Gonzalez-Quereda, Lidia Rodriguez, Maria Jose Diaz-Manera, Jordi Alonso-Perez, Jorge Gallardo, Eduard Nascimento, Andres Ortez, Carlos Natera-de Benito, Daniel Olive, Montse Gonzalez-Mera, Laura
...
Published in
Genes
The term neuromuscular disorder (NMD) includes many genetic and acquired diseases and differential diagnosis can be challenging. Next-generation sequencing (NGS) is especially useful in this setting given the large number of possible candidate genes, the clinical, pathological, and genetic heterogeneity, the absence of an established genotype-pheno...
Suwala, Grzegorz Altmanová, Marie Mazzoleni, Sofia Karameta, Emmanouela Pafilis, Panayiotis Kratochvíl, Lukáš Rovatsos, Michail
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Genes
Lacertid lizards are a widely radiated group of squamate reptiles with long-term stable ZZ/ZW sex chromosomes. Despite their family-wide homology of Z-specific gene content, previous cytogenetic studies revealed significant variability in the size, morphology, and heterochromatin distribution of their W chromosome. However, there is little evidence...
Lanznaster, Débora Veyrat-Durebex, Charlotte Vourc’h, Patrick Andres, Christian R. Blasco, Hélène Corcia, Philippe
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Genes
Metabolomics studies performed in patients with amyotrophic lateral sclerosis (ALS) reveal a set of distinct metabolites that can shed light on the pathological alterations taking place in each individual. Metabolites levels are influenced by disease status, and genetics play an important role both in familial and sporadic ALS cases. Metabolomics a...
Thabet, Samar G. Moursi, Yasser S. Karam, Mohamed A. Börner, Andreas Alqudah, Ahmad M.
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Genes
Drought stress can occur at any growth stage and can affect crop productivity, which can result in large yield losses all over the world. In this respect, understanding the genetic architecture of agronomic traits under drought stress is essential for increasing crop yield potential and harvest. Barley is considered the most abiotic stress-tolerant...
Wenne, Roman Zbawicka, Małgorzata Bach, Lis Strelkov, Petr Gantsevich, Mikhail Kukliński, Piotr Kijewski, Tomasz McDonald, John H. Sundsaasen, Kristil Kindem Árnyasi, Mariann
...
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Genes
Large-scale climate changes influence the geographic distribution of biodiversity. Many taxa have been reported to extend or reduce their geographic range, move poleward or displace other species. However, for closely related species that can hybridize in the natural environment, displacement is not the only effect of changes of environmental varia...
Burns, Madeline P. Cavallaro, Frederick D. Saltz, Julia B.
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Genes
Decision making is involved in many behaviors contributing to fitness, such as habitat choice, mate selection, and foraging. Because of this, high decision-making accuracy (i.e., selecting the option most beneficial for fitness) should be under strong selection. However, decision making is energetically costly, often involving substantial time and ...
Sultana, Nusrat Menzel, Gerhard Heitkam, Tony Kojima, Kenji K. Bao, Weidong Serçe, Sedat
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Genes
Bioinformatic and molecular characterization of satellite repeats was performed to understand the impact of their diversification on Vaccinium genome evolution. Satellite repeat diversity was evaluated in four cultivated and wild species, including the diploid species Vaccinium myrtillus and Vaccinium uliginosum , as well as the tetraploid species ...
Mahmoudi, Omid Wahab, Abdul Chong, Kil To
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Genes
One of the most common and well studied post-transcription modifications in RNAs is N6-methyladenosine (m6A) which has been involved with a wide range of biological processes. Over the past decades, N6-methyladenosine produced some positive consequences through the high-throughput laboratory techniques but still, these lab processes are time consum...
Paduano, Francesco Colao, Emma Loddo, Sara Orlando, Valeria Trapasso, Francesco Novelli, Antonio Perrotti, Nicola Iuliano, Rodolfo
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Genes
Copy number variations (CNVs) play a key role in the pathogenesis of several diseases, including a wide range of neurodevelopmental disorders. Here, we describe the detection of three CNVs simultaneously in a female patient with evidence of severe myoclonic epilepsy, microcephaly, hypertelorism, dimorphisms as well as severe psychomotor delay and i...
Mendoza, Mayra N. Raudsepp, Terje More, Manuel J. Gutiérrez, Gustavo A. Ponce de León, F. Abel
Published in
Genes
Alpaca is a camelid species of broad economic, biological and biomedical interest, and an essential part of the cultural and historical heritage of Peru. Recently, efforts have been made to improve knowledge of the alpaca genome, and its genetics and cytogenetics, to develop molecular tools for selection and breeding. Here, we report cytogenetic ma...
