Tepekoy, Filiz Uysal, Fatma Acar, Nuray Ustunel, Ismail Akkoyunlu, Gokhan
Published in
Histochemistry and cell biology
Wide application of gonadotropin-releasing hormone (GnRH) agonists and antagonists for clinical purposes determines their effects on ovarian signaling pathways. Our study aimed to determine the localization, expression levels of Wnt signaling members in the pubertal and adult mouse ovary and the impact of GnRH antagonist cetrorelix on these signali...
Ravishankar, Hemanth Mangani, Abubakar Siddiq Shankar, M Bhavani Joshi, Mayur Devasena, T Parameswaran, Sowmya Subramaniam, Krishnakumar
Published in
Histochemistry and cell biology
Retinoblastoma (RB) is a childhood eye tumor, caused by the RB1 gene mutation. Since RB is a rapidly proliferating tumor, the patient presents with a Group-D/E tumor at the time of diagnosis. Enucleation is preferred in most unilateral cases to prevent metastasis. Various cell lines have been established to study the tumor's growth pattern and targ...
Park, Sujin Zuber, Christian Roth, Jürgen
Published in
Histochemistry and cell biology
Autophagy is a degradative cellular process that can be both non-selective and selective and begins with the formation of a unique smooth double-membrane phagophore which wraps around a portion of the cytoplasm. Excess and damaged organelles and cytoplasmic protein aggregates are degraded by selective autophagy. Previously, we reported that in fed ...
Bloomer, Steven A Moyer, Eric D Brown, Kyle E Kregel, Kevin C
Published in
Histochemistry and cell biology
Macrophages have vital roles in innate immunity by modulating the inflammatory response via their ability to alter their phenotype from pro-inflammatory (M1) to anti-inflammatory (M2). Aging increases activation of the innate immune system, and macrophage numbers increase in the aged liver. Since macrophages also produce free radical molecules, the...
Kurokawa, Yuna Masatani, Tatsunori Konishi, Rikako Tomioku, Kanna Xuan, Xuenan Fujita, Akikazu
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Histochemistry and cell biology
Glycosylphosphatidylinositol (GPI)-anchored proteins typically localise to lipid rafts. GPI-anchored protein microdomains may be present in the plasma membrane; however, they have been studied using heterogeneously expressed GPI-anchored proteins, and the two-dimensional distributions of endogenous molecules in the plasma membrane are difficult to ...
Leopold, Barbara Strutz, Jasmin Weiß, Elisa Gindlhuber, Juergen Birner-Gruenberger, Ruth Hackl, Hubert Appel, Hannah M Cvitic, Silvija Hiden, Ursula
Published in
Histochemistry and cell biology
Function and dysfunction of endothelial cells are regulated by a multitude of factors. Endothelial cell research often requires in vitro cell culture experiments. Hence, various culture media specifically designed to promote endothelial cell growth are available. These strikingly differ in their composition: complex media contain endothelial cell g...
Ichii, Osamu Nakamura, Teppei Irie, Takao Otani, Yuki Hosotani, Marina Masum, Md Abdul Islam, Rashedul Md Horino, Taro Sunden, Yuji Elewa, Yaser Hosny Ali
...
Published in
Histochemistry and cell biology
The increased prevalence of aging-related chronic kidney disease (CKD) among humans is a problem worldwide. Aged cotton rats (Sigmodon hispidus) are considered novel model animals for studying CKD, especially as the females develop severe tubulointerstitial lesions with anemia. To investigate the renal pathologic features in aged male cotton rats a...
Taatjes, Douglas J Roth, Jürgen
Published in
Histochemistry and cell biology
Pitts, Mallory S McShane, Josh N Hoener, Marius C Christian, Sherri L Berry, Mark D
Published in
Histochemistry and cell biology
Trace amine-associated receptors are G protein-coupled receptors of which TAAR1 is the most well-studied. Recently, Vattai et al. (J Cancer Res Clin Oncol 143:1637-1647 https://doi.org/10.1007/s00432-017-2420-8 , 2017) reported that expression of TAAR1 may be a marker of breast cancer (BC) survival, with a positive correlation also suggested betwee...
Taatjes, Douglas J Roth, Jürgen
Published in
Histochemistry and cell biology
