Rosenstock, Julio Nino, Antonio Soffer, Joseph Erskine, Lois Acusta, Andre Dole, Jo Carr, Molly C. Mallory, Jason Home, Philip
Published in
Diabetes Care
OBJECTIVE The principle of replacing prandial insulin lispro with a once-weekly glucagon-like peptide 1 receptor agonist (GLP-1RA) for type 2 diabetes inadequately controlled on a multiple daily insulin injections regimen was tested with albiglutide. RESEARCH DESIGN AND METHODS In this treat-to-target study, basal plus prandial insulin was optimize...
Deshmukh, Harshal Wilmot, Emma G. Gregory, Robert Barnes, Dennis Narendran, Parth Saunders, Simon Furlong, Niall Kamaruddin, Shafie Banatwalla, Rumaisa Herring, Roselle
...
Published in
Diabetes Care
OBJECTIVE The FreeStyle Libre (FSL) flash glucose-monitoring device was made available on the U.K. National Health Service (NHS) drug tariff in 2017. This study aims to explore the U.K. real-world experience of FSL and the impact on glycemic control, hypoglycemia, diabetes-related distress, and hospital admissions. RESEARCH DESIGN AND METHODS Clini...
Christensen, Alexander S. Hædersdal, Sofie Støy, Julie Storgaard, Heidi Kampmann, Ulla Forman, Julie L. Seghieri, Marta Holst, Jens J. Hansen, Torben Knop, Filip K.
...
Published in
Diabetes Care
OBJECTIVE Sulfonylureas are first-line treatment of hepatocyte nuclear factor 1-α (HNF1A) diabetes (maturity-onset diabetes of the young type 3), but many patients do not achieve optimal glycemic control without episodes of hypoglycemia. We investigated the combination of the sulfonylurea glimepiride and the dipeptidyl peptidase 4 inhibitor linagli...
Bellastella, Giuseppe Maiorino, Maria Ida Esposito, Katherine
Published in
Diabetes Care
Gan, Sushrima Dawed, Adem Y. Donnelly, Louise A. Nair, Anand T.N. Palmer, Colin N.A. Mohan, Viswanathan Pearson, Ewan R.
Published in
Diabetes Care
BACKGROUND The pathophysiology of type 2 diabetes differs markedly by ethnicity. PURPOSE A systematic review and meta-analysis was conducted to assess the impact of ethnicity on the glucose-lowering efficacy of the newer oral agents, sodium–glucose cotransporter 2 inhibitors (SGLT-2i), glucagon-like peptide 1 receptor agonists (GLP-1RA), and dipept...
Lee, Angela S. Johnson, Nathan A. McGill, Margaret J. Overland, Jane Luo, Connie Baker, Callum J. Martinez-Huenchullan, Sergio Wong, Jencia Flack, Jeffrey R. Twigg, Stephen M.
...
Published in
Diabetes Care
OBJECTIVE To study the effect of 12 weeks of high-intensity interval training (HIIT) on glycemic control in adults with type 1 diabetes and overweight or obesity. RESEARCH DESIGN AND METHODS Thirty inactive adults with type 1 diabetes who had BMI ≥25 kg/m2 and HbA1c ≥7.5% were randomized to 12 weeks of either HIIT exercise intervention consisting o...
Hampp, Christian Swain, Richard S. Horgan, Casie Dee, Elizabeth Qiang, Yandong Dutcher, Sarah K. Petrone, Andrew Tilney, Rong Chen Maro, Judith C. Panozzo, Catherine A.
...
Published in
Diabetes Care
Seyed Ahmadi, Shilan Westman, Klara Pivodic, Aldina Ólafsdóttir, Arndís F. Dahlqvist, Sofia Hirsch, Irl B. Hellman, Jarl Ekelund, Magnus Heise, Tim Polonsky, William
...
Published in
Diabetes Care
OBJECTIVE According to recent guidelines, individuals with type 1 diabetes should spend
Samoa, Raynald A. Lee, Hayley S. Kil, Sung H. Roep, Bart O.
Published in
Diabetes Care
OBJECTIVE Immune checkpoint inhibitors (ICIs) perturb T-cell regulatory pathways to enhance antitumor immunity. However, an increase reporting of ICI-associated diabetes is observed in adults. To our knowledge, no cases have been reported in the pediatric population. RESEARCH DESIGN AND METHODS We describe a pediatric case of ICI-associated type 1 ...
Tan, Xiao Benedict, Christian
Published in
Diabetes Care
OBJECTIVE The common MTNR1B single nucleotide polymorphism rs10830963 associates with risk of type 2 diabetes (T2D). Here, we examine the association between this gene variant and the risk of myocardial infarction (MCI) among patients with T2D. MCI is a main cause of death and disability among such individuals. RESEARCH DESIGN AND METHODS Data from...