Pinto, Tiago Coimbra Costa Machado, Leonardo Costa, Maria Lúcia G. Santos, Marilia S.P. Bulgacov, Tatiana M. Rolim, Ana Paula P. Silva, Gabriela A. Rodrigues-Júnior, Antônio L. Sougey, Everton B. Ximenes, Rosana C.C.
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Published in
Dementia and Geriatric Cognitive Disorders
Objective: To evaluate the applicability and the psychometric properties of Montreal Cognitive Assessment Brazilian Version (MoCA-BR) in the elderly, as well as comparing its accuracy as a tracking test for mild cognitive impairment (MCI) and mild Alzheimer’s disease (AD) with the accuracy of Mini-Mental State Examination (MMSE). Method: A transver...
Hsu, Yen-Hsuan Huang, Ching-Feng Huang, Wen-Hui Deng, Jie-Fu Tu, Min-Chien
Published in
Dementia and Geriatric Cognitive Disorders
Background: An increasing number of studies suggest the importance of prospective memory (ProM) due to its functional relevance and sensitivity to neuropathology. However, its relevant neural substrates have not been sufficiently explored. Objectives: The present study aimed to investigate the relationship between structural connectivity and both o...
Amieva, Hélène Meillon, Céline Proust-Lima, Cécile Dartigues, Jean François
Published in
Dementia and Geriatric Cognitive Disorders
Background: Dementia, stroke, depression, and disability are frequent in late life and are major causes of quality of life disruption and family burden. Even though each of these disorders relies on specific pathogenic processes, a common clinical manifestation is psychomotor slowing. Objective: We assessed the relevance of a simple marker of low p...
Rodriguez, Francisca S. Zheng, Ling Chui, Helena C.
Published in
Dementia and Geriatric Cognitive Disorders
Background: The capacity to mitigate dementia symptomology despite the prevailing brain pathology has been attributed to cognitive reserve. Objectives: This study aimed to investigate how psychometric performance differs between individuals with a high school versus college education (surrogate measures for medium and high cognitive reserves) given...
Andriuta, Daniela Diouf, Momar Roussel, Martine Godefroy, Olivier
Published in
Dementia and Geriatric Cognitive Disorders
Background: Although simple reaction time (SRT) slowing is associated with dementia in Alzheimer’s disease (AD), its presence in individuals with mild cognitive impairment (MCI) is subject to debate. Objective: The aim of this study was to perform a systematic review and meta-analysis of the literature data on SRT slowing in MCI. Methods: Publicati...
Gregory, Michael A. Manuel-Apolinar, Leticia Sánchez-Garcia, Sergio Villa Romero, Antonio R. de Jesús Iuit Rivera, Jaime Basurto Acevedo, Lourdes Grijalva-Otero, Israel Cuadros-Moreno, Juan Garcia-de la Torre, Paola Guerrero Cantera, Jose
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Published in
Dementia and Geriatric Cognitive Disorders
Background: Endothelial dysfunction and subsequent inflammation contribute to the development of vascular cognitive impairment (VCI). Soluble intercellular adhesion molecule-1 (sICAM-1) is upregulated in endothelial dysfunction and promotes an inflammatory response; however, the relationship between sICAM-1 and VCI remains equivocal. Objective: To ...
Karadag Caman, Ozge Karahan, Sevilay Ünal, Ferhat Bilir, Nazmi Saka, Esen Barışkın, Elif Ayhan, Yavuz
Published in
Dementia and Geriatric Cognitive Disorders
Background/Aims: This study aimed to adapt the Modified Mini-Mental State Examination (3MS) and determine its normative values in Turkey. Methods: After translation and cultural adaptation processes, a population-based study was conducted between February and June 2016 in Ankara with individuals over the age of 55 years. Subjects with a previous di...
Franzen, Sanne van den Berg, Esther Kalkisim, Yuled van de Wiel, Lotte Harkes, Marleen van Bruchem-Visser, Rozemarijn L. de Jong, Frank Jan Jiskoot, Lize C. Papma, Janne M.
Published in
Dementia and Geriatric Cognitive Disorders
Background: Neuropsychological tests are influenced by culture, language, level of education, and literacy, but there are few cognitive tests of which the applicability in ethnic minority populations has been studied. Objectives: The aim of this study was to assess the reliability and validity of the Visual Association Test (VAT), a test of visual ...
Strand, Bjørn Heine Knapskog, Anne-Brita Persson, Karin Holt Edwin, Trine Bjertness, Espen Engedal, Knut Selbaek, Geir
Published in
Dementia and Geriatric Cognitive Disorders
Introduction: Whether patients with early-onset dementia have poorer or improved survival compared with those with a late onset largely depends on the survival measure. Survival estimates for early-onset mild cognitive impairment (MCI) diagnosis are particularly scarce. We aimed to estimate life expectancy (LE) in patients with early-onset dementia...
Ishunina, Tatjana A. Bogolepova, Irina N. Swaab, Dick F.
Published in
Dementia and Geriatric Cognitive Disorders
Background: The hypothalamic medial mamillary (MMN) and the tuberomamillary (TMN) nuclei are important hubs in memory circuits. Previous studies determining the neuronal Golgi complex size showed decreased metabolic activity of the TMN neurons in both Alzheimer’s disease (AD) and vascular dementia (VD), and no obvious decline in the MMN of these p...
