Park, Jin-Myeong Park, Jung Hag
Published in
Journal of Chromatography A
Phosphated β-cyclodextrin (PCD)-coated zirconia monolith was used as the chiral stationary phase in capillary electrochromatography (CEC) for separation of four basic chiral compounds including metoprolol (MET), sertraline (SER), citalopram (CIT) and atenolol (ATE). Migration, chiral selectivity and resolution data were measured in reversed-phase m...
Herrero, Pol Borrull, Francesc Pocurull, Eva Marcé, Rosa M.
Published in
Journal of Chromatography A
A Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) extraction method followed by liquid chromatography-(Orbitrap) high resolution mass spectrometry was developed for the simultaneous determination of five benzotriazole, four benzothiazole and five benzenesulfonamide derivates in sewage sludge. While the method was being developed, several ...
Dhadge, Vijaykumar L. Rosa, Sara A.S.L. Azevedo, Ana Aires-Barros, Raquel Roque, Ana C.A.
Published in
Journal of Chromatography A
The potential to combine aqueous two-phase extraction (ATPE) with magnetic separation was here investigated with the aim of developing a selective non-chromatographic method for the purification of antibodies from cell culture supernatants. Aqueous two-phase systems (ATPS) composed of polyethylene glycol (PEG) and dextran were supplemented with sev...
Bouchet, Sylvain Björn, Erik
Published in
Journal of Chromatography A
The behavior of monomethylmercury (MMHg) is markedly influenced by its distribution among complexes with low molecular mass (LMM) thiols but analytical methodologies dedicated to measure such complexes are very scarce up to date. In this work, we selected 15 LMM thiols often encountered in living organisms and/or in the environment and evaluated th...
Casado, J. Rodríguez, I. Ramil, M. Cela, R.
Published in
Journal of Chromatography A
The suitability of mixed-mode (reversed-phase and cationic exchange) solid-phase extraction (SPE) for the selective concentration of basic antimycotic drugs (belonging to triazole, imidazole and allylamine chemical classes) in environmental water samples has been demonstrated for first time. The use of a sequential elution protocol, allowing the re...
Islam, Tuhidul Aguilar-Yañez, José Manuel Simental-Martínez, Jesús Ortiz-Alcaraz, Cesar Ivan Rito-Palomares, Marco Fernandez-Lahore, Marcelo
Published in
Journal of Chromatography A
In recent years, affinity fusion-tag systems have become a popular technique for the purification of recombinant proteins from crude extracts. However, several drawbacks including the high expense and low stability of ligands, their leakage during operation, and difficulties in immobilization, make it important to further develop the method. The pr...
Duan, Li Guo, Long Liu, Ke Liu, E.-Hu Li, Ping
Published in
Journal of Chromatography A
Citrus herbs have been widely used in traditional medicine and cuisine in China and other countries since the ancient time. However, the authentication and quality control of Citrus herbs has always been a challenging task due to their similar morphological characteristics and the diversity of the multi-components existed in the complicated matrix....
Orlandini, S. Pasquini, B. Stocchero, M. Pinzauti, S. Furlanetto, S.
Published in
Journal of Chromatography A
The development of a capillary electrophoresis (CE) method for the assay of almotriptan (ALM) and its main impurities using an integrated Quality by Design and mixture-process variable (MPV) approach is described. A scouting phase was initially carried out by evaluating different CE operative modes, including the addition of pseudostationary phases...
Grand-Guillaume Perrenoud, Alexandre Veuthey, Jean-Luc Guillarme, Davy
Published in
Journal of Chromatography A
The recent market release of a new generation of supercritical fluid chromatography (SFC) instruments compatible with state-of-the-art columns packed with sub-2μm particles (UHPSFC) has contributed to the reemergence of interest in this technology at the analytical scale. However, to ensure performance competitiveness of this technique with modern ...
Alvarez-Rivera, Gerardo Vila, Marlene Lores, Marta Garcia-Jares, Carmen Llompart, Maria
Published in
Journal of Chromatography A
A simple methodology based on solid-phase microextraction (SPME) followed by gas chromatography–tandem mass spectrometry (GC–MS/MS) has been developed for the simultaneous analysis of different classes of preservatives including benzoates, bronidox, 2-phenoxyethanol, parabens, BHA, BHT and triclosan in cosmetic products. In situ acetylation and sub...
