Zielonke, Nadine Kregting, Lindy M Heijnsdijk, Eveline A M Veerus, Piret Heinävaara, Sirpa McKee, Martin de Kok, Inge M C M de Koning, Harry J van Ravesteyn, Nicolien T
Published in
International journal of cancer
Currently, all European countries offer some form of breast cancer screening. Nevertheless, disparities exist in the status of implementation, attendance and the extent of opportunistic screening. As a result, breast cancer screening has not yet reached its full potential. We examined how many breast cancer deaths could be prevented if all European...
Wang, Xiaodong Yu, Bingying Cao, Birong Zhou, Ji Deng, Yongqiang Wang, Zhulin Jin, Guangyi
Published in
International journal of cancer
In recent years, inhibitors of the BET bromodomain proteins, such as BRD4 inhibitors, have demonstrated robust antitumor activity. JQ-1, a representative small molecular BRD4 inhibitor, is also effective to block PD-1/PD-L1 signaling by significantly decreasing the PD-L1 expression on tumor cells. However, toxicity of BRD4 inhibitors on lymphoid an...
Jabagi, Marie Joelle Vey, Norbert Goncalves, Anthony Le Tri, Thien Zureik, Mahmoud Dray-Spira, Rosemary
Published in
International journal of cancer
Our study aimed to analyze the risk of hematologic malignancies (HM) associated with the use of G-CSF with chemotherapy for BC. Using the French National Health Data System, we examined the HM risks in patients diagnosed with an incident breast cancer between 2007 and 2015, who received chemotherapy for BC. Main outcomes were acute myeloid leukemia...
Fan, Fuli Yoo, Hyeon Joo Stock, Sophia Wang, Lei Liu, Yibin Schubert, Maria-Luisa Wang, Sanmei Neuber, Brigitte Hückelhoven-Krauss, Angela Gern, Ulrike
...
Published in
International journal of cancer
Chimeric antigen receptor T (CART) cells targeting CD19 have shown promising results in the treatment of chronic lymphocytic leukemia (CLL). However, efficacy seems to be inferior compared to diffuse large B-cell lymphoma or acute lymphoblastic leukemia. Impaired T-cell fitness of CLL patients may be involved in treatment failure. Less-differentiat...
Kalloger, Steve E Karasinska, Joanna M Keung, Martin S Thompson, Danielle L Ho, Julie Chow, Christine Gao, Dongxia Topham, James T Warren, Cassia Wong, Hui-Li
...
Published in
International journal of cancer
The mixture of epithelial and stromal components in pancreatic ductal adenocarcinoma (PDAC) may confound sequencing-based studies of tumor gene expression. Virtual microdissection has been suggested as a bioinformatics approach to segment the aforementioned components, and subsequent prognostic gene sets have emerged from this research. We examined...
Tian, Yehong Qiu, Xiaowei Wang, Chengxiang Zhao, Jianxin Jiang, Xin Niu, Wenquan Huang, Jinchang Zhang, Fengyu
Published in
International journal of cancer
Evidence is mounting to indicate that cancer patients may have more likelihood of having coronavirus disease 2019 (COVID-19) but lack consistency. A robust estimate is urgently needed to convey appropriate information to the society and the public, in the time of ongoing COVID-19 pandemic. We performed a systematic review and meta-analysis through ...
Watanabe, Yoshiyuki Oikawa, Ritsuko Kodaka, Yasuhiro Sato, Yoshinori Ono, Shoko Kenmochi, Takeshi Suzuki, Hideo Futagami, Seiji Kato, Mototsugu Yamamoto, Hiroyuki
...
Published in
International journal of cancer
Helicobacter pylori (H. pylori) are a primary factor in the pathogenesis of gastric cancer (GC); GC ranks third among cancer-related mortality. A clear understanding of the H. pylori genome factors underlying GC is necessary to develop more effective methods to prevent GC. A single-molecule real-time DNA sequencing-based H. pylori genome-wide assoc...
Zhao, Longgang Zhang, Xuehong
Published in
International journal of cancer
Takada, Kentaro Aizawa, Yoshihiro Sano, Daisuke Okuda, Ryo Sekine, Keisuke Ueno, Yasuharu Yamanaka, Shoji Aoyama, Jun Sato, Kaname Kuwahara, Tatsu
...
Published in
International journal of cancer
To generate a reliable preclinical model system exhibiting the molecular features of salivary adenoid cystic carcinoma (ACC) whose biology is still unclear due to the paucity of stable cell cultures. To develop new in vitro and in vivo models of ACC, the techniques of organoid culture and patient-derived tumor xenograft (PDX), which have attracted ...
Lameijer, Joost R C Nederend, Joost Voogd, Adri C Tjan-Heijnen, Vivianne C G Duijm, Lucien E M
Published in
International journal of cancer
Our study was performed to determine the frequency of recall for bilateral breast lesions at screening mammography and compare its outcome with respect to unilateral recall. We included 329 132 screening mammograms (34 889 initial screens and 294 243 subsequent screens) from a Dutch screening mammography program between January 2013 and January 201...