Sultan, Menbeu Zewdie, Ayalew Priyadarshani, Dilanthi Hassen, Ephrem Tilahun, Melkamu Geremew, Tigist Beane, Abi Haniffa, Rashan Berenholtz, Sean M Checkley, William
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Published in
Journal of critical care
Intensive care units (ICUs) in low- and middle-income countries have high mortality rates, and clinical data are needed to guide quality improvement (QI) efforts. This study utilizes data from a validated ICU registry specially developed for resource-limited settings to identify evidence-based QI priorities for ICUs in Ethiopia. A retrospective coh...
Tirupakuzhi Vijayaraghavan, Bharath Kuma... Rashan, Aasiyah Ranganathan, Lakshmi Venkataraman, Ramesh Tripathy, Swagata Jayakumar, Devachandran Ramachandran, Pratheema Mohamed, Zubair Umer Balakrishnan, Sindhu Ramakrishnan, Nagarajan
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Published in
Journal of Critical Care
• There is limited information on frailty and its impact on outcomes from India and other lower-middle income countries. • In this registry-embedded cohort study that enrolled 838 patients from 4 ICUs in India, prevalence of frailty was 20%. • Frailty was associated with higher ICU mortality, hospital mortality and receipt of organ support.
Lannon, Melissa Duda, Taylor Greer, Alisha Hewitt, Mark Sharma, Arjun Martyniuk, Amanda Owen, Julian Amin, Faizan Sharma, Sunjay
Published in
Journal of critical care
Extracorporeal membrane oxygenation (ECMO) is routinely used in patients with severe respiratory failure and has been increasingly needed during the COVID-19 pandemic. In patients treated with ECMO, significant intracranial hemorrhage (ICH) risk exists due to circuit characteristics, anticoagulation, and disease characteristics. ICH risk may be sub...
Camporota, Luigi Sanderson, Barnaby Worrall, Stephanie Ostermann, Marlies Barrett, Nicholas A Retter, Andrew Busana, Mattia Collins, Patrick Romitti, Federica Hunt, Beverley J
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Published in
Journal of critical care
Despite its diagnostic and prognostic importance, physiologic dead space fraction is not included in the current ARDS definition or severity classification. ARDS caused by COVID-19 (C-ARDS) is characterized by increased physiologic dead space fraction and hypoxemia. Our aim was to investigate the relationship between dead space indices, markers of ...
Reyes, Luis Felipe Garcia-Gallo, Esteban Murthy, Srinivas Fuentes, Yuli V Serrano, Cristian C Ibáñez-Prada, Elsa D Lee, James Rojek, Amanda Citarella, Barbara Wanjiru Gonçalves, Bronner P
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Published in
Journal of critical care
To determine its cumulative incidence, identify the risk factors associated with Major Adverse Cardiovascular Events (MACE) development, and its impact clinical outcomes. This multinational, multicentre, prospective cohort study from the ISARIC database. We used bivariate and multivariate logistic regressions to explore the risk factors related to ...
Doidge, James C Yarnell, Christopher J
Published in
Journal of critical care
Cheema, Muhammad Rafay Shahzad
Published in
Journal of critical care
Krishnan, Jamuna K Schenck, Edward J
Published in
Journal of critical care
Estoos, Ethan M Jocham, Kevin P Zhang, Chengda Benson, Lauren M Milas, Anamaria Zakhary, Bishoy
Published in
Journal of critical care
While mechanical ventilation practices on venovenous extracorporeal membrane oxygenation (VV ECMO) are variable, most institutions utilize a lung rest strategy utilizing relatively low positive end-expiratory pressure (PEEP). The effect of PEEP titration using esophageal manometry during VV ECMO on pulmonary and cardiac function is unknown. This wa...
Milano, Victoria Hurt, Jacob Nielsen, Nathan D.
Published in
Journal of Critical Care