Published in International journal of psychiatry in clinical practice
The case of a man originally diagnosed as having a personality disorder is presented. Follow-up over many years revealed that he was really suffering from a bipolar manic-depressive disorder which responded well to lithium. His later life was characterized by stability.
Published in International journal of psychiatry in clinical practice
The potential efficacy and tolerability of new antidepressants can best be assessed through randomized controlled trials (RCTs). However, the patient population in antidepressant studies is a highly selected group, so the results from such studies may not be applicable to routine clinical practice. This paper describes a questionnaire survey of sen...
Published in International journal of psychiatry in clinical practice
We present evidence that scores on the Montgomery, Hamilton and Beck depression scales are strongly intercorrelated and can be equated to each other. These scales were administered on 107 occasions to patients with major depression. The correlations between scores on each scale were much higher than has been previously reported and, furthermore, th...
Published in International journal of psychiatry in clinical practice
Organic Psychiatry: Psychological Consequences of Cerebral Disorder. 3rd edition: William Alwyn Lishman Oxford: Blackwell Science. 1997. Pp 922. £89.50 (Hardback) (ISBN 0-86542-842-5) £55.00 (Paperback) (ISBN 0-86542-820-4) Psychopharmacology of Antidepressants: Stephen M Stahl London: Martin Dunitz. 1997. Pp 114. Paperback £12.95 (ISBN 1-85317-513...
Published in International journal of psychiatry in clinical practice
Published in International journal of psychiatry in clinical practice
The authors present an overview of drugs that operate on the basis of the cholinergic hypothesis, either currently available for the palliative treatment of Alzheimer's disease or in the later stages of clinical development. Of the many conceivable strategies that are being exploited, only inhibitors of acetylcholinesterase have been shown to have ...
Published in International journal of psychiatry in clinical practice
During the last 30 years there has been renewed clinical interest in the state of 'lack of pleasure' (anhedonia) seen in conditions such as schizophrenia and depression. In spite of some important work, confusion still remains about the term, behaviours and explanatory concepts pertaining to anhedonia. This paper reviews the clinical and basic scie...
Published in International journal of psychiatry in clinical practice
It is not clear why brain CT continues to be used in psychiatric patients in spite of reports of a low yield of useful information. Hypoihetically, in circumstances (such as in Israel) where access to CT is more limited, clinicians will use brain CT more judiciously, resulting in a higher yield. To test this hypothesis, we retrieved and reviewed br...
Published in International journal of psychiatry in clinical practice
Published in International journal of psychiatry in clinical practice
Social phobia is a serious condition in the range of anxiety disorders which, until quite recently, has not been given due attention in research. In this paper we compare existing studies and follow-up results of behaviour therapy and pharmacotherapy. We have endeavoured to work out an effective therapy for this serious condition. Apart from psycho...
