Liu, Duanrui Li, Binbin Yan, Bing Liu, Liang Jia, Yanfei Wang, Yunshan Ma, Xiaoli Yang, Fei
Published in
International Journal of Clinical and Experimental Pathology
Alpha-fetoprotein (AFP)-producing gastric cancer (AFPGC) is a relatively rare type of gastric cancer (GC). To improve the early diagnosis and treatment of AFPGC, we thoroughly investigated the clinicopathological features and prognosis of AFPGC. 139 GC patients who had received treatment from January 2013 to March 2016 in Jinan Central Hospital wer...
Zhan, Yudong Jiao, Zhaoshuang Niu, Li
Published in
International Journal of Clinical and Experimental Pathology
Purpose: To understand and explore the clinical manifestations, pathologic features, immunohistochemical analysis, treatment, and prognosis of dermatopathic lymphadenitis (DPL) and review the literature. Methods: Lymph node specimens were collected from 10 patients with DPL at Zhongnan Hospital of Wuhan University from 2016 to 2019. We identified 3...
Sun, Min Su, Shitong Liu, Queping Li, Qingling Wang, Kuansong
Published in
International Journal of Clinical and Experimental Pathology
Mucin-producing carcinomas are unusual primary malignancies of breast, and constitute about 1-4 percent of total breast cancer. The mammary mucin producing carcinomas are divided into 4 histologic subtypes according to WHO classification, including mucinous carcinoma, mucinous cystadenocarcinoma (MCA), columnar cell mucinous carcinoma (CCMC), and s...
Wang, Yuanyuan Xu, Ying Li, Ruiling Yuan, Ye
Published in
International Journal of Clinical and Experimental Pathology
Solitary fibrous tumors of the pleura (SFTPs) are rare slowly-growing tumors that originate from mesenchymal cells of the submesothelial tissue of the pleura. A 57-year-old female presented to our institute, and complained of mild chest discomfort for one year. The computed tomography (CT) showed a thoracic mass measuring 3.4×1.5 cm. She refused su...
Ma, Li’an Yan, Jifu Shen, Junquan Sang, Jianzhong Xu, Huanjun
Published in
International Journal of Clinical and Experimental Pathology
Objective: To discuss the feasibility of water infusion colonoscopy and its difference with traditional air insufflation colonoscopy in application value. Methods: A prospective randomized controlled clinical study was designed to include 200 patients who underwent sedation-free diagnostic colonoscopy. Among them, 100 patients were treated with wat...
Yu, Wenjuan Zhao, Bei Zhong, Haizhen Yao, Gang
Published in
International Journal of Clinical and Experimental Pathology
Objective: Epidemiologic studies have shown that, compared to men, women have better prognoses in chronic renal diseases. This indicates that gender hormones may have some effect on renal function. The present study aimed to investigate the expression and relationship with prognosis of estrogen receptor alpha (ERα) in renal tissue of immunoglobulin...
Li, Jia Rong, Xiaoling Liu, Yuwu Du, Jing
Published in
International Journal of Clinical and Experimental Pathology
Cervical squamous cancer is a common malignancy of the female reproductive system, and the age of onset is getting younger. PI3K and ERK, are key components in maintaining the development of malignant tumor, but have not been studied in cervical squamous cancer. Objective: To explore the differences in disease susceptibility to human papilloma viru...
Huang, Xiao Cai, Wei Liu, Li Yuan, Wenliang
Published in
International Journal of Clinical and Experimental Pathology
Background: Tumor immunotherapy has become an important means of cancer treatment. A response depends on the interaction of tumor cells with immune regulators in the tumor microenvironment, which plays an important role in inhibiting or enhancing the immune response. However, lymph node (LN) metastasis leads to major changes in the tumor microenvir...
Tang, Shihang Zhao, Chong Chen, Weiqing
Published in
International Journal of Clinical and Experimental Pathology
Hemophagocytic lymphohistiocytosis (HLH) is a rare fatal hyperinflammatory syndrome resulting in cytokine storm and secondary multi-organ impairment. The natural killer (NK)/T-cell lymphoma is the predominant subtype in patients with lymphoma-associated hemophagocytic syndrome (LAHS) in Asia. Yet the non-Hodgkin’s B-cell lymphoma is a relatively un...
Zhou, Huihui Xie, Chao Li, Weilong Zhan, Jinping Chen, Weiyi Yang, Ping Zhang, Yuanfeng Yu, Shengqiang Lin, Haiyan
Published in
International Journal of Clinical and Experimental Pathology
Epstein-Barr virus-positive follicular lymphoma (EBV-positive FL) is extremely uncommon, especially a histiocytoid morphology. Here we present a 70-year-old man who had EBV-positive FL with diffuse large B-cell lymphoma (DLBCL) transformation in the left cervical lymph nodes.
