief exposures to cyclic intermittent hypoxemia.

Published in Journal of applied physiology (Bethesda, Md. : 1985)

Cerebral vasodilation and increased cerebral oxygen extraction help maintain cerebral oxygen uptake in the face of hypoxemia. This study examined cerebrovascular responses to intermittent hypoxemia in eight healthy men breathing 10% O2 for 5 cycles, each 6 min, interspersed with 4 min of room air breathing. Hypoxia exposures raised heart rate ( P

Exercise induces muscle fiber type switching via transient receptor potential melastatin 2 (TRPM2)-dependent Ca2+ signal...

Published in Journal of applied physiology (Bethesda, Md. : 1985)

The aim of the present study was to examine whether transient receptor potential melastatin 2 (TRPM2) plays a role in muscle fiber type transition during exercise. Mice were trained at a speed of 12 m/min at a slope of 0 ° for 60 min 5 consecutive d/wk for 4-wk. Exhaustion tests were performed on the treadmill (the speed was set at 6 m/min at a slo...

Cycling Efficiency and Energy Cost of Walking in Young and Older Adults.

Published in Journal of applied physiology (Bethesda, Md. : 1985)

To determine whether age affects cycling efficiency and the energy cost of walking (Cw), 190 healthy adults, ages 18-81 yr, cycled on an ergometer at 50 W and walked on a treadmill at 1.34 m/s. Ventilation and gas exchange at rest and during exercise were used to calculate net Cw and net efficiency of cycling. Compared to the 18-40 yr age group (2....

Looking beyond macro-ventilatory parameters and re-thinking ventilator-induced lung injury.

Published in Journal of applied physiology (Bethesda, Md. : 1985)

Specific force of the vastus lateralis in adults with Achondroplasia.

Published in Journal of applied physiology (Bethesda, Md. : 1985)

Achondroplasia is a clinical condition defined by shorter stature and disproportionate limb length. Force production in able-bodied individuals (controls) is proportional to muscle size, but given the disproportionate nature of Achondroplasia, normalising to anatomical cross sectional area (ACSA) is inappropriate. The aim of this study was to asses...

The cardiac contraction cycle: Is Ca2+ going local?

Published in Journal of applied physiology (Bethesda, Md. : 1985)

The impact of dairy protein during limb immobilization and recovery on muscle size and protein synthesis; a randomized c...

Published in Journal of applied physiology (Bethesda, Md. : 1985)

Muscle disuse results in the loss of muscular strength and size, due to an imbalance between protein synthesis (MPS) and breakdown (MPB). Protein ingestion stimulates MPS, although it is not established if protein is able to attenuate muscle loss with immobilization (IM) or influence the recovery consisting of ambulatory movement followed by resist...

Skeletal Muscle Function During the Progression of Cancer Cachexia in the Male ApcMin/+ Mouse.

Published in Journal of applied physiology (Bethesda, Md. : 1985)

While cancer-induced skeletal muscle wasting has been widely investigated, the drivers of cancer-induced muscle functional decrements are only beginning to be understood. Decreased muscle function impacts cancer patient quality of life and health status, and several potential therapeutics have failed in clinical trials due to a lack of functional i...

Enhanced muscle blood flow with intermittent pneumatic compression of the lower leg during plantar flexion exercise and ...

Published in Journal of applied physiology (Bethesda, Md. : 1985)

This study tested the hypothesis that intermittent compression of the lower limb would increase blood flow during exercise and post-exercise recovery. Data were collected from 12 healthy individuals (8 men) who performed three minutes of standing plantar flexion exercise. Three conditions were tested: no applied compression (NoComp), compression du...