Kristensson, Felipe M Andersson-Assarsson, Johanna C Svensson, Per-Arne Carlsson, Björn Peltonen, Markku Carlsson, Lena M S
Published in
Diabetes care
Bariatric surgery is an effective treatment for obesity, but it is unknown if outcomes differ between adults with early- versus adult-onset obesity. We investigated how obesity status at 20 years of age affects outcomes after bariatric surgery later in life. The Swedish Obese Subjects study is a prospective matched study performed at 25 surgical de...
Parry, Siôn A Rosqvist, Fredrik Mozes, Ferenc E Cornfield, Thomas Hutchinson, Matthew Piche, Marie-Eve Hülsmeier, Andreas J Hornemann, Thorsten Dyson, Pamela Hodson, Leanne
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Published in
Diabetes care
Debate continues regarding the influence of dietary fats and sugars on the risk of developing metabolic diseases, including insulin resistance and nonalcoholic fatty liver disease (NAFLD). We investigated the effect of two eucaloric diets, one enriched with saturated fat (SFA) and the other enriched with free sugars (SUGAR), on intrahepatic triacyl...
Haidar, Ahmad Tsoukas, Michael A Bernier-Twardy, Sarah Yale, Jean-Francois Rutkowski, Joanna Bossy, Anne Pytka, Evelyne El Fathi, Anas Strauss, Natalia Legault, Laurent
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Published in
Diabetes care
The rapid insulin-alone artificial pancreas improves glycemia in type 1 diabetes but daytime control remains suboptimal. We propose two novel dual-hormone artificial pancreas systems. We conducted a randomized crossover trial comparing a rapid insulin-alone artificial pancreas with rapid insulin-and-pramlintide and with regular insulin-and-pramlint...
Choi, Sung Eun Sima, Corneliu Pandya, Ankur
Published in
Diabetes care
Previous randomized trials found that treating periodontitis improved glycemic control in patients with type 2 diabetes (T2D), thus lowering the risks of developing T2D-related microvascular diseases and cardiovascular disease (CVD). Some payers in the U.S. have started covering nonsurgical periodontal treatment for those with chronic conditions, s...
Ferrara-Cook, Christine Geyer, Susan Michelle Evans-Molina, Carmella Libman, Ingrid M Becker, Dorothy J Gitelman, Stephen E Redondo, Maria Jose
Published in
Diabetes care
Sustained excess BMI increases the risk of type 1 diabetes (T1D) in autoantibody-positive relatives without diabetes of patients. We tested whether elevated BMI also accelerates the progression of islet autoimmunity before T1D diagnosis. We studied 706 single autoantibody-positive pediatric TrialNet participants (ages 1.6-18.6 years at baseline). C...
Standl, Eberhard Stevens, Susanna R Lokhnygina, Yuliya Bethel, M Angelyn Buse, John B Gustavson, Stephanie M Maggioni, Aldo P Mentz, Robert J Hernandez, Adrian F Holman, Rury R
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Published in
Diabetes care
We sought to confirm a bidirectional association between severe hypoglycemic events (SHEs) and cardiovascular (CV) event risk and to characterize individuals at dual risk. In a post hoc analysis of 14,752 Exenatide Study of Cardiovascular Event Lowering (EXSCEL) participants, we examined time-dependent associations between SHEs and subsequent major...
Frykberg, Robert G Franks, Peter J Edmonds, Michael Brantley, Jonathan N Téot, Luc Wild, Thomas Garoufalis, Matthew G Lee, Aliza M Thompson, Janette A Reach, Gérard
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Published in
Diabetes care
Topical oxygen has been used for the treatment of chronic wounds for more than 50 years. Its effectiveness remains disputed due to the limited number of robust high-quality investigations. The aim of this study was to assess the efficacy of multimodality cyclical pressure Topical Wound Oxygen (TWO2) home care therapy in healing refractory diabetic ...
Succurro, Elena Pedace, Elisabetta Andreozzi, Francesco Papa, Annalisa Vizza, Patrizia Fiorentino, Teresa Vanessa Perticone, Francesco Veltri, Pierangelo Cascini, Giuseppe Lucio Sesti, Giorgio
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Published in
Diabetes care
Impaired insulin-stimulated myocardial glucose uptake has occurred in patients with type 2 diabetes with or without coronary artery disease. Whether cardiac insulin resistance is present remains uncertain in subjects at risk for type 2 diabetes, such as individuals with impaired glucose tolerance (IGT) or those with normal glucose tolerance (NGT) a...
Aminian, Ali Vidal, Josep Salminen, Paulina Still, Christopher D Nor Hanipah, Zubaidah Sharma, Gautam Tu, Chao Wood, G Craig Ibarzabal, Ainitze Jimenez, Amanda
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Published in
Diabetes care
To characterize the status of cardiometabolic risk factors after late relapse of type 2 diabetes mellitus (T2DM) and to identify factors predicting relapse after initial diabetes remission following bariatric surgery to construct prediction models for clinical practice. Outcomes of 736 patients with T2DM who underwent Roux-en-Y gastric bypass (RYGB...
Peterson, Kevin A Carlin, Caroline Solberg, Leif I Jacobsen, Rachel Kriel, Toni Eder, Milton
Published in
Diabetes care
The effective redesign of primary care delivery systems to improve diabetes care requires an understanding of which particular components of delivery consistently lead to better clinical outcomes. We identified associations between common systems of care management (SysCMs) and the frequency of meeting standardized performance targets for Optimal D...
