Belay, Demeke Mesfin Worku, Workie Zemene Wondim, Amare Hailemeskel, Habtamu Shimels Bayih, Wubet Alebachew
Published in
Frontiers in Pediatrics
Background Pre-maturity is the primary cause of neonatal mortality in the world. Although prematurity was the leading cause of neonatal mortality, the survival rate and its predictors may be varied from setting to setting and time to time due to different reasons. Therefore, this study aimed to assess the survival probability and predictors of mort...
Liu, Shu Wang, Zhiqing Zheng, Xianhua Zhang, Ye Wei, Sisi OuYang, Haimei Liang, Jinqun Chen, Nuan Zeng, Weihong Jiang, Jianhui
...
Published in
Frontiers in Pediatrics
Background Severe hyperlipidemia is characterized by markedly elevated blood triglyceride levels and severe early-onset cardiovascular diseases, pancreatitis, pancreatic necrosis or persistent multiple organ failure if left untreated. It is a rare autosomal recessive metabolic disorder originated from the variants of lipoprotein lipase gene, and pr...
Tolunay, Orkun Çelik, Ümit Arslan, Ilknur Tutun, Bugra Özkaya, Merve
Published in
Frontiers in Pediatrics
Objective The objective of the study is to evaluate the clinical findings and treatment results of COVID-19 in pediatric cancer patients. Study design The study was designed as a single-center retrospective observational study. Pediatric cancer patients with COVID-19 admitted to the University of Health Sciences Adana City Training and Research Hos...
van der Velden, Fabian J. S. Gennery, Andrew R. Emonts, Marieke
Published in
Frontiers in Pediatrics
Objective This study aims to assess the performance of biomarkers used for the prediction of bacterial, viral, and fungal infection in immunocompromised children upon presentation with fever. Methods We performed a literature search using PubMed and MEDLINE and In-Process & Other Non-indexed Citations databases. Cohort and case–control studies asse...
Sundquist, Fredrik Georgantzi, Kleopatra Jarvis, Kirsten Brunsvig Brok, Jesper Koskenvuo, Minna Rascon, Jelena van Noesel, Max Grybäck, Per Nilsson, Joachim Braat, Arthur
...
Published in
Frontiers in Pediatrics
Background Half the children with high-risk neuroblastoma die with widespread metastases. Molecular radiotherapy is an attractive systemic treatment for this relatively radiosensitive tumor. 131I-mIBG is the most widely used form in current use, but is not universally effective. Clinical trials of 177Lutetium DOTATATE have so far had disappointing ...
Morales Junior, Ronaldo Pereira, Gabriela Otofuji Tiguman, Gustavo Magno Baldin Juodinis, Vanessa D'Amaro Telles, João Paulo de Souza, Daniela Carla Santos, Silvia Regina Cavani Jorge
Published in
Frontiers in Pediatrics
The antimicrobial therapy of sepsis and septic shock should be individualized based on pharmacokinetic/pharmacodynamic (PK/PD) parameters to deliver effective and timely treatment of life-threatening infections. We conducted a literature scoping review to identify therapeutic targets of beta-lactam antibiotics in septic pediatric patients and the s...
Rodriguez, Vilmarie
Published in
Frontiers in Pediatrics
Pediatric acute lymphoblastic leukemia (ALL) has achieved close to 90% cure rates through extensive collaborative and integrative molecular research, clinical studies, and advances in supportive care. Despite this high achievement, venous thromboembolic complications (VTE) remain one of the most common and potentially preventable therapy-associated...
Liu, Zongzhi Wang, Xiaojiao Zhang, Zilong Yang, Zixin Wang, Junyun Wang, Yajuan
Published in
Frontiers in Pediatrics
Background Pseudohypoaldosteronism (PHA) diseases are difficult to diagnose because symptoms are often non-specific and an in-depth pathogenesis study is still lacking. Case Presentation We present the case of a 19-day-old neonate who presented with unexplained recurrent hyperkalaemia, hypovolemia and metabolic acidosis, whose parents did not have ...
Iskandar, Kristy Simanjaya, Susan Indrawan, Taufik Kalim, Alvin Santoso Marcellus, Heriyanto, Didik Setyo Gunadi,
Published in
Frontiers in Pediatrics
Background Hirschsprung disease (HSCR) is a heterogeneous genetic disease characterized by the absence of ganglion cells in the intestinal tract. The REarranged during Transfection (RET) is the most responsible gene for its pathogenesis. RET’s somatic mosaicisms have been reported for HSCR; however, they are still under-recognized. Therefore, we de...
Thaulow, Christian Magnus Berild, Dag Blix, Hege Salvesen Brigtsen, Anne Karin Myklebust, Tor Åge Eriksen, Beate Horsberg
Published in
Frontiers in Pediatrics
