López, Alberto J Hecking, Julia K White, André O
Published in
International journal of molecular sciences
Long-term memory formation requires coordinated regulation of gene expression and persistent changes in cell function. For decades, research has implicated histone modifications in regulating chromatin compaction necessary for experience-dependent changes to gene expression and cell function during memory formation. Recent evidence suggests that an...
Iadarola, Paolo Viglio, Simona
Published in
International journal of molecular sciences
This Special Issue, "Mass Spectrometric Proteomics 2 [...].
Fu, Lingjuan Shi, Jinping Meng, Quanlu Tang, Zhixiong Liu, Ting Zhang, Quanwei Cheng, Shuru
Published in
International journal of molecular sciences
Intramuscular fat (IMF) is vital for meat tenderness and juiciness. This study aims to explore the IMF deposition mechanism and the related molecular markers in sheep. Two populations, Small-tail Han Sheep (STH) and STH × Suffolk (SFK) F1 (SFK × STH), were used as the research object. Histological staining techniques compared the differences in the...
Wang, Dan An, Bang Luo, Hongli He, Chaozu Wang, Qiannan
Published in
International journal of molecular sciences
Anthracnose, induced by Colletotrichum gloeosporioides, poses a substantial economic threat to rubber tree yields and various other tropical crops. Ede1, an endocytic scaffolding protein, plays a crucial role in endocytic site initiation and maturation in yeast. Metacaspases, sharing structural similarities with caspase family proteases, are essent...
Fu, Hengfei Xiao, Guipeng Yang, Zhende Hu, Ping
Published in
International journal of molecular sciences
Pheromone-binding proteins (PBPs) are specific odorant-binding proteins that can specifically recognize insect pheromones. Through transcriptional analysis of the antennae of adult Endoclita signifer, EsigPBP3 was discovered and identified, and EsigPBP3 was found to be highly expressed in the antennae of male moths. Based on the binding characteris...
Petterson, Jennie Mustafa, Dyar Bandaru, Sashidar Eklund, Ella Äng Hallqvist, Andreas Sayin, Volkan I Gagné, Andréanne Fagman, Henrik Akyürek, Levent M
Published in
International journal of molecular sciences
Pulmonary adenocarcinoma (ADC) is a very diverse disease, both genetically and histologically, which displays extensive intratumor heterogeneity with numerous acquired mutations. ADC is the most common type of lung cancer and is believed to arise from adenocarcinoma in situ (AIS) which then progresses to minimally invasive adenocarcinoma (MIA). In ...
Kim, Soon-Bin Hwang, Soonjae Cha, Ji-Young Lee, Ho-Jae
Published in
International journal of molecular sciences
Programmed death ligand 1 (PD-L1) plays a pivotal role in cancer immune evasion and is a critical target for cancer immunotherapy. This review focuses on the regulation of PD-L1 through the dynamic processes of ubiquitination and deubiquitination, which are crucial for its stability and function. Here, we explored the intricate mechanisms involving...
Yamashita, Toru Abe, Koji
Published in
International journal of molecular sciences
The brain is susceptible to oxidative stress, which is associated with various neurological diseases. Edaravone (MCI-186, 3-methyl-1 pheny-2-pyrazolin-5-one), a free radical scavenger, has promising effects by quenching hydroxyl radicals (∙OH) and inhibiting both ∙OH-dependent and ∙OH-independent lipid peroxidation. Edaravone was initially develope...
Dong, Yiming Wang, Jianfeng Yang, Chenteng Bao, Junxia Liu, Xia Chen, Hao Zhang, Xiaojing Shi, Weibo Zhang, Lihua Qi, Qian
...
Published in
International journal of molecular sciences
Coronary artery spasm (CAS) plays an important role in the pathogeneses of various ischemic heart diseases and has gradually become a common cause of life-threatening arrhythmia. The specific molecular mechanism of CAS has not been fully elucidated, nor are there any specific diagnostic markers for the condition. Therefore, this study aimed to exam...
Révész, Csaba Kaucsár, Tamás Godó, Mária Bocskai, Krisztián Krenács, Tibor Mócsai, Attila Szénási, Gábor Hamar, Péter
Published in
International journal of molecular sciences
Upregulation of free radical-generating NADPH oxidases (NOX), xanthine oxidoreductase (XOR), and neutrophil infiltration-induced, NOX2-mediated respiratory burst contribute to renal ischemia-reperfusion injury (IRI), but their roles may depend on the severity of IRI. We investigated the role of NOX, XOR, and neutrophils in developing IRI of various...
