Sørhus, V Sys, S U Natåns, A Demolder, M J Angelsen, B A
Published in
Computers and biomedical research, an international journal
Based on new advancements in digital technology, we developed a PC- and DSP-based measurement and control system for isolated papillary muscle experiments. High flexibility was obtained through a three level control. Length or force was controlled real-time with a sample frequency of 5000 Hz. Muscle length and up to three segment lengths were measu...
Martín-Baranera, M Sancho, J J Sanz, F
Published in
Computers and biomedical research, an international journal
In the validation of medical expert systems, agreement among different human specialists on a random sample of cases may be taken as a substitute to a missing gold standard. Distance measures between pairs of experts, extensively described in previous studies, do not take into account the influence of chance-expected agreement. A weighted kappa ind...
Sita, G Ramakrishnan, A G
Published in
Computers and biomedical research, an international journal
A wavelet domain nonlinear filtering method for improving the signal-to-noise ratio (SNR) of the evoked potentials (EP) is proposed. The method modifies the selective filtering technique proposed for edge detection in images by Xu et al. for the case of signals which require a smooth transition at the edge points. It identifies the significant feat...
Clariá, F Vallverdú, M Baranowski, R Chojnowska, L Caminal, P
Published in
Computers and biomedical research, an international journal
The RT interval is a measure of the ventricular repolarization and is partially influenced by the sympathovagal balance. The analysis of the variation of the duration of the RT and RR intervals might bring new information about the arrhythmogenic vulnerability and autonomic imbalance. The RR signal and its spectral density (SD) are characterized by...
Rai, A Lopez-Benitez, N Hargis, J D Poduslo, S E
Published in
Computers and biomedical research, an international journal
Genetic linkage calculations can be time consuming, even on a fast computer. The ability to collect large family pedigrees has increased the magnitude of linkage computations. Sequential genetic algorithms have many successful applications in very different domains, but they have a main drawback in their utilization. Evaluations are very time-consu...
Farenc, C Fabreguette, J R Bressolle, F
Published in
Computers and biomedical research, an international journal
This paper presents a new software, Pk-fit, to fit nonlinear models to kinetic and dynamic data. Directly connected to the spreadsheet, a statistical software component manager is available. In the data manager, Pk-fit includes the noncompartmental analysis module, the compartmental analysis module, the nonlinear kinetic process module, the drug ab...
Park, H J Oh, J S Jeong, D U Park, K S
Published in
Computers and biomedical research, an international journal
We propose an automated method for sleep stage scoring using hybrid rule- and case-based reasoning. The system first performs rule-based sleep stage scoring, according to the Rechtschaffen and Kale's sleep-scoring rule (1968), and then supplements the scoring with case-based reasoning. This method comprises signal processing unit, rule-based scorin...
Tafeit, E Möller, R Sudi, K Reibnegger, G
Published in
Computers and biomedical research, an international journal
Subcutaneous adipose tissue thickness was measured in 590 healthy subjects at 15 specific body sites by means of the new optical device, lipometer, providing a high-dimensional and partly highly intercorrelated set of data, which had been analyzed by factor analysis previously. N-2-N back-propagation neural networks are able to perform low-dimensio...
Kovalerchuk, B Triantaphyllou, E Ruiz, J F Torvik, V I Vityaev, E
Published in
Computers and biomedical research, an international journal
This paper introduces a number of reliability criteria for computer-aided diagnostic systems for breast cancer. These criteria are then used to analyze some published neural network systems. It is also shown that the property of monotonicity for the data is rather natural in this medical domain, and it has the potential to significantly improve the...
Koulouris, A Papakonstantinou, G Tsanakas, P
Published in
Computers and biomedical research, an international journal
Multichannel algorithms have been developed for more accurate analysis of electrocardiograms (ECGs). Their benefit is the ability to use the information contained in all simultaneously acquired channels. In this paper we present a multichannel version of a nonsyntactic algorithm, based on length transformation. The proposed algorithm uses a decentr...
