Determinants of response to repeat hepatitis B vaccination in HIV-infected prior non-responders
Published in Journal of Infection
Antibiotic prophylaxis in hematopoietic stem cell transplantation. A meta-analysis of randomized controlled trials.
...Published in Journal of Infection
ObjectivesWe performed a meta-analysis to evaluate the impact of systemic antibiotic prophylaxis in hematopoietic stem cell transplantation (HSCT) recipients. MethodsWe collected reports from PubMed, the Cochrane Library, EMBASE, CINAHL, and Web of Science, along with references cited therein. We included prospective, randomized studies on systemic...
Antibiotic prophylaxis for preventing recurrent cellulitis: A systematic review and meta-analysis
Published in Journal of Infection
ImportanceA significant proportion of patients who have had a first episode of erysipelas or uncomplicated cellulitis will subsequently develop a recurrence. There is disagreement about how effective antibiotic prophylaxis is for preventing recurrent cellulitis. ObjectiveTo determine if antibiotic prophylaxis is effective in preventing recurrent ce...
Editorial Board
Published in Journal of Infection
IP-10 detection in urine is associated with lung diseases
Published in BMC Infectious Diseases
Backgroundblood cytokines and chemokines have been proposed as biomarkers for tuberculosis (TB). Recently, some immune mediators found in the urine of patients with renal dysfunctions have also been suggested as potential biomarkers. Finding biomarkers for TB in urine would present several advantages over blood in terms of collection and safety. Th...
A prospective longitudinal study evaluating the usefulness of the interferon-gamma releasing assay for predicting active...
...Published in Journal of Infection
ObjectiveThere is little information on the efficacy of interferon-gamma-releasing assays for predicting subsequent active tuberculosis in hematopoietic stem cell transplant (HCT) recipients. MethodsWe prospectively enrolled adult patients admitted for allogeneic HCT during a 3-year period in an intermediate-tuberculosis-burden country. All the pat...
Estimated prevalence of chronic Q fever among Coxiella burnetii seropositive patients with an abdominal aortic/iliac ane...
Published in Journal of Infection
ObjectivesThe aim of this study was to estimate the seroprevalence of Q fever and prevalence of chronic Q fever in patients with abdominal aortic and/or iliac disease after the Q fever outbreak of 2007–2010 in the Netherlands. MethodsIn November 2009, an ongoing screening program for Q fever was initiated. Patients with abdominal aortic and/or ilia...
Regulatory T cell response correlates with the severity of human hantavirus infection
Published in Journal of Infection
ObjectivesHantaviruses are an important group of emerging zoonotic pathogens, with significant mortality rates. Immunopathology is thought to be important in hantaviral disease, but the balance between protective and harmful responses is unknown. We studied Puumala hantavirus (PUUV) infection, which causes hemorrhagic fever with renal syndrome (HFR...
Cerebrospinal fluid complement activation in patients with pneumococcal and meningococcal meningitis
Published in Journal of Infection
BackgroundRecent research into the treatment of bacterial meningitis has examined the innate immune system, specifically the complement system, as a potential target for adjuvant therapy. However, the effects of blocking the complement system may be pathogen dependent. MethodsWe measured cerebrospinal fluid (CSF) levels of complement components C1q...
Colistin is relatively safe in hematological malignancies and hematopoietic stem cell transplantation patients
Published in Infection
PurposeColistin is increasingly used as the last-resort treatment option against infections caused by multidrug-resistant (MDR) Gram-negative pathogens, but its nephrotoxicity is of concern, especially in severely ill patients. The aim of this study was to analyze the toxicity of colistin therapy in adults and children with hematological malignanci...
