Tay, Carina Jing Xuan Ta, Le Duc Huy Ow Yeong, Yu Xiang Yap, Gaik Chin Chu, Justin Jang Hann Lee, Bee Wah Tham, Elizabeth Huiwen
Published in
International Archives of Allergy and Immunology
There is emerging evidence that the respiratory microbiota influences airway health, and there has been intense research interest in its role in respiratory infections and allergic airway disorders. This review aims to summarize current knowledge of nasal microbiome and virome and their associations with childhood rhinitis and wheeze. The healthy i...
Bousquet, Jean Czarlewski, Wienczyslawa Zuberbier, Torsten Mullol, Joaquim Blain, Hubert Cristol, Jean-Paul De La Torre, Rafael Pizarro Lozano, Nieves Le Moing, Vincent Bedbrook, Anna
...
Published in
International Archives of Allergy and Immunology
In this article, we propose that differences in COVID-19 morbidity may be associated with transient receptor potential ankyrin 1 (TRPA1) and/or transient receptor potential vanilloid 1 (TRPV1) activation as well as desensitization. TRPA1 and TRPV1 induce inflammation and play a key role in the physiology of almost all organs. They may augment senso...
Strizova, Zuzana Smetanova, Jitka Bartunkova, Jirina Milota, Tomas
Published in
International Archives of Allergy and Immunology
The number of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients keeps rising in most of the European countries despite the pandemic precaution measures. The current antiviral and anti-inflammatory therapeutic approaches are only supportive, have limited efficacy, and the prevention in reducing the transmission of SARS-C...
Rezaei, Mitra Marjani, Majid Mahmoudi, Shima Mortaz, Esmaeil Mansouri, Davood
Published in
International Archives of Allergy and Immunology
Background: Although the pathophysiology of coronavirus disease 2019 (COVID-19) is not clearly defined, among the proposed mechanisms, immune system dysfunction is more likely than others. The aim of this study was to clarify the characteristics and clinical significance of dynamic changes of lymphocyte subsets in the course of COVID-19. Methods: I...
Gupta, Sudhir Su, Houfen Narsai, Tejal Agrawal, Sudhanshu
Published in
International Archives of Allergy and Immunology
We report perhaps the most comprehensive study of subsets of CD4+ and CD8+ and subsets of B cells in a mild symptomatic SARS-CoV-2+ immunocompetent patient and a common variable immunodeficiency disease (CVID) patient who had normal absolute lymphocyte counts and remained negative for SARS-CoV-2 IgG antibodies. Naïve (TN), central memory (TCM), eff...
Zhan, Jia-Bin Zheng, Jing Zeng, Lian-Ya Fu, Zhi Huang, Qiu-Ju Wei, Xin Zeng, Min
Published in
International Archives of Allergy and Immunology
Background: This study aims to investigate the regulatory effect of microRNA-96-5p (miR-96-5p) in the pathophysiological process of allergic rhinitis (AR). Methods: Nasal mucosal tissue samples were collected from AR patients and healthy controls. An in vitro AR model was established by stimulating human nasal epithelial cells (HNECs) with interleu...
Yang, Shuai Chew, Huifang Jiang, Yuchi Cheng, Lei Guo, Xiaoya Che, Huilian Sun, Na
Published in
International Archives of Allergy and Immunology
Introduction: Biological rhythm is inextricably linked to the physiological mechanisms of allergic diseases, but the exact mechanisms are still poorly understood. Clinical studies have reported rhythmic fluctuations in allergic diseases. The search for natural and harmless active ingredients based on biological rhythm with which to regulate allergi...
Bousquet, Jean Czarlewski, Wienczyslawa Zuberbier, Torsten Mullol, Joaquim Blain, Hubert Cristol, Jean-Paul De La Torre, Rafael Le Moing, Vincent Pizarro Lozano, Nieves Bedbrook, Anna
...
Published in
International Archives of Allergy and Immunology
There are large country variations in COVID-19 death rates that may be partly explained by diet. Many countries with low COVID-19 death rates have a common feature of eating large quantities of fermented vegetables such as cabbage and, in some continents, various spices. Fermented vegetables and spices are agonists of the antioxidant transcription ...
Irani, Carla Haczku, Angela
Published in
International Archives of Allergy and Immunology
Wang, Suqin Dong, Jiazhi Huang, Lingling
Published in
International Archives of Allergy and Immunology
Background: Cytokine polymorphismsmight influence the predisposition to diabetic nephropathy (DN), but the results of already published related studies are still controversial and ambiguous. Objectives: The authors designed this meta-analysis to more precisely estimate relationships between TNF-α/IL-1/IL-4/IL-8/IL-18polymorphisms and DN by pooling ...
