Nguyen, Aileen Mahaffy, Joseph Vaidya, Naveen K
Published in
Infectious Disease Modelling
Lyme disease is the most prevalent tick-borne disease in the United States, which humans acquire from an infected tick of the genus Ixodes (primarily Ixodes scapularis). While previous studies have provided useful insights into various aspects of Lyme disease, the tick's host preference in the presence of multiple hosts has not been considered in t...
Dénes, Attila Gumel, Abba B.
Published in
Infectious Disease Modelling
The quarantine of people suspected of being exposed to an infectious agent is one of the most basic public health measure that has historically been used to combat the spread of communicable diseases in human communities. This study presents a new deterministic model for assessing the population-level impact of the quarantine of individuals suspect...
Saldaña, Fernando Barradas, Ignacio
Published in
Infectious Disease Modelling
In this paper, we study general recovery functions and treatment in the dynamics of an S I S model for sexually transmitted infections with nonzero partnership length. It is shown how partnership dynamics influences the predicted prevalence at the steady state and the basic reproduction number. Sobol's indices are used to evaluate the contribution ...
Titus Muurlink, Olav Stephenson, Peter Islam, Mohammad Zahirul Taylor-Robinson, Andrew W.
Published in
Infectious Disease Modelling
The effects of weather variables on the transmission of vector-borne diseases are complex. Relationships can be non-linear, specific to particular geographic locations, and involve long lag times between predictors and outbreaks of disease. This study expands the geographical and temporal range of previous studies in Bangladesh of the mosquito-tran...
Olawoyin, Omomayowa Kribs, Christopher
Published in
Infectious Disease Modelling
Although the Zika virus is transmitted to humans primarily through the bite of infected female Aedes aegypti mosquitoes, it can also be sexually and vertically transmitted within both populations. In this study, we develop a new mathematical model of the Zika virus which incorporates sexual transmission in humans and mosquitos, vertical transmissio...
Azevedo, Franciane Amaku, Marcos Coutinho, Francisco Antonio Bezerra Lopez, Luis Fernandez Massad, Eduardo
Published in
Infectious Disease Modelling
We consider nested or multiscale models to study the effect of the temporal evolution of the disease within the host in the population dynamics of the disease, for one and two infectious agents. We assumed a coupling between the within-host infection rate and the between-host transmission rate. The age of infection within each individual in a popul...
Yu, Yi Shi, Yi Yao, Wei
Published in
Infectious Disease Modelling
Infectious diseases have always been a problem that threatens people's health and tuberculosis is one of the major. With the development of medical scientific research, drug-resistant infectious diseases have become a more intractable threat because various drugs and antibiotics are widely used in the process of fighting against infectious diseases...
Ayoub, Houssein H. Awad, Susanne F. Abu-Raddad, Laith J.
Published in
Infectious Disease Modelling
Introduction HIV epidemics in hard-to-reach high-risk subpopulations are often discovered years after epidemic emergence in settings with poor surveillance infrastructure. Using hypothesis-generation modeling, we aimed to investigate and demonstrate the concept of using routine HIV testing data to identify and characterize hidden epidemics in high-...
Mohammed-Awel, Jemal Agusto, Folashade Mickens, Ronald E. Gumel, Abba B.
Published in
Infectious Disease Modelling
The large-scale use of insecticide-treated bednets (ITNs) and indoor residual spraying (IRS), over the last two decades, has resulted in a dramatic reduction of malaria incidence globally. However, the effectiveness of these interventions is now being threatened by numerous factors, such as resistance to insecticide in the mosquito vector and their...
Lou, Jie Cheng, Jinjin Li, Yan Zhang, Chen Xing, Hui Ruan, Yuhua Shao, Yiming
Published in
Infectious Disease Modelling
As proposed in the UNAIDSs 2014 report, to end global AIDS epidemic by 2030, 90% of people living with HIV need to be diagnosed, 90% of the diagnosed need to receive antiretroviral therapy (ART), and 90% of those on treatment need to achieve viral suppression (90-90-90 strategy). The strategies focus on the reservoir. It controls HIV spreading by r...