Lee, Andrea K Y Andrade, Jason Hawkins, Nathaniel M Alexander, George Bennett, Matthew T Chakrabarti, Shanta Laksman, Zachary W Krahn, Andrew Yeung-Lai-Wah, John A Deyell, Marc William
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Published in
Heart (British Cardiac Society)
The natural history of frequent premature ventricular complexes (PVCs) in association with preserved left ventricular ejection fraction (LVEF) is uncertain. The optimal management of this population is thus undefined. We studied the outcomes of untreated patients with frequent PVCs and preserved LVEF. This cohort study prospectively evaluated conse...
Dobson, Rebecca Joshi, Abhishek Allen, Christopher Sinclair, Hannah C
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Heart (British Cardiac Society)
Jawad, Mohammed Vamos, Eszter P Najim, Muhammad Roberts, Bayard Millett, Christopher
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Heart (British Cardiac Society)
Prolonged armed conflict may constrain efforts to address non-communicable disease in some settings. We assessed the impact of armed conflict on cardiovascular disease (CVD) risk among civilians in low/middle-income countries (LMICs). In February 2019, we performed a systematic review searching Medline, Embase, PsychINFO, Global Health and Web of S...
Schichtel, Markus Wee, Bee Perera, Rafael Onakpoya, Igho Albury, Charlotte Barber, Sarah
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Heart (British Cardiac Society)
Advance care planning (ACP) is widely advocated to contribute to better outcomes for patients suffering from heart failure. But clinicians appear hesitant to engage with ACP. Our aim was to identify interventions with the greatest potential to engage clinicians with ACP in heart failure. A systematic review and meta-analysis. We searched CINAHL, Co...
Beggs, Simon A S Rørth, Rasmus Gardner, Roy S McMurray, John J V
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Heart (British Cardiac Society)
Heart failure is a prothrombotic state, and it has been hypothesised that thrombosis and embolism cause non-fatal and fatal events in heart failure and reduced ejection fraction (HFrEF). We sought to determine the effect of anticoagulant therapy on clinical outcomes in patients with HFrEF who are in sinus rhythm. We conducted an updated systematic ...
Kapłon-Cieślicka, Agnieszka Budnik, Monika Gawałko, Monika Peller, Michał Gorczyca, Iwona Michalska, Anna Babiarz, Aldona Bodys, Aleksandra Uliński, Robert Żochowski, Maciej
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Heart (British Cardiac Society)
We aimed to identify predictors of left atrial appendage (LAA) thrombus in patients with atrial fibrillation (AF) and to enhance the prognostic value of the CHA2DS2-VASc score. Derivation cohort included 1033 consecutive AF patients referred for catheter ablation or direct current cardioversion, in whom transoesophageal echocardiography (TOE) was p...
Yu, Xinyu Jiang, Dingsheng Wang, Jing Wang, Rui Chen, Taiqiang Wang, Kan Durgahee, Mouniir Sha Ahmad Wei, Xiang Cao, Shiyi
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Heart (British Cardiac Society)
To assess the association of metformin prescription with the risk of aortic aneurysm, aortic aneurysm events and the enlargement of abdominal aortic aneurysm (AAA). Systematic review and meta-analysis. We searched PubMed, Embase and Scopus for epidemiological studies up to November 2018. We included observational studies which evaluated the associa...
Tajik, Behnam Tuomainen, Tomi-Pekka Kurl, Sudhir Salonen, Jukka Virtanen, Jyrki K
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Heart (British Cardiac Society)
Long-chain omega-3 polyunsaturated fatty acids (PUFA) from fish have been inversely associated with coronary heart disease (CHD) risk. Fish may also contain methylmercury, which has been associated with higher CHD risk and may diminish the cardioprotective effect of long-chain omega-3 PUFA. We investigated the associations of serum long-chain omega...
Park, Sung Keun Jung, Ju Young Kang, Jeong Gyu Chung, Pil-Wook Oh, Chang-Mo
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Heart (British Cardiac Society)
Left ventricular (LV) geometry change is an independent predictor for cardiovascular disease. However, data are equivocal on the association of echocardiographic parameters of LV geometry with incident hypertension. Thus, we were to investigate the risk of hypertension according to the baseline echocardiographic parameters of LV geometry. Study par...
Radhakrishnan, Ashwin Pickup, Luke C Price, Anna M Law, Jonathan P Edwards, Nicola C Steeds, Richard P Ferro, Charles J Townend, Jonathan N
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Heart (British Cardiac Society)
The syndrome of uraemic cardiomyopathy, characterised by left ventricular hypertrophy, diffuse fibrosis and systolic and diastolic dysfunction, is common in chronic kidney disease and is associated with an increased risk of cardiovascular morbidity and mortality. The pathophysiological mechanisms leading to uraemic cardiomyopathy are not fully unde...
