Zhang, Jun Wang, Runpei Wang, Haili Li, Yuping Zhang, Hongying Dong, Lun Zhang, Hengzhu
Published in
International Journal of Clinical and Experimental Pathology
Activation likelihood estimation meta-analysis was performed to examine the activation characteristics of cognition-related brain regions in patients with mild traumatic brain injury (mTBI). The databases PubMed, Ovid, Cochrane Library, Google Scholar, CNKI, WFSD, and VIP were systematically searched. The software Ginger-ALE 3.0.2 was used for coor...
Zhai, Yuefang Zhu, Zhengtai Li, Hua Zhao, Chunzhi Huang, Yujing Wang, Peng
Published in
International Journal of Clinical and Experimental Pathology
Objective: To quantify the expression of miR-195 and miR-497 in acute stroke and to evaluate their correlations with post-stroke cognitive impairment. Methods: A total of 108 patients with acute stroke admitted to our hospital from January, 2019 to June, 2020 were enrolled as a patient group, and 76 healthy volunteers were recruited as a normal gro...
Lin, Tianqi Yang, Yun Ye, Xiaohong Yao, Jiayue Zhou, Hu
Published in
International Journal of Clinical and Experimental Pathology
Objective: Dysfunctions of microRNAs have been implicated in the progression of clear cell renal cell carcinoma (ccRCC). Here, we investigated the roles of miR-99b and miR-99b* in ccRCC development. Methods: The expression levels of miR-99b and miR-99b* in tumor and tumor-adjacent tissues from ccRCC patients were quantified by quantitative Real-Tim...
Liu, Ling Huang, Yuge Zeng, Cizheng
Published in
International Journal of Clinical and Experimental Pathology
Rosai-Dorfman disease (RDD) is a benign, rare histiocytic disorder presenting as a wide clinical spectrum, which mainly affects bilateral dilated lymph node enlargement. This study aimed to show an infantile RDD and review the clinicopathologic features, imaging, and histological features of RDD, including pitfalls in diagnosis. We report here an i...
Aksionau, Aliaksandr Wei, Eric X
Published in
International Journal of Clinical and Experimental Pathology
Hemophagocytic lymphohistiocytosis, also known as a hemophagocytic syndrome, is a life-threatening condition that can develop in critically ill patients with malignancies, severe infections, during chemotherapy, and may be associated with currently known or unknown genetic abnormalities; however, this list of potential causes can be extensive. The ...
Chen, Zheng Wu, Miaoxing Liu, Jiahua
Published in
International Journal of Clinical and Experimental Pathology
Kelch-like protein 14 (KLHL14) belongs to the Kelch gene family, which interacts with TorsinA and is associated with dystonia symptoms. However, the effect of KLHL14 on tumorigenesis remains unclear; thus, we aimed to explore the effects of KLHL14 on ovarian cancer cells. By analyzing information regarding ovarian cancer patients obtained from The ...
Zheng, Hong Yang, Changjun Tang, Jiansheng
Published in
International Journal of Clinical and Experimental Pathology
Objective: The objective of this study was to investigate the effect on the proliferation, invasion, and apoptosis of bladder cancer cells through miR-502-5p of the Circ_0000735 circular RNA. Methods: Circ_0000735 and miR-502-5p expression of bladder cancer patients in malignant and paracancerous tissues was identified using qRT-PCR. Nucleoplasm is...
Zhang, Fenghua Li, Daoyun Shi, Lijuan Gu, Yijia Xu, Yun
Published in
International Journal of Clinical and Experimental Pathology
Objective: As a chronic inflammatory skin disease of unknown etiology, vulvar leukoplakia mainly affects postmenopausal and peri-menopausal females. The main clinical manifestations of vulvar lichen sclerosus et atrophicus (VLSA) include itching, burning pain, and sexual dysfunction, which can lead to a decline in the quality of life. The existing ...
Wang, Xiuli Zhao, Yuhua Zou, Xiuli Wang, Li
Published in
International Journal of Clinical and Experimental Pathology
This study aimed to investigate the association of P16 and Ki67 expression in cervical conization with postoperative HPV reinfection and cervical intraepithelial neoplasia. This study retrospectively enrolled patients from January 2012 to December 2013. Patients with negative margins were followed up for 2 years to evaluate the correlation between ...
Du, Yang Jiang, Shukun Cheng, Longlong Liu, Jihui
Published in
International Journal of Clinical and Experimental Pathology
Psoriasis is reportedly modulated by the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) or vascular endothelial growth factor/p21-activated kinase 1 (VEGF/PAK1) pathways. However, no research has evaluated the expression of JAK/STAT and VEGF/PAK1 signaling pathway molecules in human psoriasis skin tissue concurrently. We...