Amiridis, I G Morlon, B
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Comptes rendus des seances de la Societe de biologie et de ses filiales
The aim of this study was to examine isokinetic moment produced by well-trained and sedentary subjects, during plantar flexion, at 13 angular velocities (from -120 to 300 degrees.s-1), under maximal voluntary and superimposed electrical conditions. In order to verify the level of activation of agonist (Soleus (SOL) and Gastrocnemius Medialis (GM)) ...
Toyoda, F Hayashi, H Ohmiya, Y Tanaka, S Mochida, H Matsuda, K Kikuyama, S
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Sodefrin, a novel decapeptide which attracts female newts, Cynops pyrrhogaster was isolated from the abdominal gland of the male of the same species. Synthetic sodefrin was tested for its activity with sexually active females and males and sexually inert females. It attracted only sexually active females. The effect of sodefrin was blocked by a bil...
Stella, V Postaire, E
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Epidemiological and experimental studies suggest that dietary milk products may exert an inhibitory effect on the development of several types of tumors. Some recent experiments in rodents indicate that the antitumor activity of the dairy product is in the protein fraction and more specifically in the whey protein component of milk. It has been dem...
Torreilles, J Guérin, M C
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Comptes rendus des seances de la Societe de biologie et de ses filiales
The results of the present study revealed that peptides derived from bovine casein hydrolysates can promote peroxidase-dependent oxidation of human low-density lipoproteins (LDL). The reaction was independent of the free metal ions but required casein-derived peptides with tryosyl-residues, implying that the tyrosyl radical is a diffusible catalyst...
Mazière, J C Mazière, C
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Comptes rendus des seances de la Societe de biologie et de ses filiales
The effect of the inflammatory cytokins TNF-alpha, oncostatin M and interleukine 1 (IL1) on low density lipoprotein (LDL) oxidative modification have been studied on UNA endothelial cells or U937 monocytes in culture, by measuring the end products of lipid peroxydation (TBARS) and the relative electrophoretic mobility of the particle. TNF-alpha as ...
Luu, B
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Oxysterols, a class of cholesterol oxidation products exhibit several important biological activities. Some of these natural compounds are potent inhibitors of the enzyme HMG-CoA reductase, a key enzyme in the cholesterol biosynthetic pathway. Many studies have been directed towards to the verification of the hypothesis that some oxysterols are end...
Robert, L
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Comptes rendus des seances de la Societe de biologie et de ses filiales
A distinction is made between atheromatous plaque formation and arteriosclerosis, only this second process is strictly age-dependent. Interactions between lipids and constituents of the vascular wall are however involved in both processes, although by different mechanisms. The progressive increase with age of elastase activity is a second important...
Torreilles, J Guérin, M C
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Studies of chemical mechanisms involved in the reactivity of natural or synthetic chimioluminescent compounds show that chimioluminescent phenomena result always from redox reactions associated with energy transfers and often with electron transfers. Therefore, analytical methods based on chimioluminescence are very well adapted to detect and evalu...
Floch, H H Abalain, J H Di Stefano, S Carré, J L Abalain-Colloc, M L
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Comptes rendus des seances de la Societe de biologie et de ses filiales
A genomic library of Pseudomonas testosteroi total DNA constructed from SauIIIA digests ligated to a lambda gt11 vector was probed with different polyclonal antibodies raised against purified 3 alpha-HSD and (3 beta-17 beta)-HSD. Two different clones reacting with one antibody were selected. The clone reacting with (3-17)beta-HSD antibody contained...
Nicolas, J C Boussioux, A M Joyeux, A Balaguer, P Térouanne, B Roux, S Gagne, D Pons, M
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Comptes rendus des seances de la Societe de biologie et de ses filiales
Bioluminescence and chemiluminescence have emerged in the last decade as a major tool for biochemical and biological studies. Several very sensitive assays have been developed in our laboratory such as enzymatic assays, immunoassays and detection of nucleic acids. The use of a new instrumentation allowing to dimensional photon counting has permit t...
