El Rawas, Rana Klement, Sabine Kummer, Kai K. Fritz, Michael Dechant, Georg Saria, Alois Zernig, Gerald
Published in
Frontiers in Behavioral Neuroscience
Positive social interaction could play an essential role in switching the preference of the substance dependent individual away from drug related activities. We have previously shown that conditioned place preference (CPP) for cocaine at the dose of 15 mg/kg and CPP for four 15-min episodes of social interaction were equally strong when rats were c...
Parsons, Ryan G. Gafford, Georgette M. Helmstetter, Fred J.
Published in
Frontiers in Behavioral Neuroscience
Recent work has led to a better understanding of the neural mechanisms underlying the extinction of Pavlovian fear conditioning. Long-term synaptic changes in the medial prefrontal cortex (mPFC) are critical for extinction learning, but very little is currently known about how the mPFC and other brain areas interact during extinction. The current s...
Poirier, Roseline Cheval, Hélène Mailhes, Caroline Charnay, Patrick Davis, Sabrina Laroche, Serge
Published in
Frontiers in behavioral neuroscience
It is well established that Egr1/zif268, a member of the Egr family of transcription factors, is critical for the consolidation of several forms of memories. Recently, the Egr3 family member has also been implicated in learning and memory. Because Egr family members encode closely related zinc-finger transcription factors sharing a highly homologou...
Sandoz, Jean-Christophe Deisig, Nina de Brito Sanchez, Maria Gabriela Giurfa, Martin
Published in
Frontiers in behavioral neuroscience
Honeybees employ a very rich repertoire of pheromones to ensure intraspecific communication in a wide range of behavioral contexts. This communication can be complex, since the same compounds can have a variety of physiological and behavioral effects depending on the receiver. Honeybees constitute an ideal model to study the neurobiological basis o...
Bikbaev, Arthur Manahan-Vaughan, Denise
Published in
Frontiers in behavioral neuroscience
A role for oscillatory activity in hippocampal neuronal networks has been proposed in sensory encoding, cognitive functions and synaptic plasticity. In the hippocampus, theta (5-10 Hz) and gamma (30-100 Hz) oscillations may provide a mechanism for temporal encoding of information, and the basis for formation and retrieval of memory traces. Long-ter...
Feyder, Michael Wiedholz, Lisa Sprengel, Rolf Holmes, Andrew
Published in
Frontiers in behavioral neuroscience
There is compelling evidence that l-alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA) glutamate receptors containing the GluR1 subunit contribute to the molecular mechanisms associated with learning. AMPA GluR1 glutamate receptor knockout mice (KO) exhibit abnormal hippocampal and amygdala plasticity, and deficits on various assays for co...
Fiocco, Alexandra J Joober, Ridha Poirier, Judes Lupien, Sonia
Published in
Frontiers in behavioral neuroscience
Past research has concentrated on the stress system and personality in order to explain the variance found in cognitive performance in old age. A growing body of research is starting to focus on genetic polymorphism as an individual difference factor to explain the observed heterogeneity in cognitive function. While the functional mechanism is stil...
Yang, Mu Scattoni, Maria Luisa Zhodzishsky, Vladimir Chen, Thomas Caldwell, Heather Young, W Scott McFarlane, Hewlet G Crawley, Jacqueline N
Published in
Frontiers in behavioral neuroscience
Mice are a nocturnal species, whose social behaviors occur primarily during the dark phase of the circadian cycle. However, laboratory rodents are frequently tested during their light phase, for practical reasons. We investigated the question of whether light phase testing presents a methodological pitfall for investigating mouse social approach be...
Valenchon, Mathilde Lévy, Frédéric Górecka-Bruzda, Aleksandra Calandreau, Ludovic Lansade, Léa
Published in
Animal Cognition
The present study investigated the influence of temperament on long-term recall and extinction of 2 instrumental tasks in 26 horses. In the first task (backward task), horses learned to walk backward, using commands given by an experimenter, in order to obtain a food reward. In the second task (active avoidance task), horses had to cross an obstacl...
Tsujimura, Atsushi Matsuki, Masato Takao, Keizo Yamanishi, Kiyofumi Miyakawa, Tsuyoshi Hashimoto-Gotoh, Tamotsu
Published in
Frontiers in behavioral neuroscience
KF-1 was originally identified as a protein encoded by human gene with increased expression in the cerebral cortex of a patient with Alzheimer's disease. In mouse brain, kf-1 mRNA is detected predominantly in the hippocampus and cerebellum, and kf-1 gene expression is elevated also in the frontal cortex of rats after chronic antidepressant treatmen...