Correction of acknowledgments: PD-L1 testing in non-small cell lung cancer: past, present, and future.
Published in Journal of pathology and translational medicine
Adjunctive markers for classification and diagnosis of central nervous system tumors: results of a multi-center neuropat...
Published in Journal of Pathology and Translational Medicine
Background The revised 4th 2016 World Health Organization (WHO) classification of tumors of the central nervous system (CNS) classification has adopted integrated diagnosis encompassing the histology and molecular features of CNS tumors. We aimed to investigate the immunohistochemistry, molecular testing, and testing methods for diagnosis of CNS tu...
Introduction to digital pathology and computer-aided pathology
Published in Journal of Pathology and Translational Medicine
Digital pathology (DP) is no longer an unfamiliar term for pathologists, but it is still difficult for many pathologists to understand the engineering and mathematics concepts involved in DP. Computer-aided pathology (CAP) aids pathologists in diagnosis. However, some consider CAP a threat to the existence of pathologists and are skeptical of its c...
Double cocktail immunostains with high molecular weight cytokeratin and GATA-3: useful stain to discriminate in situ inv...
Published in Journal of Pathology and Translational Medicine
Background Distinguishing prostatic stromal invasion (PSI) by urothelial carcinoma (UC) from in situ UC involving prostatic ducts or acini with no stromal invasion (in situ involvement) may be challenging on hematoxylin and eosin stained sections. However, the distinction between them is important because cases with PSI show worse prognosis. This s...
Programmed death-ligand 1 expression and its correlation with clinicopathological parameters in gallbladder cancer
Published in Journal of Pathology and Translational Medicine
Background Immunomodulatory therapies targeting the interaction between programmed cell death protein 1 and programmed death-ligand 1 (PD-L1) have become increasingly important in anticancer treatment. Previous research on the subject of this immune response has established an association with tumor aggressiveness and a poor prognosis in certain ca...
Morphologic variant of follicular lymphoma reminiscent of hyaline-vascular Castleman disease
Published in Journal of Pathology and Translational Medicine
Follicular lymphoma (FL) with hyaline-vascular Castleman disease (FL-HVCD)-like features is a rare morphologic variant, with fewer than 20 cases in the literature. Herein, we report a case of FL-HVCD in a 37-year-old female who presented with isolated neck lymph node enlargement. The excised lymph node showed features reminiscent of HVCD, including...
Contribution of cytologic examination to diagnosis of poorly differentiated thyroid carcinoma
Published in Journal of Pathology and Translational Medicine
Background The cytologic diagnosis of poorly differentiated thyroid carcinoma (PDTC) is difficult because it lacks salient cytologic findings and shares cytologic features with more commonly encountered neoplasms. Due to diverse cytologic findings and paucicellularity of PDTC, standardization of cytologic diagnostic criteria is limited. The purpose...
Pseudomesotheliomatous carcinoma of the lung in the parietal pleura
Published in Journal of Pathology and Translational Medicine
Colorectal epithelial neoplasm associated with gut-associated lymphoid tissue
Published in Journal of Pathology and Translational Medicine
Background Colorectal epithelial neoplasm extending into the submucosal gut-associated lymphoid tissue (GALT) can cause difficulties in the differential diagnosis. Regarding GALT-associated epithelial neoplasms, a few studies favor the term “GALT carcinoma” while other studies have mentioned the term “GALT-associated pseudoinvasion/epithelial mispl...
Papillary thyroid carcinoma variants with tall columnar cells
Published in Journal of Pathology and Translational Medicine
