Mohan, Vandana Ashwani, Koul
Published in
Indian Journal of Pharmacology
BACKGROUND: The present study aims to unravel the pro-apoptotic, anti-metastatic, and anti-telomerase activity of aqueous extract of Tinospora cordifolia stem (Aq.Tc) and its active component arabinogalactan (AG) during Benzo(a)pyrene [B(a)P]-induced lung tumorigenesis in mice. MATERIALS AND METHODS: Lung tumors were induced in male BALB/c mice usi...
Saifuddin, P. K. Tandon, Moksh Kalaiselvan, Vivekanandan Suroy, Benjamin Pattanshetti, Vidya Prakash, Ajay Medhi, Bikash
Published in
Indian Journal of Pharmacology
Postmarketing vigilance system for medical devices in India is not as vigorous as of drugs. W Materiovigilance involves post marketing surveillance of adverse events caused by medical devices. As per directive of WHO, many countries including India have established their own post marketing surveillance system. In India it is known as Materiovigilan...
Mishra, S. R. P. K. Samal, Rajashree Behera, B.
Published in
Indian Journal of Pharmacology
OBJECTIVE: The objective of the study was to assess the efficacy and safety profiles of combined treatment of prednisolone with thalidomide (Gr-A) and prednisolone with clofazimine (Gr. B) in patients with erythema nodosum leprosum (ENL) or type 2 lepra reactions. MATERIALS AND METHODS: Efficacy of both regimens was assessed on the basis of clinica...
Zaiem, Ahmed Hammamia, Syrine Ben Aouinti, Imen Charfi, Ons Ladhari, Walid Kastalli, Sarrah Aidli, Sihem El Lakhoua, Ghozlane
Published in
Indian Journal of Pharmacology
INTRODUCTION: Chemotherapy drugs can be responsible of several side effects such as hand–foot syndrome (HFS). This syndrome is also called “palmar-plantar erythrodysesthesia” and “acral erythema.” Without proper management, it can deteriorate the quality of life of a patient, leading to temporary or definitive stop of chemotherapy. AIM OF THIS STUD...
Nalini, R. Ramya, J. Ezhil Karthick, R.
Published in
Indian Journal of Pharmacology
INTRODUCTION: Statins are effective in reducing low-density lipoprotein cholesterol and are favorable in primary and secondary prevention of cardiovascular disease. Recent large trials have linked the use of statins and increased incidence of new-onset diabetes mellitus, the possibility of worsening of glucose level in individuals with diabetes fol...
Singh, Surjit Khasbage, Sameer Kaur, Rimple Jeet Sidhu, Jaspreet Kaur Bhandari, Bharti
Published in
Indian Journal of Pharmacology
During present decade, targeted drug therapy has been the epitome for treatment of cancer. Drugs like Imatinib, a tyrosine kinase receptor inhibitor and Trastuzumab, an human epidermal growth factor receptor-2/neu inhibitor, has been developed and accepted widely for management of chronic myeloid leukaemia and breast cancer respectively. Recent dev...
Das, Ayan Kumar Dudeja, Mridu Kohli, Sunil Ray, Pratima Nandy, Shyamasree
Published in
Indian Journal of Pharmacology
CONTEXT: Enterococci are known to cause life-threatening infections which are difficult to treat as the organism harbors innate resistance to many antibiotics and can amass resistance toward many others through plasmid-mediated genetic exchange. AIMS: The study evaluates the drug susceptibility profile of various Enterococcus species isolated from ...
Choudhary, Gajendra Prabha, Praisy K Gupta, Shreya Prakash, Ajay Medhi, Bikash
Published in
Indian journal of pharmacology
Deepak, H. B. Prince, Sabina Evan Deshpande, Pratima
Published in
Indian Journal of Pharmacology
OBJECTIVES: Psoriasis is a chronic infectious skin disease triggered by an autoimmune process involving T-cell-mediated hyper-proliferation of keratinocytes. The objective of this study is to assess the modulation of programmed death 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) through JAK/STAT pathway during the development of a ...
Thangaraju, Pugazhenthan Mahesh, Kothapalli Venkatesan, Sajitha
Published in
Indian Journal of Pharmacology
Drug information can be obtained from various drug information sources that were available as government (National Formulary of India [NFI]; Central Drugs Standard Control Organization [CDSCO]), as well as commercial documents (Current Index of Medical Specialties [CIMS] and Monthly Index of Medical Specialties [MIMS]). Irrational drug usage may ha...
