Ikeda, Kenji Kawamura, Yusuke Kobayashi, Masahiro Kominami, Yoko Fujiyama, Shunichiro Sezaki, Hitomi Hosaka, Tetsuya Akuta, Norio Saitoh, Satoshi Suzuki, Fumitaka
...
Published in
Digestive Diseases and Sciences
BackgroundSuppressive activity of recurrence by interferon-free direct-acting antivirals (DAA) is not elucidated after curative treatment of hepatocellular carcinoma (HCC).Patients and MethodsA total of 177 patients received DAA after curative manners of HCC: 89 patients underwent DAA therapy after initial HCC treatment, and the other 88 patients a...
Boland, C. Richard
Published in
Digestive Diseases and Sciences
Matsumi, Akihiro Takenaka, Ryuta Ando, Chihiro Sato, Yuki Takei, Kensuke Yasutomi, Eriko Okanoue, Shotaro Oka, Shohei Kawai, Daisuke Kataoka, Junro
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Published in
Digestive Diseases and Sciences
BackgroundESD allows higher rates of en-bloc and R0 resections, but has occasionally complications such as aspiration pneumonia. Factors associated with aspiration pneumonia are not completely understood.AimsTo analyze the relationship between aspiration pneumonia and preoperative factors including pulmonary function tests.MethodsA total of 978 pat...
Boscarino, Joseph A. Moorman, Anne C. Rupp, Loralee B. Zhou, Yueren Lu, Mei Teshale, Eyasu H. Gordon, Stuart C. Spradling, Philip R. Schmidt, Mark A. Trinacty, Connie Mah
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Published in
Digestive Diseases and Sciences
BackgroundResearch suggests depression and alcohol misuse are highly prevalent among chronic hepatitis C (CHC) patients, which is of clinical concern.AimsTo compare ICD-9 codes for depression and alcohol misuse to validated survey instruments.MethodsAmong CHC patients, we assessed how well electronic ICD-9 codes for depression and alcohol misuse pr...
Du Jeong, In Jung, Seok Won Park, Bo Ryung Lee, Byung Uk Park, Jae Ho Kim, Byung Gyu Bang, Sung-Jo Shin, Jung Woo Park, Neung Hwa
Published in
Digestive Diseases and Sciences
Background/AimsThe clinical course of chronic hepatitis B (CHB) patients with partial virologic response (PVR) during tenofovir disoproxil fumarate (TDF) therapy remains unclear.MethodsWe retrospectively investigated the long-term clinical outcomes of TDF treatment in nucleos(t)ides-naïve CHB patients, particularly in those with PVR.ResultsA total ...
Triadafilopoulos, George Lewis, David
Published in
Digestive Diseases and Sciences
Dong, Shouquan Singh, Tikka Prabhjot Wei, Xin Yao, Huang Wang, Hongling
Published in
Digestive Diseases and Sciences
Background Tight junction (TJ) injuries induced by pepsin–trypsin-resistant gliadin (PT–G) play an important role in the pathogenesis of celiac disease. Previously, 1,25-dihydroxy vitamin D3 (VD3) was reported to be a TJ regulator that attenuates lipopolysaccharide- and alcohol-induced TJ injuries. However, whether VD3 can attenuate PT–G-induced TJ...
Gray, Marcus Holtmann, Gerald
Published in
Digestive Diseases and Sciences
Mendelson, Aaron H. Donowitz, Mark
Published in
Digestive Diseases and Sciences
Zollinger–Ellison syndrome (ZES) results from an ectopic gastrin-secreting tumor leading to peptic ulcer disease, reflux, and chronic diarrhea. While early recognition portends an excellent prognosis with >80% survival at 15 years, symptoms are often nonspecific making the diagnosis difficult to establish. Diagnosis involves a series of tests, incl...
Czaja, Albert J.
Published in
Digestive Diseases and Sciences
Autoimmune hepatitis has a variable occurrence, clinical phenotype, and outcome, and the factors contributing to this variability are uncertain. The goals of this review are to examine the global disparities in the occurrence and outcome of autoimmune hepatitis, suggest bases for these disparities, and encourage investigations that extend beyond si...