The aim of the study was to identify stimulation conditions permitting the occurrence of extra-torque (ET) and to examine their impact on spinal and corticospinal excitabilities. Twelve subjects received stimulation trains over the tibial nerve (20 sec duration, 1ms pulse duration) that were delivered at three stimulation frequencies (20, 50 and 10...
Published in Journal of applied physiology (Bethesda, Md. : 1985)
One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that occurs in response to resistance exercise. A large body of work shows that a mTORC1-mediated increase of muscle protein synthesis is the key, but not sole, mechanism by which resistance exercise causes muscle hypertrophy. Whilst much of the hypertrophy signalin...
Published in Journal of applied physiology (Bethesda, Md. : 1985)
Regular exercise-induced acute inflammatory responses are suggested to improve the inflammatory profile and insulin sensitivity. As body temperature elevations partly mediate this response, passive heating might be a viable tool to improve the inflammatory profile. This study investigated the acute, and chronic effects of hot water immersion on inf...
Published in Journal of applied physiology (Bethesda, Md. : 1985)
Sprint interval training (SIT) combined with post-exercise blood-flow restriction (BFR) is a novel method to increase maximal oxygen uptake (V̇O2max) in trained individuals, and also provides a potent acute stimulus for angiogenesis and mitochondrial biogenesis. The efficacy to enhance endurance performance has however yet to be demonstrated. 21 tr...
Published in Journal of applied physiology (Bethesda, Md. : 1985)
We examined the impact of serotonin (5HT) on the frequency and duration of central apneic events, and the frequency of accompanying arousals, during non-rapid and rapid eye movement (NREM and REM) sleep across the light-dark cycle. Electroencephalography, electromyography, core body temperature and activity were recorded for 24 hours following impl...
Published in Journal of applied physiology (Bethesda, Md. : 1985)
Published in Journal of applied physiology (Bethesda, Md. : 1985)
Carnosine and anserine are dipeptides synthesized from histidine and β-alanine by carnosine synthase (ATPGD1). These dipeptides, present in high concentration in the skeletal muscle, form conjugates with lipid peroxidation products such as 4-hydroxy trans-2-nonenal (HNE). Although skeletal muscle levels of these dipeptides could be elevated by feed...
Published in Journal of applied physiology (Bethesda, Md. : 1985)
Cancer patients with a history of anticancer chemotherapy are at an increased cardiovascular disease risk compared with cancer-free populations. Therefore, we tested the hypothesis that cancer patients receiving adjuvant chemotherapy would have a lower cutaneous microvascular reactivity and lower endothelium-dependent flow-mediated dilation (FMD) o...
Published in Journal of applied physiology (Bethesda, Md. : 1985)
Autonomic control of blood pressure (BP) and heart rate (HR) is crucial during bleeding and hemorrhagic shock (HS) to compensate for hypotension and hypoxia. Previous works have observed that at the point of hemodynamic decompensation a marked suppression of BP and HR variability occurs, leading to irreversible shock. We hypothesized that recovery ...
The aim of the present study was to compare the development and etiology of neuromuscular fatigue of the knee extensor (KE) and plantar flexor (PF) muscles during repeated maximal voluntary isometric contractions (MVIC) between children and adults. Twenty-one prepubertal boys (9-11 years) and 24 men (18-30 years) performed two fatigue protocols con...
