Lee, Noah Smith, R Theodore Laine, Andrew F
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
Fundus auto-fluorescence (FAF) imaging is a non-invasive technique for in vivo ophthalmoscopic inspection of age-related macular degeneration (AMD), the most common cause of blindness in developed countries. Geographic atrophy (GA) is an advanced form of AMD and accounts for 12-21% of severe visual loss in this disorder [3]. Automatic quantificatio...
Chao, Jerry Ward, E Sally Ober, Raimund J
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
Owing to its high quantum efficiency, the charge-coupled device (CCD) is an important imaging tool employed in biological applications such as single molecule microscopy. Under extremely low light conditions, however, a CCD is generally unsuitable because its readout noise can easily overwhelm the weak signal. Instead, an electron-multiplying charg...
Ingle, A N Sethares, W A Varghese, T Bucklew, J A
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
This paper presents a method for directly estimating slope values in a noisy piecewise linear function. By imposing a Markov structure on the sequence of slopes, piecewise linear fitting is posed as a maximum a posteriori estimation problem. A dynamic program efficiently solves this by traversing a linearly growing trellis. The alternating maximiza...
Sornborger, Andrew T Lauderdale, James D
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
Neural data analysis has increasingly incorporated causal information to study circuit connectivity. Dimensional reduction forms the basis of most analyses of large multivariate time series. Here, we present a new, multitaper-based decomposition for stochastic, multivariate time series that acts on the covariance of the time series at all lags, C(τ...
Khanmohammadi, Sina Kummer, Terrance T Ching, ShiNung
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
Recent studies suggest that disruptions in resting state functional connectivity - a measure of stationary statistical association between brain regions - can be used as an objective marker of brain injury. However, fewer characterizations have examined the disruption of intrinsic brain dynamics after brain injury. Here, we examine this issue using...
Garudadri, Harinath Boothroyd, Arthur Lee, Ching-Hua Gadiyaram, Swaroop Bell, Justyn Sengupta, Dhiman Hamilton, Sean Vastare, Krishna Chaithanya Gupta, Rajesh Rao, Bhaskar D
...
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
We are developing a realtime, wearable, open-source speech-processing platform (OSP) that can be configured at compile and run times by audiologists and hearing aid (HA) researchers to investigate advanced HA algorithms in lab and field studies. The goals of this contribution are to present the current system and propose areas for enhancements and ...
Mehta, Ketan Kliewer, Jörg Ihlefeld, Antje
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
Studies increasingly show that behavioral relevance alters the population representation of sensory stimuli in the sensory cortices. However, the mechanisms underlying this behavior are incompletely understood. Here, we record neuronal responses in the auditory cortex while a highly trained, awake, normal-hearing gerbil listens passively to target ...
Pisha, Louis Hamilton, Sean Sengupta, Dhiman Lee, Ching-Hua Vastare, Krishna Chaithanya Zubatiy, Tamara Luna, Sergio Yalcin, Cagri Grant, Alex Gupta, Rajesh
...
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
We have previously reported a realtime, open-source speech-processing platform (OSP) for hearing aids (HAs) research. In this contribution, we describe a wearable version of this platform to facilitate audiological studies in the lab and in the field. The system is based on smartphone chipsets to leverage power efficiency in terms of FLOPS/watt and...
Lankow, Benjamin S Goldman, Mark S
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
In simplified models of neocortical circuits, inhibition is either modeled in a feedforward manner or through mutual inhibitory interactions that provide for competition between neuronal populations. By contrast, recent work has suggested a critical role for recurrent inhibition as a negative feedback element that stabilizes otherwise unstable recu...
Ward, Scott Cohen, Edward A.K. Adams, Niall
Published in
Conference record. Asilomar Conference on Signals, Systems & Computers
With advances in experimental technologies, the use of biological imaging has grown rapidly and there is need for procedures to combine data arising from different modalities. We propose a procedure to combine yellow fluorescence protein excitation and differential interference contrast microscopy time lapse videos to better estimate the cellular b...
