Fu, Zhijie Gu, Lintao Li, Na Ma, Zhiyong Ling, Mingying Wang, Yuanyuan
Published in
International Journal of Clinical and Experimental Pathology
The pathophysiology of nasal polyps (NP) remains unclear, however, several ion channels may participate. Whether transient receptor potential canonical (TRPC) channel play a role in NP remains unknown. We investigated expression of TRPC, eosinophil infiltration, IL-6, and NF-κB in 58 patients with NP and 35 control subjects using hematoxylin-eosin ...
Zheng, Hongyu Li, Xingguo Chen, Yuan Zhou, Rudan Zhao, Hongbin Qian, Chuanyun
Published in
International Journal of Clinical and Experimental Pathology
Human umbilical cord-derived mesenchymal stem cells (hUCMSCs) are multipotent cells that have self-renewal properties and can differentiate into osteocytes, adipocytes, cartilage and extoderm. Bone regeneration and repair are important for the repair of bone injury, skeletal development or continuous remodeling throughout adult life. Thus, investig...
Kim, Hye Min Kim, Eun-Sol Koo, Ja Seung
Published in
International Journal of Clinical and Experimental Pathology
The aim of the study was to investigate the expression of serine/glycine-related proteins in Hürthle cell neoplasm (HCN) and follicular neoplasm (FN) and to explore its associated implications. Tissue microarrays were constructed with 265 cases of FN (follicular carcinoma [FC]: 112 and follicular adenoma [FA]: 153) and 107 cases of HCN (Hürthle cel...
Wang, Xiuli Li, Jing Liu, Duanyang Zhang, Lei Zhao, Baoshan Tang, Jing Yan, Meisi Kong, Dan Jin, Xiaoming
Published in
International Journal of Clinical and Experimental Pathology
Malignant ascites changes the microenvironment of the peritoneal cavity and damages abdominal functional host cells such as interstitial cells of Cajal (ICC), causing gastrointestinal dysfunction and poor prognosis. Besides tumor cells, malignant ascites contains large numbers of lymphocytes and macrophagocytes. These inflammatory cells act as a ‘d...
Zhao, Zhi Xu, Wei Xie, Jingming Wang, Yingsong Li, Tao Zhang, Ying Zhao, Daohong Bi, Ni Shi, Zhiyue
Published in
International Journal of Clinical and Experimental Pathology
The mechanisms and causes of scoliosis are believed to be multifactorial. Syringomyelia can often be found in scoliosis patients but the relationship between the two remains obscure. In this study, based on a rabbit model of syringomyelia-associated scoliosis, the involved pathological mechanism was explored in an attempt to further understand the ...
Li, Zan Li, Gang Jiang, Xin Fu, Xiaoming
Published in
International Journal of Clinical and Experimental Pathology
Cystic tumor of the atrioventricular node is an extremely rare primary tumor of the heart. Here we report a case of a 41-year-old female who presented with dizzy and palpitations. Electrocardiography revealed third-degree atrioventricular block. Echocardiography and Chest computed tomography showed a mass attached to the interatrial septum. Intraop...
Ren, Hongmiao Zhuang, Huiwen Xiong, Guanxia
Published in
International Journal of Clinical and Experimental Pathology
Extra-gonadal pure yolk sac tumor of the ear is very rare. We report a case of a yolk sac tumor of the ear and review the English literature in PubMed. The initial complaint was a mass protruding out of the external auditory canal. Computed tomography (CT) showed a large irregularly enhancing isodense mass lesion measuring 42*16 mm in the right ext...
Xiao, Yu-Juan Yang, Yao Liang, Yan-Hua
Published in
International Journal of Clinical and Experimental Pathology
Objectives: To investigate molecular mechanisms of nicastrin ( NCSTN ) mutations inducing acne inversa (AI). Methods: New and old lesional and non-lesional skin samples were obtained from an AI patient. Healthy skin samples were obtained from the buttocks of 100 non-AI patients. Hematoxylin-eosin staining and immunohistochemistry of NCSTN protein w...
Zhang, Ben-Jian Lan, Gui-Ping Si, Jin-Yuan Li, Yi-Liang Huang, Bo Deng, Zhuo-Xia Si, Yong-Feng Chen, Ming-Min Shen, Xiao-Ying Wang, Ying
...
Published in
International Journal of Clinical and Experimental Pathology
The aim of this study was to elaborate the correlation between metastasis-associated protein (MTA) family and the occurrence, progression, prognosis and chemotherapy efficiency in nasopharyngeal carcinoma (NPC).The expression of MTA1, MTA2 and MTA3 protein were detected by immunohistochemistry in a tissue microarray (TMAs) which contains tissue sam...
Shen, Jian-Dong Cai, Xin-Feng Wei, Jue Gu, Chun-Yan Ju, Lin-Ling Wang, Yi-Fang Dai, Feng Fu, Shou-Zhong Bian, Zhao-Lian Qi, Long-Ju
...
Published in
International Journal of Clinical and Experimental Pathology
Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. Tumor recurrence and metastasis are major factors that contribute to the poor outcome of patients with HCC. However, it is difficult to predict the prognosis of hepatocellular carcinoma. Trafficking Protein Particle Complex 4 (Trappc4), is associated with tumorigenesis...
