Avalon, Nicole E. Murray, Alison E. Daligault, Hajnalka E. Lo, Chien-Chi Davenport, Karen W. Dichosa, Armand E. K. Chain, Patrick S. G. Baker, Bill J.
Published in
Frontiers in Chemistry
Complex interactions exist between microbiomes and their hosts. Increasingly, defensive metabolites that have been attributed to host biosynthetic capability are now being recognized as products of host-associated microbes. These unique metabolites often have bioactivity targets in human disease and can be purposed as pharmaceuticals. Polyketides a...
Petlitckaia, Svetlana Vincente, Jérôme Poulesquen, Arnaud
Published in
Frontiers in Chemistry
Metakaolin based geopolymer foams were synthesized at room temperature by direct foaming using hydrogen peroxide (H2O2) as a blowing agent and two types of surfactants such as AER5 and CTAB allowing to tune the connection between two adjacent cells. In the field of decontamination process of liquid wastes, the knowledge of the topology of the gener...
Hegde, Shalakha Tang, Zhichao Zhao, Junxing Wang, Jingxin
Published in
Frontiers in Chemistry
The ongoing COVID-19/Severe Acute Respiratory Syndrome CoV-2 (SARS-CoV-2) pandemic has become a significant threat to public health and has hugely impacted societies globally. Targeting conserved SARS-CoV-2 RNA structures and sequences essential for viral genome translation is a novel approach to inhibit viral infection and progression. This new ph...
Deng, Ming-Rong Li, Yan Luo, Xiao Zheng, Xiang-Ling Chen, Yuchan Zhang, Yu-Lian Zhang, Weimin Zhou, Hao Zhu, Honghui
Published in
Frontiers in Chemistry
Granaticins are benzoisochromanequinone polyketides with remarkable antibacterial and anticancer activities. Three sulfur-containing granaticin congeners, mycothiogranaticins A (1), B (2) and granaticin MA (3) were discovered from a granaticin-producing strain of Streptomyces vietnamensis GIMV4.0001. Two of them were structurally determined with my...
Yakubovich, Alexander Odinokov, Alexey Nikolenko, Sergey Jung, Yongsik Choi, Hyeonho
Published in
Frontiers in Chemistry
We present a computational workflow based on quantum chemical calculations and generative models based on deep neural networks for the discovery of novel materials. We apply the developed workflow to search for molecules suitable for the fusion of triplet-triplet excitations (triplet-triplet fusion, TTF) in blue OLED devices. By applying generative...
Luo, Zhao-Xiang Liu, Miao Li, Tian Xiong, De-Cai Ye, Xin-Shan
Published in
Frontiers in Chemistry
Herein, the convenient one-step electrochemical bromination of glycals using Bu4NBr as the brominating source under metal-catalyst-free and oxidant-free reaction conditions was described. A series of 2-bromoglycals bearing different electron-withdrawing or electron-donating protective groups were successfully synthesized in moderate to excellent yi...
Kaur, Vishaldeep Sharma, Mridu Sen, Tapasi
Published in
Frontiers in Chemistry
The abundance of hotspots tuned via precise arrangement of coupled plasmonic nanostructures highly boost the surface-enhanced Raman scattering (SERS) signal enhancements, expanding their potential applicability to a diverse range of applications. Herein, nanoscale assembly of Ag coated Au nanostars in dimer and trimer configurations with tunable na...
Yang, Yuqin Li, Feifei Yan, Mengmeng Chen, Shan Cai, Desheng Liu, Xiaojing Han, Nana Yuan, Zhihua Lu, Jihui Zhang, Yaozhi
...
Published in
Frontiers in Chemistry
Researchers often focus on the mechanisms of synergistic agents, a few explore drug combinations that enhance toxicity, while few have studied the internal mechanism of compatibility enhancement in chemical level. Herein, we present a comprehensive analysis based on ultra-high-performance liquid chromatography coupled with quadrupole-Orbitrap high-...
Xing, Liwen Jin, Yujuan Weng, Yunxuan Ji, Yongjun
Published in
Frontiers in Chemistry
Numerous efforts have been devoted to investigating the catalytic events and disclosing the catalytic nature of the metal-carbon interaction interface. Nevertheless, the local deconstruction of catalytically active metal-carbon interface was still missing. Herein, the selected four types of landmark catalytic paradigms were highlighted, which was e...
Zhu, Jianyu Dou, Leina Shao, Shibei Kou, Jiaqian Yu, Xuezhi Wen, Kai Wang, Zhanhui Yu, Wenbo
Published in
Frontiers in Chemistry
Mushrooms containing Amanita peptide toxins are the major cause of mushroom poisoning, and lead to approximately 90% of deaths. Phallotoxins are the fastest toxin causing poisoning among Amanita peptide toxins. Thus, it is imperative to construct a highly sensitive quantification method for the rapid diagnosis of mushroom poisoning. In this study, ...
