Khadija Moustaid Boubker Nasser Isabelle Baudrimont Rachid Anane Mostafa El Idrissi Abdelhamid Bouzidi Edmond E. Creppy
Published in
Comptes Rendus Biologies
Résumé Des études préalables ont montré que l'environnement marin contient des polluants provenant des rejets industriels, agricoles et domestiques. Les bivalves marins pourraient les concentrer et servir de vecteurs vers l'homme. L'objectif de cette étude est de doser des métaux lourds, tels que le cadmium (Cd), le chrome (Cr) et le plomb (Pb) dan...
Bourel, Dominique Teillaud, Jean-Luc
Published in
Comptes rendus biologies
Engineering monoclonal antibodies, now widely used in the clinic, has made it possible to develop a new generation of antibodies with optimized functional properties. These antibodies should allow a significant improvement of the treatment of diseases where only few drugs are available, if any. However, the cost of treatments with monoclonal antibo...
Moncany, Maurice L J Dalet, Karine Courtois, Pascal R R
Published in
Comptes rendus biologies
Considering that recombinations produce quasispecies in lentivirus spreading, we identified and localized highly conserved sequences that may play an important role in viral ontology. Comparison of entire genomes, including 237 human, simian and non-primate mammal lentiviruses and 103 negative control viruses, led to identify 28 Conserved Lentivira...
Clavel, Jacqueline
Published in
Psychosom Med
Cancer epidemiology has undergone marked development since the 1950s. One of the most spectacular and specific contributions was the demonstration of the massive effect of smoking on the occurrence of lung, larynx, and bladder cancer. Major chemical, physical, and biological carcinogenic agents have been identified in the working environment and in...
Boëlle, Pierre-Yves
Published in
Comptes rendus biologies
Recurrence of communicable diseases is a looming threat for human populations. Factors explaining the recurrences are partially known, involving demographics, biology, and complex relationships with the environment, but no comprehensive theory exists today. Here, we review some recent results obtained in modelling studies with a view to understandi...
Shao, Hong-Bo Song, Wei-Yi Chu, Li-Ye
Published in
Comptes rendus biologies
Considerable progresses have taken place, both in the methodology available to study changes in intracellular cytosolic calcium and in our understanding of calcium signaling cascades, but how calcium signals function in plant drought resistance is questionable. In plant cells, calcium plays roles as a second messenger coupling a wide range of extra...
Bailly, Christophe El-Maarouf-Bouteau, Hayat Corbineau, Françoise
Published in
Comptes rendus biologies
Reactive Oxygen Species (ROS) are continuously produced during seed development, from embryogenesis to germination, but also during seed storage. ROS play a dual role in seed physiology behaving, on the one hand, as actors of cellular signaling pathways and, on the other hand, as toxic products that accumulate under stress conditions. ROS, provided...
Nesi, Nathalie Delourme, Régine Brégeon, Michel Falentin, Cyril Renard, Michel
Published in
Comptes rendus biologies
Oilseed rape (Brassica napus L.) is a major oil crop that also supplies proteins for the feed industry. In order to reduce total cost production, the objective is to increase oil yield while reducing crop inputs (especially nitrogen and pesticides). Concomitantly, it is necessary to anticipate specific uses (e.g., fatty acid composition) and to ens...
Prioul, Jean-Louis Méchin, Valérie Damerval, Catherine
Published in
Comptes rendus biologies
A combined transcriptomic, proteomic and metabolic analysis provided an overview of the main changes occurring in gene expression during maize kernel development. It allowed identifying genes expressed at each developmental stage and the shift occurring from one stage to the other. A major change occurred at the transition from lag phase where fina...
Zhao, Chang-Xing Guo, Ling-Yu Jaleel, Cheruth Abdul Shao, Hong-Bo Yang, Hong-Bing
Published in
Comptes rendus biologies
With the advent of molecular biotechnologies, new opportunities are available for plant physiologists to study the relationships between wheat traits and their genetic control. The functional determinations of all genes that participate in drought adaptation or tolerance reactions are expected to provide an integrated understanding of the biochemic...
