Treviño, Samuel Cortezano-Esteban, Steffany Hernández-Fragoso, Hugo Díaz, Alfonso Vázquez-Roque, Rubén Enrique Sarmiento-Ortega, Victor Moroni-González, Diana Pelayo, Rosana Brambila, Eduardo
Published in
Cytokine
The COVID-19 disease has forced us to consider the physiologic role of obesity and metabolically healthy and unhealthy status in response to SARS-CoV-2 infection. Hematological, coagulation, biochemical, and immunoinflammatory changes have been informed with a disparity in morbidity and mortality. Therefore, we aimed to investigate the influence of...
Pretre, Vincent Papadopoulos, Dimitrios Regard, Jean Pelletier, Marc Woo, Janghee
Published in
Cytokine
Numerous preclinical and clinical studies have demonstrated the significant contribution of inflammation to the development and progression of various types of cancer. Inflammation in the tumor microenvironment mediates complex interactions between innate immunity, adaptive immunity, microbiomes and stroma, and ultimately alters the overall fitness...
Serin, Istemi Oyaci, Yasemin Pehlivan, Mustafa Pehlivan, Sacide
Published in
Cytokine
The IL-1 receptor antagonist (IL-1Ra or IL-1RN) is a member of the IL-1 superfamily that functions as a competitive antagonist of the cell surface IL-1 receptor, thereby regulating various immune and inflammatory responses related to IL-1. IL-1 induces tumor growth and metastasis, while IL-1RN inhibits the secretion of IL-1α and IL-6 in cancer cell...
Wu, Shuwen Zhang, Yuan Ma, Jingchang Liu, Yongming Li, Wenpeng Wang, Tingting Xu, Xuexue Wang, Yuling Cheng, Kun Zhuang, Ran
...
Published in
Cytokine
Interleukin-6 (IL-6) in mucosal immune cells is involved in post-injury intestinal regeneration, inflammation responses, and gastric homeostasis. However, the interaction between IL-6 and the dynamic balance of gut microbiota (GM) remains unexplored. Intestinal pathology was assessed by hematoxylin and eosin and periodic acid-Schiff staining in wil...
Jafarzadeh, Abdollah Kumar, Sunil Bodhale, Neelam Jafarzadeh, Sara Nemati, Maryam Sharifi, Iraj Sarkar, Arup Saha, Bhaskar
Published in
Cytokine
The expression of programmed cell death protein-1 (PD-1) and its ligands- PD-L1 and PD-L2- on T cells and macrophages', respectively, increases in Leishmania infection. The PD-1/PD-L1 interaction induces T cell anergy, T cell apoptosis and exhaustion, diversion of T cells toward TH2 and T-reg cells but inhibits M1 macrophage activities by suppressi...
Imoto, Sahoko Suzukawa, Maho Takeda, Keita Asari, Isao Watanabe, Shizuka Tohma, Shigeto Nagase, Takahide Ohta, Ken Teruya, Katsuji Nagai, Hideaki
...
Published in
Cytokine
Human immunodeficiency virus-1 (HIV-1) infection causes loss and anergy of CD4+ and CD8+ T cells, leading to opportunistic infections, including tuberculosis (TB). QuantiFERON®-TB (QFT) is used as a diagnostic tool to detect TB, but it exhibits limited accuracy among subjects with low CD4+ T cell numbers, including HIV-1-infected individuals. The p...
Mendes Roatt, Bruno Mirelle de Oliveira Cardoso, Jamille Cristiane Fortes de Brito, Rory Eduardo Soares Reis, Levi José Lucas Moreira, Gabriel Melo de Abreu Vieira, Paula Marques de Souza, Flávia Geraldo de Lima, Wanderson Dian de Oliveira Aguiar-Soares, Rodrigo Cordeiro Giunchetti, Rodolfo
...
Published in
Cytokine
The liver plays an important role in human and canine visceral leishmaniasis, then it is considered as target to understand the mechanisms involved in the parasite control and a parameter to assess therapeutic responses. In this sense, our study focuses on evaluating the major alterations in the liver by histological (morphometric parenchyma inflam...
Wu, Qianqian Li, Shanshan Li, Ran Chen, Xuejiao Guo, Lingzi Zheng, Ying
Published in
Cytokine
This research aims to quantify pro-inflammatory cytokines from the exudates of dental pulp tissues are helpful in the diagnosis of pulpitis, thus, laying down the foundation for further vital pulp therapy on irreversible pulpitis. The authors selected patients admitted to Beijing Stomatological Hospital from October 2016 to March 2018. Exudates wer...
Selvaraju, Vaithinathan Babu, Jeganathan R Geetha, Thangiah
Published in
Cytokine
Obesity increases the risk of developing insulin resistance, diabetes, and cardiovascular disease. The current study is designed to evaluate the association of salivary fetuin-A, insulin, and adiponectin with the obesity measures in children. Seventy-six children aged 6-10 years participated in the study. Anthropometric measurements were recorded, ...
Akbari, Mohammadarian Akhavan-Bahabadi, Mehdi Shafigh, Navid Taheriazam, Afshin Hussen, Bashdar Mahmud Sayad, Arezou Fathi, Mohadeseh Taheri, Mohammad Ghafouri-Fard, Soudeh Fathi, Mohammad
...
Published in
Cytokine
As a member of JAK family of non-receptor tyrosine kinases, TYK2 has a crucial role in regulation of immune responses. This protein has a crucial role in constant expression of IFNAR1 on surface of cells and initiation of type I IFN signaling. In the current study, we measured expression of IFNAR1 and TYK2 levels in venous blood samples of COVID-19...
