Park, Ji Hyun Cha, Yoon Jin Seo, Ja Yeong Lim, Jae Yol Hong, Soon Won
Published in
Journal of Pathology and Translational Medicine
Background Before publication of the new classification system named the Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) in 2018, there was no standard classification for salivary gland lesions obtained by fine-needle aspiration (FNA). We therefore aimed to evaluate the diagnostic utility of this system by retrospectively reviewing...
Joo, Mee Kim, Nam-Hoon
Published in
Journal of pathology and translational medicine
Crystal-storing histiocytosis (CSH) is a rare entity that is characterized by intrahistiocytic accumulation of crystallized immunoglobulins. CSH is not a malignant process per se, but the majority of CSH cases are associated with underlying lymphoproliferative disorder. Although CSH can occur in a variety of organs, gastric CSH is very rare. We pre...
Kim, Kwang-kyoun Park, Young-wook Kim, Tae-hyeong Seo, Kyung-deok
Published in
Journal of Pathology and Translational Medicine
Of the drugs developed to prevent and treat osteoporosis, bisphosphonate has played a very important role in preventing osteoporotic fractures. However, case reports describing atypical femoral fractures in patients using long-term bisphosphonates have emerged. The majority of atypical femur fractures occurs in the lateral aspect of the subtrochant...
Kim, Jung Ho Kang, Gyeong Hoon
Published in
Journal of Pathology and Translational Medicine
Here, we provide an up-to-date review of the histopathology and molecular pathology of serrated colorectal lesions. First, we introduce the updated contents of the 2019 World Health Organization classification for serrated lesions. The sessile serrated lesion (SSL) is a new diagnostic terminology that replaces sessile serrated adenoma and sessile s...
Bae, Jeong Mo Yoo, Seung-Yeon Kim, Jung Ho Kang, Gyeong Hoon
Published in
Journal of Pathology and Translational Medicine
Recent advances in immuno-oncology have increased understanding of the tumor immune microenvironment (TIME), and clinical trials for immune checkpoint inhibitor treatment have shown remission and/or durable response in certain proportions of patients stratified by predictive biomarkers. The TIME in colorectal cancer (CRC) was initially evaluated se...
Sung, Yeoun Eun Cho, Uiju Lee, Kyo Young
Published in
Journal of Pathology and Translational Medicine
Background Squamous cell carcinomas (SqCCs) of the lung are known to arise more often in a central area but reports of peripheral SqCCs have increased, with a pathogenesis that is obscured. In this study, the clinicopathologic characteristics of peripheral lung SqCCs were studied and compared with those of the central type. Methods This study inclu...
Kim, Sue Youn Kim, Taeeun Kim, Kwangsoon Bae, Ja Seong Kim, Jeong Soo Jung, Chan Kwon
Published in
Journal of Pathology and Translational Medicine
Background The presence of telomerase reverse transcriptase ( TERT ) promoter mutations have been associated with a poor prognosis in patients with papillary thyroid carcinomas (PTC). The frequency of TERT promoter mutations varies widely depending on the population and the nature of the study. Methods Data were prospectively collected in 724 conse...
Jung, Chan Kwon Park, So Yeon Kim, Jang-Hee Kakudo, Kennichi
Published in
Journal of Pathology and Translational Medicine
Kim, Eun-Kyu Park, So Yeon Kim, Sung-Won
Published in
Journal of Pathology and Translational Medicine
BRCA1/2 germline mutations account for the majority of hereditary breast cancers. Since the identification of the BRCA genes, several attempts have been made to define the clinicopathological characteristics of BRCA -associated breast cancer in comparison with sporadic breast cancer. Asians constitute 60% of the world population, and although the i...
Ramakrishna, Banumathi Yewale, Rohan Vijayakumar, Kavita Radhakrishna, Patta Ramakrishna, Balakrishnan Siddartha
Published in
Journal of pathology and translational medicine
IgG4-related disease of the stomach is a rare disorder, and only a few cases have been reported. We present two cases that were identified over a 2-month period in our center. Two male patients aged 52 and 48 years presented with mass lesion in the stomach, which were clinically thought to be gastrointestinal stromal tumor, and they underwent excis...
